A Novel Role for Pyruvate Kinase M2 as a Corepressor for P53 during the DNA Damage Response in Human Tumor Cells
出版年份 2016 全文链接
标题
A Novel Role for Pyruvate Kinase M2 as a Corepressor for P53 during the DNA Damage Response in Human Tumor Cells
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 291, Issue 50, Pages 26138-26150
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2016-11-04
DOI
10.1074/jbc.m116.737056
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Histone modifications in DNA damage response
- (2016) Lin-Lin Cao et al. Science China-Life Sciences
- No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis
- (2015) Katharina Bluemlein et al. Oncotarget
- PKM2 as a biomarker for chemosensitivity to front-line platinum-based chemotherapy in patients with metastatic non-small-cell lung cancer
- (2014) C Papadaki et al. BRITISH JOURNAL OF CANCER
- Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis
- (2014) Ying-Hua Wang et al. CELL
- SAICAR Induces Protein Kinase Activity of PKM2 that Is Necessary for Sustained Proliferative Signaling of Cancer Cells
- (2014) Kirstie E. Keller et al. MOLECULAR CELL
- PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells
- (2014) Yuhui Jiang et al. Nature Communications
- PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells
- (2013) William J. Israelsen et al. CELL
- Reciprocal Regulation of Protein Kinase and Pyruvate Kinase Activities of Pyruvate Kinase M2 by Growth Signals
- (2013) Xueliang Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PKM2 Regulates Chromosome Segregation and Mitosis Progression of Tumor Cells
- (2013) Yuhui Jiang et al. MOLECULAR CELL
- The ribosomal protein S26 regulates p53 activity in response to DNA damage
- (2013) D Cui et al. ONCOGENE
- p53 N-terminal phosphorylation: a defining layer of complex regulation
- (2012) L. M. M. Jenkins et al. CARCINOGENESIS
- PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
- (2012) Weiwei Yang et al. CELL
- Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression
- (2012) Michael S. Goldberg et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
- (2012) Xueliang Gao et al. MOLECULAR CELL
- ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
- (2012) Weiwei Yang et al. NATURE CELL BIOLOGY
- p53 mutations in cancer
- (2012) Patricia A. J. Muller et al. NATURE CELL BIOLOGY
- Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
- (2012) Dimitrios Anastasiou et al. Nature Chemical Biology
- HDAC Inhibitor L-Carnitine and Proteasome Inhibitor Bortezomib Synergistically Exert Anti-Tumor Activity In Vitro and In Vivo
- (2012) Hongbiao Huang et al. PLoS One
- TFIIB dephosphorylation links transcription inhibition with the p53-dependent DNA damage response
- (2012) J. Shandilya et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth
- (2012) M. Cortes-Cros et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
- (2011) Weibo Luo et al. CELL
- Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
- (2011) Weiwei Yang et al. NATURE
- Modes of p53 Regulation
- (2009) Jan-Philipp Kruse et al. CELL
- Universal sample preparation method for proteome analysis
- (2009) Jacek R Wiśniewski et al. NATURE METHODS
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Pyruvate kinase M2 is a phosphotyrosine-binding protein
- (2008) Heather R. Christofk et al. NATURE
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started