p53 and mitochondrial dysfunction: novel insight of neurodegenerative diseases

Quercetin attenuates neuronal death against aluminum-induced neurodegeneration in the rat hippocampus

(2016) D.R. Sharma et al.   NEUROSCIENCE

Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer

(2016) H Kamino et al.   Oncogenesis

Mitochondrial dysfunction and Parkinson disease: a Parkin-AMPK alliance in neuroprotection

(2015) Liting Hang et al.   Annals of the New York Academy of Sciences

p53 signalling mediates acupuncture-induced neuroprotection in Parkinson's disease

(2015) Ji-Yeun Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell death decision by p53 via control of the mitochondrial membrane

(2015) Nurmaa Dashzeveg et al.   CANCER LETTERS

Natural Compounds Modulating Mitochondrial Functions

(2015) Lara Gibellini et al.   Evidence-based Complementary and Alternative Medicine

Aβ induces PUMA activation: a new mechanism for Aβ-mediated neuronal apoptosis

(2015) Jie Feng et al.   NEUROBIOLOGY OF AGING

Mieap suppresses murine intestinal tumor via its mitochondrial quality control

(2015) Masayuki Tsuneki et al.   Scientific Reports

Tumor Suppressor Protein p53 Promotes 2-Methoxyestradiol-Induced Activation of Bak and Bax, Leading to Mitochondria-Dependent Apoptosis in Human Colon Cancer HCT116 Cells

(2015) Ji Young Lee et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Modulation of mitochondrial function by stem cell-derived cellular components

(2014) Tian Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditionsin vitroandin vivo

(2014) Xing Guo et al.   BIOCHEMICAL JOURNAL

p53 and mitochondrial function in neurons

(2014) David B. Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives

(2014) Anthony H V Schapira et al.   LANCET

Pivotal roles of p53 transcription-dependent and -independent pathways in manganese-induced mitochondrial dysfunction and neuronal apoptosis

(2014) Chunhua Wan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A compound CP-31398 suppresses excitotoxicity-induced neurodegeneration

(2013) Takeshi Fujiwara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial p53 mediates a transcription-independent regulation of cell respiration and interacts with the mitochondrial F₁F₀-ATP synthase

(2013) Marie Bergeaud et al.   CELL CYCLE

Expression of Expanded CAG Transcripts Triggers Nucleolar Stress in Huntington's Disease

(2013) Ho Tsoi et al.   CEREBELLUM

The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering

(2013) D. Ottolini et al.   HUMAN MOLECULAR GENETICS

Inhibition of mitochondrial fragmentation diminishes Huntington’s disease–associated neurodegeneration

(2013) Xing Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

Acute exercise induces tumour suppressor protein p53 translocation to the mitochondria and promotes a p53-Tfam-mitochondrial DNA complex in skeletal muscle

(2013) Ayesha Saleem et al.   JOURNAL OF PHYSIOLOGY-LONDON

SCO2 Induces p53-Mediated Apoptosis by Thr845 Phosphorylation of ASK-1 and Dissociation of the ASK-1-Trx Complex

(2013) E. Madan et al.   MOLECULAR AND CELLULAR BIOLOGY

Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models

(2013) L. Hedskog et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of p53 transactivation functionally interacts with microtubule stabilization to suppress excitotoxicity-induced axon degeneration

(2012) Takeshi Fujiwara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Conformational Altered p53 as an Early Marker of Oxidative Stress in Alzheimer's Disease

(2012) Laura Buizza et al.   PLoS One

Lack of p53 Affects the Expression of Several Brain Mitochondrial Proteins: Insights from Proteomics into Important Pathways Regulated by p53

(2012) Ada Fiorini et al.   PLoS One

High-mobility group A1 protein inhibits p53-mediated intrinsic apoptosis by interacting with Bcl-2 at mitochondria

(2012) F Esposito et al.   Cell Death & Disease

Identification of 14-3-3γ as a Mieap-interacting protein and its role in mitochondrial quality control

(2012) Takafumi Miyamoto et al.   Scientific Reports

Mieap, a p53-Inducible Protein, Controls Mitochondrial Quality by Repairing or Eliminating Unhealthy Mitochondria

(2011) Noriaki Kitamura et al.   PLoS One

Current strategies to target p53 in cancer

(2010) Fang Chen et al.   BIOCHEMICAL PHARMACOLOGY

Mitochondrial Uncoupling Inhibits p53 Mitochondrial Translocation in TPA-Challenged Skin Epidermal JB6 Cells

(2010) Fei Wang et al.   PLoS One

Cisplatin-induced nitrosylation of p53 prevents its mitochondrial translocation

(2009) Emma Hernlund et al.   FREE RADICAL BIOLOGY AND MEDICINE

Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2

(2009) Hua Yang et al.   HUMAN MOLECULAR GENETICS

The mitochondrial p53 pathway

(2008) Angelina V. Vaseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS