Ribosomal RNA 2′- O -methylations regulate translation by impacting ribosome dynamics

Functional and transcriptional profiling of non-coding RNAs in yeast reveal context-dependent phenotypes and in trans effects on the protein regulatory network

(2021) Laura Natalia Balarezo-Cisneros et al.   PLoS Genetics

A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translation

(2021) Yang Yi et al.   NATURE CELL BIOLOGY

RNA helicase-mediated regulation of snoRNP dynamics on pre-ribosomes and rRNA 2′-O-methylation

(2021) Gerald Ryan R Aquino et al.   NUCLEIC ACIDS RESEARCH

Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome

(2021) Pramod R. Bhatt et al.   SCIENCE

Assembly factors chaperone ribosomal RNA folding by isolating helical junctions that are prone to misfolding

(2021) Haina Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive and variable 2’-O-methylation (Nm) in human ribosomal RNA

(2021) Yuri Motorin et al.   RNA Biology

eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide

(2020) Fujun Zhou et al.   RNA

Holistic Optimization of Bioinformatic Analysis Pipeline for Detection and Quantification of 2′-O-Methylations in RNA by RiboMethSeq

(2020) Florian Pichot et al.   Frontiers in Genetics

The energy landscape of −1 ribosomal frameshifting

(2020) Junhong Choi et al.   Science Advances

snoRNPs: Functions in Ribosome Biogenesis

(2020) Sandeep Ojha et al.   Biomolecules

2′-O-Methylation can increase the abundance and lifetime of alternative RNA conformational states

(2020) Hala Abou Assi et al.   NUCLEIC ACIDS RESEARCH

RNA 2’-O-Methylation (Nm) Modification in Human Diseases

(2019) Dilyana G. Dimitrova et al.   Genes

Bcd1p controls RNA loading of the core protein Nop58 during C/D box snoRNP biogenesis

(2019) Arnaud Paul et al.   RNA

Does Functional Specialization of Ribosomes Really Exist?

(2019) Max B Ferretti et al.   RNA

Non-canonical translation initiation in yeast generates a cryptic pool of mitochondrial proteins

(2019) Geoffray Monteuuis et al.   NUCLEIC ACIDS RESEARCH

Germline NPM1 mutations lead to altered rRNA 2′-O-methylation and cause dyskeratosis congenita

(2019) Daphna Nachmani et al.   NATURE GENETICS

Developmental changes of rRNA ribose methylations in the mouse

(2019) Jade Hebras et al.   RNA Biology

A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS

(2019) Mary McMahon et al.   eLife

A conserved Bcd1 interaction essential for box C/D snoRNP biogenesis

(2019) Sohail Khoshnevis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae

(2019) Shardul D. Kulkarni et al.   BMC BIOLOGY

Adjusting the Structure of 2′-Modified Nucleosides and Oligonucleotides via C4′-α-F or C4′-α-OMe Substitution: Synthesis and Conformational Analysis

(2018) Elise Malek-Adamian et al.   JOURNAL OF ORGANIC CHEMISTRY

Large-scale profiling of noncoding RNA function in yeast

(2018) Steven Parker et al.   PLoS Genetics

Landscape of the complete RNA chemical modifications in the human 80S ribosome

(2018) Masato Taoka et al.   NUCLEIC ACIDS RESEARCH

The Multi-structural Forms of Box C/D Ribonucleoprotein Particles

(2018) Ge Yu et al.   RNA

RNA ribose methylation (2′-O-methylation): Occurrence, biosynthesis and biological functions

(2018) Lilia Ayadi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Visualization of chemical modifications in the human 80S ribosome structure

(2017) S. Kundhavai Natchiar et al.   NATURE

AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia

(2017) Fengbiao Zhou et al.   NATURE CELL BIOLOGY

Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons

(2017) Jinsheng Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for rRNA 2′-O-methylation plasticity: Control of intrinsic translational capabilities of human ribosomes

(2017) Jenny Erales et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosomopathies: There’s strength in numbers

(2017) Eric W. Mills et al.   SCIENCE

Structural Insights into the Mechanism of Scanning and Start Codon Recognition in Eukaryotic Translation Initiation

(2017) Alan G. Hinnebusch   TRENDS IN BIOCHEMICAL SCIENCES

How Ribosomes Translate Cancer

(2017) Sergey O. Sulima et al.   Cancer Discovery

Identification of sites of 2′-O-methylation vulnerability in human ribosomal RNAs by systematic mapping

(2017) Sunny Sharma et al.   Scientific Reports

Mapping of Complete Set of Ribose and Base Modifications of Yeast rRNA by RP-HPLC and Mung Bean Nuclease Assay

(2017) Jun Yang et al.   PLoS One

Post-transcriptional Modifications Modulate rRNA Structure and Ligand Interactions

(2016) Jun Jiang et al.   ACCOUNTS OF CHEMICAL RESEARCH

The complete chemical structure ofSaccharomyces cerevisiaerRNA: partial pseudouridylation of U2345 in 25S rRNA by snoRNA snR9

(2016) Masato Taoka et al.   NUCLEIC ACIDS RESEARCH

Illumina-based RiboMethSeq approach for mapping of 2′-O-Me residues in RNA

(2016) Virginie Marchand et al.   NUCLEIC ACIDS RESEARCH

Profiling of 2′-O-Me in human rRNA reveals a subset of fractionally modified positions and provides evidence for ribosome heterogeneity

(2016) Nicolai Krogh et al.   NUCLEIC ACIDS RESEARCH

Translocation as continuous movement through the ribosome

(2016) Riccardo Belardinelli et al.   RNA Biology

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

(2016) Katherine E. Sloan et al.   RNA Biology

Assembly and trafficking of box C/D and H/ACA snoRNPs

(2016) Séverine Massenet et al.   RNA Biology

Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex

(2015) Jose L. Llácer et al.   MOLECULAR CELL

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

(2015) Yury S Polikanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

(2015) Yury S Polikanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An Updated Collection of Sequence Barcoded Temperature-Sensitive Alleles of Yeast Essential Genes

(2015) Megan Kofoed et al.   G3-Genes Genomes Genetics

The Scanning Mechanism of Eukaryotic Translation Initiation

(2014) Alan G. Hinnebusch   Annual Review of Biochemistry

Structured mRNA induces the ribosome into a hyper-rotated state

(2014) Peiwu Qin et al.   EMBO REPORTS

Dynamic pathways of −1 translational frameshifting

(2014) Jin Chen et al.   NATURE

Structural basis for the inhibition of the eukaryotic ribosome

(2014) Nicolas Garreau de Loubresse et al.   NATURE

p53 Acts as a Safeguard of Translational Control by Regulating Fibrillarin and rRNA Methylation in Cancer

(2013) Virginie Marcel et al.   CANCER CELL

Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

(2013) Peter Tessarz et al.   NATURE

The structure of the box C/D enzyme reveals regulation of RNA methylation

(2013) Audrone Lapinaite et al.   NATURE

Eukaryotic rpL10 drives ribosomal rotation

(2013) Sergey O. Sulima et al.   NUCLEIC ACIDS RESEARCH

rRNA Pseudouridylation Defects Affect Ribosomal Ligand Binding and Translational Fidelity from Yeast to Human Cells

(2011) Karen Jack et al.   MOLECULAR CELL

Structural basis for site-specific ribose methylation by box C/D RNA protein complexes

(2011) Jinzhong Lin et al.   NATURE

The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA

(2011) Nicholas J. Watkins et al.   Wiley Interdisciplinary Reviews-RNA

RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs

(2009) D. M. Landry et al.   GENES & DEVELOPMENT

eIF1 Controls Multiple Steps in Start Codon Recognition during Eukaryotic Translation Initiation

(2009) Jagpreet S. Nanda et al.   JOURNAL OF MOLECULAR BIOLOGY

Nucleotide modifications in three functionally important regions of the Saccharomyces cerevisiae ribosome affect translation accuracy

(2009) Agnès Baudin-Baillieu et al.   NUCLEIC ACIDS RESEARCH

Loss of rRNA modifications in the decoding center of the ribosome impairs translation and strongly delays pre-rRNA processing

(2009) X.-h. Liang et al.   RNA

Synthesis and solution conformation studies of the modified nucleoside N4,2′-O-dimethylcytidine (m4Cm) and its analogues

(2008) Santosh K. Mahto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Functional importance of individual rRNA 2'-O-ribose methylations revealed by high-resolution phenotyping

(2008) J. Esguerra et al.   RNA