标题
Conformational strains of pathogenic amyloid proteins in neurodegenerative diseases
作者
关键词
-
出版物
NATURE REVIEWS NEUROSCIENCE
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-05-31
DOI
10.1038/s41583-022-00603-7
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cryo-EM structures of amyloid-β 42 filaments from human brains
- (2022) Yang Yang et al. SCIENCE
- Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy
- (2022) Sofia Lövestam et al. eLife
- Hierarchical chemical determination of amyloid polymorphs in neurodegenerative disease
- (2021) Dan Li et al. Nature Chemical Biology
- Reverse engineering Lewy bodies: how far have we come and how far can we go?
- (2021) Mohamed Bilal Fares et al. NATURE REVIEWS NEUROSCIENCE
- Molecular structure of a prevalent amyloid-β fibril polymorph from Alzheimer's disease brain tissue
- (2021) Ujjayini Ghosh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis
- (2021) Lynn Radamaker et al. Nature Communications
- Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy
- (2021) Sofia Lövestam et al. FEBS Open Bio
- Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607
- (2021) Yang Shi et al. ACTA NEUROPATHOLOGICA
- Four distinct trajectories of tau deposition identified in Alzheimer’s disease
- (2021) Jacob W. Vogel et al. NATURE MEDICINE
- Wild-type α-synuclein inherits the structure and exacerbated neuropathology of E46K mutant fibril strain by cross-seeding
- (2021) Houfang Long et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In situ architecture of neuronal α-Synuclein inclusions
- (2021) Victoria A. Trinkaus et al. Nature Communications
- The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson’s disease brain as revealed by multicolor STED microscopy
- (2021) Tim E. Moors et al. ACTA NEUROPATHOLOGICA
- The expanding amyloid family: Structure, stability, function, and pathogenesis
- (2021) Michael R. Sawaya et al. CELL
- Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease
- (2021) Shengnan Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure-based classification of tauopathies
- (2021) Yang Shi et al. NATURE
- Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
- (2020) Tamta Arakhamia et al. CELL
- Novel tau filament fold in corticobasal degeneration
- (2020) Wenjuan Zhang et al. NATURE
- Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy
- (2020) Mohammad Shahnawaz et al. NATURE
- The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration
- (2020) Anne-Laure Mahul-Mellier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure
- (2020) David R. Boyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distribution patterns of tau pathology in progressive supranuclear palsy
- (2020) Gabor G. Kovacs et al. ACTA NEUROPATHOLOGICA
- Cryo-EM structure of full-length α-synuclein amyloid fibril with Parkinson’s disease familial A53T mutation
- (2020) Yunpeng Sun et al. CELL RESEARCH
- Structures of α-synuclein filaments from multiple system atrophy
- (2020) Manuel Schweighauser et al. NATURE
- Protein transmission in neurodegenerative disease
- (2020) Chao Peng et al. Nature Reviews Neurology
- Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core
- (2020) Calina Glynn et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Parkinson’s disease associated mutation E46K of α-synuclein triggers the formation of a distinct fibril structure
- (2020) Kun Zhao et al. Nature Communications
- Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease
- (2020) Simon Dujardin et al. NATURE MEDICINE
- Cryo-EM structure of an amyloid fibril formed by full-length human prion protein
- (2020) Li-Qiang Wang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Parkinson’s disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM
- (2020) Kun Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- α-synuclein strains that cause distinct pathologies differentially inhibit proteasome
- (2020) Genjiro Suzuki et al. eLife
- Investigating the Structure of Neurotoxic Protein Aggregates Inside Cells
- (2020) Felix J.B. Bäuerlein et al. TRENDS IN CELL BIOLOGY
- Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease
- (2020) Hendrik Wesseling et al. CELL
- Amyloid nomenclature 2018: recommendations by the International Society of Amyloidosis (ISA) nomenclature committee
- (2019) Merrill D. Benson et al. AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
- Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
- (2019) Benjamin Falcon et al. NATURE
- Aggregated Tau activates NLRP3–ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo
- (2019) Ilie-Cosmin Stancu et al. ACTA NEUROPATHOLOGICA
- C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson’s disease
- (2019) Ryan P. McGlinchey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aβ and tau prion-like activities decline with longevity in the Alzheimer’s disease human brain
- (2019) Atsushi Aoyagi et al. Science Translational Medicine
- The Amyloid Phenomenon and Its Significance in Biology and Medicine
- (2019) Christopher M. Dobson et al. Cold Spring Harbor Perspectives in Biology
- Functional Amyloids
- (2019) Daniel Otzen et al. Cold Spring Harbor Perspectives in Biology
- Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases
- (2019) Wenjuan Zhang et al. eLife
- Cellular and regional vulnerability in frontotemporal tauopathies
- (2019) Shelley L. Forrest et al. ACTA NEUROPATHOLOGICA
- Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease
- (2019) Sangjune Kim et al. NEURON
- Pure Autonomic Failure
- (2019) Elizabeth A. Coon et al. MAYO CLINIC PROCEEDINGS
- Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs
- (2019) David R. Boyer et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue
- (2019) Marius Kollmer et al. Nature Communications
- Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts
- (2019) Timo Strohäker et al. Nature Communications
- Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy
- (2019) Ricardo Guerrero-Ferreira et al. eLife
- Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies
- (2018) Chao Peng et al. NATURE
- Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation
- (2018) Feng Luo et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks
- (2018) Michael P. Hughes et al. SCIENCE
- Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation
- (2018) Feng Luo et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cryo-EM structure of alpha-synuclein fibrils
- (2018) Ricardo Guerrero-Ferreira et al. eLife
- Intercellular Spread of Protein Aggregates in Neurodegenerative Disease
- (2018) Albert A. Davis et al. Annual Review of Cell and Developmental Biology
- Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy
- (2018) Yaowang Li et al. CELL RESEARCH
- Structures of filaments from Pick’s disease reveal a novel tau protein fold
- (2018) Benjamin Falcon et al. NATURE
- Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel
- (2018) Binsen Li et al. Nature Communications
- Molecular Pathogenesis of the Tauopathies
- (2018) Jürgen Götz et al. Annual Review of Pathology-Mechanisms of Disease
- Physiological C-terminal truncation of α-synuclein potentiates the prion-like formation of pathological inclusions
- (2018) Zachary A. Sorrentino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytosolic proteostasis through importing of misfolded proteins into mitochondria
- (2017) Linhao Ruan et al. NATURE
- Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes
- (2017) Wei Qiang et al. NATURE
- Cryo-EM structures of tau filaments from Alzheimer’s disease
- (2017) Anthony W. P. Fitzpatrick et al. NATURE
- The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril
- (2017) Einav Tayeb-Fligelman et al. SCIENCE
- Fibril structure of amyloid-β(1–42) by cryo–electron microscopy
- (2017) Lothar Gremer et al. SCIENCE
- Activation of tyrosine kinase c-Abl contributes to α-synuclein–induced neurodegeneration
- (2016) Saurav Brahmachari et al. JOURNAL OF CLINICAL INVESTIGATION
- Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein
- (2016) Marcus D Tuttle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo
- (2016) Sarah K. Kaufman et al. NEURON
- Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril
- (2016) Marielle Aulikki Wälti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathological -synuclein transmission initiated by binding lymphocyte-activation gene 3
- (2016) X. Mao et al. SCIENCE
- Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein
- (2016) Marcus D Tuttle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Molecular and Biological Compatibility with Host Alpha-Synuclein Influences Fibril Pathogenicity
- (2016) Kelvin C. Luk et al. Cell Reports
- Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy
- (2015) Gabor G. Kovacs et al. ACTA NEUROPATHOLOGICA
- Deep clinical and neuropathological phenotyping of Pick disease
- (2015) David J. Irwin et al. ANNALS OF NEUROLOGY
- Chronic Traumatic Encephalopathy: Historical Origins and Current Perspective
- (2015) Philip H. Montenigro et al. Annual Review of Clinical Psychology
- Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice
- (2015) Meaghan Morris et al. NATURE NEUROSCIENCE
- Accumulation of phosphorylated α-synuclein in subpial and periventricular astrocytes in multiple system atrophy of long duration
- (2015) Keiko Nakamura et al. NEUROPATHOLOGY
- Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
- (2015) Stanley B. Prusiner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cysteine cathepsins are essential in lysosomal degradation of α-synuclein
- (2015) Ryan P. McGlinchey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled A , tau, and -synuclein
- (2015) M. Goedert SCIENCE
- Primary age-related tauopathy (PART): a common pathology associated with human aging
- (2014) John F. Crary et al. ACTA NEUROPATHOLOGICA
- Atomic-Resolution Three-Dimensional Structure of Amyloid β Fibrils Bearing the Osaka Mutation
- (2014) Anne K. Schütz et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
- (2014) David W. Sanders et al. NEURON
- Biology and Genetics of Prions Causing Neurodegeneration
- (2013) Stanley B. Prusiner Annual Review of Genetics
- Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue
- (2013) Jun-Xia Lu et al. CELL
- Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
- (2013) Jing L. Guo et al. CELL
- Cryo-electron tomography: The challenge of doing structural biology in situ
- (2013) Vladan Lučić et al. JOURNAL OF CELL BIOLOGY
- Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
- (2013) Mathias Jucker et al. NATURE
- Designed amyloid fibers as materials for selective carbon dioxide capture
- (2013) D. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Amyloid State of Proteins in Human Diseases
- (2012) David Eisenberg et al. CELL
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Direct three-dimensional visualization of membrane disruption by amyloid fibrils
- (2012) L. Milanesi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- The Protein-Folding Problem, 50 Years On
- (2012) K. A. Dill et al. SCIENCE
- Neuropathology underlying clinical variability in patients with synucleinopathies
- (2011) Glenda M. Halliday et al. ACTA NEUROPATHOLOGICA
- Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions
- (2011) Heidi Olzscha et al. CELL
- Molecular basis for amyloid- polymorphism
- (2011) J.-P. Colletier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
- (2010) Ashley R. Winslow et al. JOURNAL OF CELL BIOLOGY
- -SYNUCLEIN ACCUMULATION IN SKIN NERVE FIBERS REVEALED BY SKIN BIOPSY IN PURE AUTONOMIC FAILURE
- (2010) T. Shishido et al. NEUROLOGY
- Protein Folding in the Cytoplasm and the Heat Shock Response
- (2010) R. M. Vabulas et al. Cold Spring Harbor Perspectives in Biology
- Lewy body/α-synucleinopathy in schizophrenia and depression: a preliminary neuropathological study
- (2009) Kurt A. Jellinger ACTA NEUROPATHOLOGICA
- The Common Architecture of Cross-β Amyloid
- (2009) Thomas R. Jahn et al. JOURNAL OF MOLECULAR BIOLOGY
- Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
- (2008) Ganesh M Shankar et al. NATURE MEDICINE
- From the first protein structures to our current knowledge of protein folding: delights and scepticisms
- (2008) Alan R. Fersht NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane
- (2008) M. F. M. Engel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils
- (2008) A. K. Paravastu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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