Cryo-EM structure of an amyloid fibril formed by full-length human prion protein

Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro

(2019) Cassandra Terry et al.   Scientific Reports

Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules

(2019) Benjamin Falcon et al.   NATURE

Full atomistic model of prion structure and conversion

(2019) Giovanni Spagnolli et al.   PLoS Pathogens

Prions, prionoids and protein misfolding disorders

(2018) Claudia Scheckel et al.   NATURE REVIEWS GENETICS

Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp

(2018) Marcus Gallagher-Jones et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp

(2018) Marcus Gallagher-Jones et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Automated map sharpening by maximization of detail and connectivity

(2018) Thomas C. Terwilliger et al.   Acta Crystallographica Section D-Structural Biology

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Genetic PrP Prion Diseases

(2017) Mee-Ohk Kim et al.   Cold Spring Harbor Perspectives in Biology

Ex vivomammalian prions are formed of paired double helical prion protein fibrils

(2016) Cassandra Terry et al.   Open Biology

The Structural Architecture of an Infectious Mammalian Prion Using Electron Cryomicroscopy

(2016) Ester Vázquez-Fernández et al.   PLoS Pathogens

Zinc significantly changes the aggregation pathway and the conformation of aggregates of human prion protein

(2015) Kai Pan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

High-resolution structure of infectious prion protein: the final frontier

(2012) Rodrigo Diaz-Espinoza et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Unifying Role for Prions in Neurodegenerative Diseases

(2012) S. B. Prusiner   SCIENCE

Fibril Formation of the Rabbit/Human/Bovine Prion Proteins

(2011) Zheng Zhou et al.   BIOPHYSICAL JOURNAL

Common Structural Traits across Pathogenic Mutants of the Human Prion Protein and Their Implications for Familial Prion Diseases

(2011) Giulia Rossetti et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange

(2011) Vytautas Smirnovas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Prion hypothesis: the end of the controversy?

(2010) Claudio Soto   TRENDS IN BIOCHEMICAL SCIENCES

Protease-Sensitive Synthetic Prions

(2010) David W. Colby et al.   PLoS Pathogens

Design and construction of diverse mammalian prion strains

(2009) D. W. Colby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural and synthetic prion structure from X-ray fiber diffraction

(2009) H. Wille et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA