标题
Cryo-EM structures of amyloid-β 42 filaments from human brains
作者
关键词
-
出版物
SCIENCE
Volume 375, Issue 6577, Pages 167-172
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2022-01-15
DOI
10.1126/science.abm7285
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular structure of a prevalent amyloid-β fibril polymorph from Alzheimer's disease brain tissue
- (2021) Ujjayini Ghosh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy
- (2021) Sofia Lövestam et al. FEBS Open Bio
- Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease
- (2021) Charles D. Chen et al. ACTA NEUROPATHOLOGICA
- The expanding amyloid family: Structure, stability, function, and pathogenesis
- (2021) Michael R. Sawaya et al. CELL
- The Uppsala APP deletion causes early onset autosomal dominant Alzheimer’s disease by altering APP processing and increasing amyloid β fibril formation
- (2021) María Pagnon de la Vega et al. Science Translational Medicine
- Structure-based classification of tauopathies
- (2021) Yang Shi et al. NATURE
- Amyloid structure determination in RELION-3.1
- (2020) Sjors H. W. Scheres Acta Crystallographica Section D-Structural Biology
- Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in RELION-3.1
- (2020) Jasenko Zivanov et al. IUCrJ
- Structures of α-synuclein filaments from multiple system atrophy
- (2020) Manuel Schweighauser et al. NATURE
- The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s disease
- (2020) Heather H. C. Lau et al. ACTA NEUROPATHOLOGICA
- UCSF ChimeraX : Structure visualization for researchers, educators, and developers
- (2020) Eric F. Pettersen et al. PROTEIN SCIENCE
- Multiple system aging‐related tau astrogliopathy with complex proteinopathy in an oligosymptomatic octogenarian
- (2020) Sigrid Klotz et al. NEUROPATHOLOGY
- Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases
- (2019) Wenjuan Zhang et al. eLife
- Structure of amyloid-β (20-34) with Alzheimer’s-associated isomerization at Asp23 reveals a distinct protofilament interface
- (2019) Rebeccah A. Warmack et al. Nature Communications
- Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
- (2019) Justin M. Long et al. CELL
- Current Developments in Coot for Macromolecular Model Building of Electron Cryo‐microscopy and Crystallographic Data
- (2019) Ana Casañal et al. PROTEIN SCIENCE
- Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue
- (2019) Marius Kollmer et al. Nature Communications
- Evidence of amyloid-β cerebral amyloid angiopathy transmission through neurosurgery
- (2018) Zane Jaunmuktane et al. ACTA NEUROPATHOLOGICA
- Real-space refinement in PHENIX for cryo-EM and crystallography
- (2018) Pavel V. Afonine et al. Acta Crystallographica Section D-Structural Biology
- Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods
- (2018) Airi Tarutani et al. Acta Neuropathologica Communications
- Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold
- (2018) Benjamin Falcon et al. ACTA NEUROPATHOLOGICA
- New tools for automated high-resolution cryo-EM structure determination in RELION-3
- (2018) Jasenko Zivanov et al. eLife
- A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis
- (2018) Jasenko Zivanov et al. IUCrJ
- Helical reconstruction in RELION
- (2017) Shaoda He et al. JOURNAL OF STRUCTURAL BIOLOGY
- Cryo-EM structures of tau filaments from Alzheimer’s disease
- (2017) Anthony W. P. Fitzpatrick et al. NATURE
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease
- (2017) Jay Rasmussen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MolProbity: More and better reference data for improved all-atom structure validation
- (2017) Christopher J. Williams et al. PROTEIN SCIENCE
- Fibril structure of amyloid-β(1–42) by cryo–electron microscopy
- (2017) Lothar Gremer et al. SCIENCE
- Distinct deposition of amyloid-β species in brains with Alzheimer’s disease pathology visualized with MALDI imaging mass spectrometry
- (2017) Nobuto Kakuda et al. Acta Neuropathologica Communications
- Gctf: Real-time CTF determination and correction
- (2016) Kai Zhang JOURNAL OF STRUCTURAL BIOLOGY
- Atomic Resolution Structure of Monomorphic Aβ42 Amyloid Fibrils
- (2016) Michael T. Colvin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril
- (2016) Marielle Aulikki Wälti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amyloid-β pathology and cerebral amyloid angiopathy are frequent in iatrogenic Creutzfeldt-Jakob disease after dural grafting
- (2016) K Frontzek et al. SWISS MEDICAL WEEKLY
- Whole-Exome Sequencing in Familial Parkinson Disease
- (2016) Janice L. Farlow et al. JAMA Neurology
- Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy
- (2015) Zane Jaunmuktane et al. NATURE
- Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease
- (2015) Yiling Xiao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease
- (2015) Yiling Xiao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions
- (2015) Alan Brown et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Neuropathology and biochemistry of Aβ and its aggregates in Alzheimer’s disease
- (2014) Dietmar Rudolf Thal et al. ACTA NEUROPATHOLOGICA
- Atomic-Resolution Three-Dimensional Structure of Amyloid β Fibrils Bearing the Osaka Mutation
- (2014) Anne K. Schütz et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects
- (2014) Robert Vassar et al. JOURNAL OF NEUROCHEMISTRY
- Single App knock-in mouse models of Alzheimer's disease
- (2014) Takashi Saito et al. NATURE NEUROSCIENCE
- Is pathological aging a successful resistance against amyloid-beta or preclinical Alzheimer’s disease?
- (2014) Melissa E Murray et al. Alzheimers Research & Therapy
- Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue
- (2013) Jun-Xia Lu et al. CELL
- High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
- (2013) Shaoxia Chen et al. ULTRAMICROSCOPY
- Trafficking and Proteolytic Processing of APP
- (2013) C. Haass et al. Cold Spring Harbor Perspectives in Medicine
- Clinical, Neuropathologic, and Biochemical Profile of the Amyloid Precursor Protein I716F Mutation
- (2009) Cristina Guardia-Laguarta et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations
- (2008) Chera L Maarouf et al. Molecular Neurodegeneration
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started