Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation
出版年份 2022 全文链接
标题
Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation
作者
关键词
-
出版物
NATURE GENETICS
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-05-27
DOI
10.1038/s41588-022-01066-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation
- (2021) Julie Jerber et al. NATURE GENETICS
- Genome-wide enhancer maps link risk variants to disease genes
- (2021) Joseph Nasser et al. NATURE
- Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells
- (2020) Xiaohu Wang et al. IMMUNITY
- Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci
- (2020) Maria Gutierrez-Arcelus et al. NATURE GENETICS
- Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression
- (2020) Anna S. E. Cuomo et al. Nature Communications
- Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants
- (2020) Margaret K. R. Donovan et al. Nature Communications
- Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines
- (2020) Eddie Cano-Gamez et al. Nature Communications
- Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses
- (2020) Chris Wallace PLoS Genetics
- Cell type–specific genetic regulation of gene expression across human tissues
- (2020) Sarah Kim-Hellmuth et al. SCIENCE
- Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation
- (2020) Dafni A. Glinos et al. GENES AND IMMUNITY
- The single-cell transcriptional landscape of mammalian organogenesis
- (2019) Junyue Cao et al. NATURE
- Epigenetic programming underpins B cell dysfunction in human SLE
- (2019) Christopher D. Scharer et al. NATURE IMMUNOLOGY
- Dynamic genetic regulation of gene expression during cellular differentiation
- (2019) B. J. Strober et al. SCIENCE
- Landscape of stimulation-responsive chromatin across diverse human immune cells
- (2019) Diego Calderon et al. NATURE GENETICS
- Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases
- (2019) Blagoje Soskic et al. NATURE GENETICS
- A Bayesian framework for multiple trait colocalization from summary association statistics
- (2018) Claudia Giambartolomei et al. BIOINFORMATICS
- Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors
- (2018) Laleh Haghverdi et al. NATURE BIOTECHNOLOGY
- Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs
- (2018) Monique G. P. van der Wijst et al. NATURE GENETICS
- Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response
- (2018) Kaur Alasoo et al. NATURE GENETICS
- Phase 2 Trial of Selective Tyrosine Kinase 2 Inhibition in Psoriasis
- (2018) Kim Papp et al. NEW ENGLAND JOURNAL OF MEDICINE
- Flexible statistical methods for estimating and testing effects in genomic studies with multiple conditions
- (2018) Sarah M. Urbut et al. NATURE GENETICS
- STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
- (2018) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
- (2018) Annalisa Buniello et al. NUCLEIC ACIDS RESEARCH
- Quantifying the regulatory effect size ofcis-acting genetic variation using allelic fold change
- (2017) Pejman Mohammadi et al. GENOME RESEARCH
- Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
- (2017) Florence Demenais et al. NATURE GENETICS
- Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types
- (2017) Sung Chun et al. NATURE GENETICS
- Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
- (2017) Manuel A Ferreira et al. NATURE GENETICS
- Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
- (2017) Katrina M de Lange et al. NATURE GENETICS
- Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
- (2017) Yuan Tian et al. Nature Communications
- Massively parallel digital transcriptional profiling of single cells
- (2017) Grace X. Y. Zheng et al. Nature Communications
- The Human Cell Atlas
- (2017) Aviv Regev et al. eLife
- Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells
- (2016) Lu Chen et al. CELL
- Interrupting CD28 costimulation before antigen rechallenge affects CD8+T-cell expansion and effector functions during secondary response in mice
- (2016) Monika Fröhlich et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)
- (2016) Jacqueline MacArthur et al. NUCLEIC ACIDS RESEARCH
- Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity
- (2016) C. A. Dendrou et al. Science Translational Medicine
- Influence ofTYK2in systemic sclerosis susceptibility: a newlocusin the IL-12 pathway
- (2015) Elena López-Isac et al. ANNALS OF THE RHEUMATIC DISEASES
- Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells
- (2015) Monika S. Kowalczyk et al. GENOME RESEARCH
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
- (2015) Suna Onengut-Gumuscu et al. NATURE GENETICS
- Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
- (2015) James Bentham et al. NATURE GENETICS
- Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma
- (2015) Sagar Lonial et al. NEW ENGLAND JOURNAL OF MEDICINE
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits
- (2015) Dorothée Diogo et al. PLoS One
- Dengue virus infection elicits highly polarized CX3CR1+cytotoxic CD4+T cells associated with protective immunity
- (2015) Daniela Weiskopf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
- (2015) Heather J. Cordell et al. Nature Communications
- Understanding the CD28/CTLA-4 (CD152) Pathway and Its Implications for Costimulatory Blockade
- (2014) D. Gardner et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Genetic and epigenetic fine mapping of causal autoimmune disease variants
- (2014) Kyle Kai-How Farh et al. NATURE
- Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations
- (2014) Desirée Schubert et al. NATURE MEDICINE
- Intersection of population variation and autoimmunity genetics in human T cell activation
- (2014) C. J. Ye et al. SCIENCE
- Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
- (2014) B. P. Fairfax et al. SCIENCE
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
- (2013) Adrian Cortes et al. NATURE GENETICS
- Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
- (2013) Ashley H Beecham et al. NATURE GENETICS
- Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis
- (2013) Anne Hinks et al. NATURE GENETICS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
- (2012) Steve Eyre et al. NATURE GENETICS
- Chromatin marks identify critical cell types for fine mapping complex trait variants
- (2012) Gosia Trynka et al. NATURE GENETICS
- Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
- (2012) Lam C Tsoi et al. NATURE GENETICS
- Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease
- (2011) Gosia Trynka et al. NATURE GENETICS
- Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4
- (2011) O. S. Qureshi et al. SCIENCE
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- Abatacept in the treatment of rheumatoid arthritis
- (2008) Maya H Buch et al. ARTHRITIS RESEARCH & THERAPY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now