Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types
出版年份 2017 全文链接
标题
Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types
作者
关键词
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出版物
NATURE GENETICS
Volume 49, Issue 4, Pages 600-605
出版商
Springer Nature
发表日期
2017-02-21
DOI
10.1038/ng.3795
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Colocalization of GWAS and eQTL Signals Detects Target Genes
- (2016) Farhad Hormozdiari et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Detection and interpretation of shared genetic influences on 42 human traits
- (2016) Joseph K Pickrell et al. NATURE GENETICS
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci
- (2015) Gosia Trynka et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Dominant Genetic Variation and Missing Heritability for Human Complex Traits: Insights from Twin versus Genome-wide Common SNP Models
- (2015) Xu Chen et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases
- (2015) H. Guo et al. HUMAN MOLECULAR GENETICS
- Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls
- (2015) Mary D Fortune et al. NATURE GENETICS
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants
- (2015) R. Malik et al. NEUROLOGY
- Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases
- (2014) Alexander Gusev et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Identifying Causal Variants at Loci with Multiple Signals of Association
- (2014) F. Hormozdiari et al. GENETICS
- Genetic and epigenetic fine mapping of causal autoimmune disease variants
- (2014) Kyle Kai-How Farh et al. NATURE
- Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes
- (2014) T. Raj et al. SCIENCE
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies
- (2014) Gleb Kichaev et al. PLoS Genetics
- Sherlock: Detecting Gene-Disease Associations by Matching Patterns of Expression QTL and GWAS
- (2013) Xin He et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Transcriptome and genome sequencing uncovers functional variation in humans
- (2013) Tuuli Lappalainen et al. NATURE
- Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
- (2013) Ashley H Beecham et al. NATURE GENETICS
- Pleiotropy in complex traits: challenges and strategies
- (2013) Nadia Solovieff et al. NATURE REVIEWS GENETICS
- Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes
- (2012) Chris Wallace et al. HUMAN MOLECULAR GENETICS
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Chromatin marks identify critical cell types for fine mapping complex trait variants
- (2012) Gosia Trynka et al. NATURE GENETICS
- Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
- (2012) M. T. Maurano et al. SCIENCE
- HAPGEN2: simulation of multiple disease SNPs
- (2011) Zhan Su et al. BIOINFORMATICS
- Pervasive Sharing of Genetic Effects in Autoimmune Disease
- (2011) Chris Cotsapas et al. PLoS Genetics
- The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study
- (2011) Alexandra C. Nica et al. PLoS Genetics
- GCTA: A Tool for Genome-wide Complex Trait Analysis
- (2010) Jian Yang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- The NIH Roadmap Epigenomics Mapping Consortium
- (2010) Bradley E Bernstein et al. NATURE BIOTECHNOLOGY
- Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations
- (2010) Alexandra C. Nica et al. PLoS Genetics
- Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS
- (2010) Dan L. Nicolae et al. PLoS Genetics
- Using gene expression to investigate the genetic basis of complex disorders
- (2008) A. C. Nica et al. HUMAN MOLECULAR GENETICS
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