Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
出版年份 2017 全文链接
标题
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
作者
关键词
-
出版物
NATURE GENETICS
Volume 49, Issue 2, Pages 256-261
出版商
Springer Nature
发表日期
2017-01-10
DOI
10.1038/ng.3760
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
- (2016) David Ellinghaus et al. NATURE GENETICS
- Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells
- (2016) David R Withers et al. NATURE MEDICINE
- Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity
- (2016) C. A. Dendrou et al. Science Translational Medicine
- Fast and efficient QTL mapper for thousands of molecular phenotypes
- (2015) Halit Ongen et al. BIOINFORMATICS
- Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation
- (2015) John J. Worthington et al. IMMUNITY
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
- (2015) Jimmy Z Liu et al. NATURE GENETICS
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- Mongersen, an Oral SMAD7 Antisense Oligonucleotide, and Crohn’s Disease
- (2015) Giovanni Monteleone et al. NEW ENGLAND JOURNAL OF MEDICINE
- Migration of Myeloid Cells during Inflammation Is Differentially Regulated by the Cell Surface Receptors Slamf1 and Slamf8
- (2015) Guoxing Wang et al. PLoS One
- Efficient haplotype matching and storage using the positional Burrows-Wheeler transform (PBWT)
- (2014) R. Durbin BIOINFORMATICS
- The Treatment-Naive Microbiome in New-Onset Crohn’s Disease
- (2014) Dirk Gevers et al. Cell Host & Microbe
- A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis
- (2014) Antonio Julià et al. HUMAN MOLECULAR GENETICS
- Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial
- (2014) Séverine Vermeire et al. LANCET
- Focused specificity of intestinal TH17 cells towards commensal bacterial antigens
- (2014) Yi Yang et al. NATURE
- A general framework for estimating the relative pathogenicity of human genetic variants
- (2014) Martin Kircher et al. NATURE GENETICS
- Identification of genetic variants associated with alternative splicing using sQTLseekeR
- (2014) Jean Monlong et al. Nature Communications
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- TGF-β Activation and Function in Immunity
- (2013) Mark A. Travis et al. Annual Review of Immunology
- Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals
- (2013) A. Battle et al. GENOME RESEARCH
- Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations
- (2013) Suk-Kyun Yang et al. GUT
- Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis
- (2013) Brian G. Feagan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease
- (2013) William J. Sandborn et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Hypermorphic Missense Mutation in PLCG2 , Encoding Phospholipase Cγ2, Causes a Dominantly Inherited Autoinflammatory Disease with Immunodeficiency
- (2012) Qing Zhou et al. AMERICAN JOURNAL OF HUMAN GENETICS
- optiCall: a robust genotype-calling algorithm for rare, low-frequency and common variants
- (2012) T. S. Shah et al. BIOINFORMATICS
- A Genome-Wide Association Study Identifies 2 Susceptibility Loci for Crohn's Disease in a Japanese Population
- (2012) Keiko Yamazaki et al. GASTROENTEROLOGY
- Phospholipase C 2 Plays a Role in TCR Signal Transduction and T Cell Selection
- (2012) G. Fu et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Slamf8 Is a Negative Regulator of Nox2 Activity in Macrophages
- (2012) G. Wang et al. JOURNAL OF IMMUNOLOGY
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Bayesian refinement of association signals for 14 loci in 3 common diseases
- (2012) Julian B Maller et al. NATURE GENETICS
- Cold Urticaria, Immunodeficiency, and Autoimmunity Related toPLCG2Deletions
- (2012) Michael J. Ombrello et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ustekinumab Induction and Maintenance Therapy in Refractory Crohn's Disease
- (2012) William J. Sandborn et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Genome-Wide Scan of Ashkenazi Jewish Crohn's Disease Suggests Novel Susceptibility Loci
- (2012) Eimear E. Kenny et al. PLoS Genetics
- Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
- (2011) Carl A Anderson et al. NATURE GENETICS
- RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota
- (2011) Shinichiro Sawa et al. NATURE IMMUNOLOGY
- Efalizumab, a Human Monoclonal Anti-CD11a Antibody, in the Treatment of Moderate to Severe Crohn’s Disease: An Open-Label Pilot Study
- (2010) Dustin G. James et al. DIGESTIVE DISEASES AND SCIENCES
- A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40phox and selective defects in neutrophil NADPH oxidase activity
- (2009) J. D. Matute et al. BLOOD
- Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project
- (2009) Kenneth R Carson et al. LANCET ONCOLOGY
- Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort
- (2008) R L Roberts et al. GENES AND IMMUNITY
- Bayes factors for genome-wide association studies: comparison withP-values
- (2008) Jon Wakefield GENETIC EPIDEMIOLOGY
- Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin
- (2008) Carmelo Luci et al. NATURE IMMUNOLOGY
- PID: the Pathway Interaction Database
- (2008) Carl F. Schaefer et al. NUCLEIC ACIDS RESEARCH
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