标题
A kinase-cGAS cascade to synthesize a therapeutic STING activator
作者
关键词
-
出版物
NATURE
Volume 603, Issue 7901, Pages 439-444
出版商
Springer Science and Business Media LLC
发表日期
2022-03-17
DOI
10.1038/s41586-022-04422-9
参考文献
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- (2021) Aaron L. Featherston et al. SCIENCE
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- (2021) Xinkun Ren et al. Current Opinion in Green and Sustainable Chemistry
- Synthetic Biochemistry: The Bio-inspired Cell-Free Approach to Commodity Chemical Production
- (2020) James U. Bowie et al. TRENDS IN BIOTECHNOLOGY
- Emerging strategies for expanding the toolbox of enzymes in biocatalysis
- (2020) Braddock A. Sandoval et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Novel Applications of Biocatalysis to Stereochemistry Determination of 2′3′-cGAMP Bisphosphorothioate (2′3′-cGSASMP)
- (2020) Jongwon Lim et al. ACS Omega
- Complete biosynthesis of cannabinoids and their unnatural analogues in yeast
- (2019) Xiaozhou Luo et al. NATURE
- The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes
- (2019) Ge Qu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Design of an in vitro biocatalytic cascade for the manufacture of islatravir
- (2019) Mark A. Huffman et al. SCIENCE
- DNA-induced liquid phase condensation of cGAS activates innate immune signaling
- (2018) Mingjian Du et al. SCIENCE
- Unlocking P(V): Reagents for chiral phosphorothioate synthesis
- (2018) Kyle W. Knouse et al. SCIENCE
- Design, Synthesis, and Biological Evaluation of Novel Cyclic Adenosine–Inosine Monophosphate (cAIMP) Analogs That Activate Stimulator of Interferon Genes (STING)
- (2016) Thierry Lioux et al. JOURNAL OF MEDICINAL CHEMISTRY
- Solid-Phase Synthesis of Oligonucleotide 5′-(α-P-Thio)triphosphates and 5′-(α-P-Thio)(β,γ-methylene)triphosphates
- (2014) Yann Thillier et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs
- (2014) Lingyin Li et al. Nature Chemical Biology
- Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA
- (2013) Pu Gao et al. CELL
- Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
- (2013) Pu Gao et al. CELL
- Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
- (2013) Xu Zhang et al. MOLECULAR CELL
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
- (2013) Elie J. Diner et al. Cell Reports
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- One-Flask Syntheses of c-di-GMP and the [Rp,Rp] and [Rp,Sp] Thiophosphate Analogues
- (2010) Barbara L. Gaffney et al. ORGANIC LETTERS
- NMR Chemical Shifts of Trace Impurities: Common Laboratory Solvents, Organics, and Gases in Deuterated Solvents Relevant to the Organometallic Chemist
- (2010) Gregory R. Fulmer et al. ORGANOMETALLICS
- Synthesis and immunostimulatory properties of the phosphorothioate analogues of cdiGMP
- (2008) Hongbin Yan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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