标题
Catalytic asymmetric and stereodivergent oligonucleotide synthesis
作者
关键词
-
出版物
SCIENCE
Volume 371, Issue 6530, Pages 702-707
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2021-02-12
DOI
10.1126/science.abf4359
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Enantiodivergent Formation of C–P Bonds: Synthesis of P-Chiral Phosphines and Methyl-phosphonate Oligonucleotides
- (2020) Dongmin Xu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Novel Applications of Biocatalysis to Stereochemistry Determination of 2′3′-cGAMP Bisphosphorothioate (2′3′-cGSASMP)
- (2020) Jongwon Lim et al. ACS Omega
- Asymmetric Catalysis Mediated by Synthetic Peptides, Version 2.0: Expansion of Scope and Mechanisms
- (2020) Anthony J. Metrano et al. CHEMICAL REVIEWS
- Disparate Catalytic Scaffolds for Atroposelective Cyclodehydration
- (2019) Yongseok Kwon et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Stereocontrolled Synthesis of Boranophosphate DNA by an Oxazaphospholidine Approach and Evaluation of Its Properties
- (2019) Rintaro Iwata Hara et al. JOURNAL OF ORGANIC CHEMISTRY
- Site-Selective Acylation of Natural Products with BINOL-Derived Phosphoric Acids
- (2019) Junqi Li et al. ACS Catalysis
- Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective
- (2019) Han Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Disulfide-Bridged Peptides That Mediate Enantioselective Cycloadditions through Thiyl Radical Catalysis
- (2018) Jonathan M. Ryss et al. ORGANIC LETTERS
- Unlocking P(V): Reagents for chiral phosphorothioate synthesis
- (2018) Kyle W. Knouse et al. SCIENCE
- Phosphothreonine (pThr)-Based Multifunctional Peptide Catalysis for Asymmetric Baeyer–Villiger Oxidations of Cyclobutanones
- (2018) Aaron L. Featherston et al. ACS Catalysis
- Stereodivergence in Asymmetric Catalysis
- (2017) Simon Krautwald et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
- (2017) Naoki Iwamoto et al. NATURE BIOTECHNOLOGY
- Synthesis and antibacterial activity of 5′-tetrachlorophthalimido and 5′-azido 5′-deoxyribonucleosides
- (2017) Robert Van Ostrand et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- A multifunctional catalyst that stereoselectively assembles prodrugs
- (2017) Daniel A. DiRocco et al. SCIENCE
- Recent Trends in Nucleotide Synthesis
- (2016) Béatrice Roy et al. CHEMICAL REVIEWS
- Applications and stereoselective syntheses of P-chirogenic phosphorus compounds
- (2016) Mathieu Dutartre et al. CHEMICAL SOCIETY REVIEWS
- Design, Synthesis, and Biological Evaluation of Novel Cyclic Adenosine–Inosine Monophosphate (cAIMP) Analogs That Activate Stimulator of Interferon Genes (STING)
- (2016) Thierry Lioux et al. JOURNAL OF MEDICINAL CHEMISTRY
- Phosphorothioate anti-sense oligonucleotides: the kinetics and mechanism of the generation of the sulfurising agent from phenylacetyl disulfide (PADS)
- (2016) James L. Scotson et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Phosphothreonine as a Catalytic Residue in Peptide-Mediated Asymmetric Transfer Hydrogenations of 8-Aminoquinolines
- (2015) Christopher R. Shugrue et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enantioselective Halogenative Semi-Pinacol Rearrangement: Extension of Substrate Scope and Mechanistic Investigations
- (2015) Fedor Romanov-Michailidis et al. CHEMISTRY-A EUROPEAN JOURNAL
- Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates
- (2014) Dixit Parmar et al. CHEMICAL REVIEWS
- Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs
- (2014) Lingyin Li et al. Nature Chemical Biology
- (3′-5′)-Cyclic Dinucleotides: Synthetic Strategies and Biological Potential
- (2013) Pascale Clivio et al. CHEMICAL REVIEWS
- Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases
- (2013) Lars Petter Jordheim et al. NATURE REVIEWS DRUG DISCOVERY
- Enantioselective Organocatalytic Iodination-Initiated Wagner–Meerwein Rearrangement
- (2013) Fedor Romanov-Michailidis et al. ORGANIC LETTERS
- An Approach to the Site-Selective Deoxygenation of Hydroxy Groups Based on Catalytic Phosphoramidite Transfer
- (2012) Peter A. Jordan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Reactive intermediates in the H-phosphonate synthesis of oligonucleotides
- (2012) Nicholas Powles et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- A General Preparation of Protected Phosphoamino Acids
- (2012) Daniel E. Petrillo et al. ORGANIC LETTERS
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- A convenient synthesis of the cytidyl 3′-terminal monomer for solid-phase synthesis of RNG oligonucleotides
- (2012) Ahmed M. Awad et al. TETRAHEDRON LETTERS
- Peptide Coupling Reagents, More than a Letter Soup
- (2011) Ayman El-Faham et al. CHEMICAL REVIEWS
- Enantioselective Synthesis of Highly Substituted Furans by a Copper(II)-Catalyzed Cycloisomerization–Indole Addition Reaction
- (2011) Vivek Rauniyar et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- A New Biarylphosphine Ligand for the Pd-Catalyzed Synthesis of Diaryl Ethers under Mild Conditions
- (2011) Luca Salvi et al. ORGANIC LETTERS
- One-Flask Syntheses of c-di-GMP and the [Rp,Rp] and [Rp,Sp] Thiophosphate Analogues
- (2010) Barbara L. Gaffney et al. ORGANIC LETTERS
- NMR Chemical Shifts of Trace Impurities: Common Laboratory Solvents, Organics, and Gases in Deuterated Solvents Relevant to the Organometallic Chemist
- (2010) Gregory R. Fulmer et al. ORGANOMETALLICS
- Asymmetric phosphorylation through catalytic P(III) phosphoramidite transfer: Enantioselective synthesis of D-myo-inositol-6-phosphate
- (2010) P. A. Jordan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Asymmetric Syntheses of l,l-and l,d-Di-myo-inositol-1,1′-phosphate and their Behavior as Stabilizers of Enzyme Activity at Extreme Temperatures
- (2009) Christina M. Longo et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- De-racemization of Enantiomers versus De-epimerization of Diastereomers-Classification of Dynamic Kinetic Asymmetric Transformations (DYKAT)
- (2008) Johannes Steinreiber et al. CHEMISTRY-A EUROPEAN JOURNAL
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
- The mechanism of the phosphoramidite synthesis of polynucleotides
- (2008) Mark A. Russell et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Efficient catalyst turnover in the phosphitylation of alcohols with phosphoramidites
- (2008) Patrick B. Brady et al. TETRAHEDRON LETTERS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started