Tocotrienol-Rich Fraction Modulates Amyloid Pathology and Improves Cognitive Function in AβPP/PS1 Mice

High Plasma Levels of Vitamin E Forms and Reduced Alzheimer's Disease Risk in Advanced Age

(2017) Francesca Mangialasche et al.   JOURNAL OF ALZHEIMERS DISEASE

Vitamin E therapy beyond cancer: Tocopherol versus tocotrienol

(2016) Hong Yong Peh et al.   PHARMACOLOGY & THERAPEUTICS

Is amyloid-β harmful to the brain? Insights from human imaging studies

(2015) William Jagust   BRAIN

Long-Term Vitamin E-Deficient Mice Exhibit Cognitive Dysfunction via Elevation of Brain Oxidation

(2015) Koji FUKUI et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

The case for rejecting the amyloid cascade hypothesis

(2015) Karl Herrup   NATURE NEUROSCIENCE

Curcumin derivative with the substitution at C-4 position, but not curcumin, is effective against amyloid pathology in APP/PS1 mice

(2015) Daijiro Yanagisawa et al.   NEUROBIOLOGY OF AGING

Donepezil improves learning and memory deficits in APP/PS1 mice by inhibition of microglial activation

(2015) H.B. Guo et al.   NEUROSCIENCE

CART treatment improves memory and synaptic structure in APP/PS1 mice

(2015) Jia-li Jin et al.   Scientific Reports

Organotypic vibrosections from whole brain adult Alzheimer mice (overexpressing amyloid-precursor-protein with the Swedish-Dutch-Iowa mutations) as a model to study clearance of beta-amyloid plaques

(2015) Christian Humpel   Frontiers in Aging Neuroscience

The neuroprotective effects of tocotrienol rich fraction and alpha tocopherol against glutamate injury in astrocytes

(2015) Thilaga Rati Selvaraju et al.   Bosnian Journal of Basic Medical Sciences

Nutrition and neurodegeneration: epidemiological evidence and challenges for future research

(2015) Sophie Gillette-Guyonnet et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Tocotrienol-Rich Fraction (TRF) Suppresses the Growth of Human Colon Cancer Xenografts in Balb/C Nude Mice by the Wnt Pathway

(2015) Jing-Shu Zhang et al.   PLoS One

Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease

(2014) Maurice W. Dysken et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effects of Vitamin E on Cognitive Performance during Ageing and in Alzheimer’s Disease

(2014) Giorgio Fata et al.   Nutrients

Longitudinal Amyloid Imaging in Mouse Brain with 11C-PIB: Comparison of APP23, Tg2576, and APPswe-PS1dE9 Mouse Models of Alzheimer Disease

(2013) A. Snellman et al.   JOURNAL OF NUCLEAR MEDICINE

Palm Oil–Derived Natural Vitamin E α-Tocotrienol in Brain Health and Disease

(2013) Chandan K Sen et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Biochemistry of Amyloid  -Protein and Amyloid Deposits in Alzheimer Disease

(2013) C. L. Masters et al.   Cold Spring Harbor Perspectives in Medicine

Do tocotrienols have potential as neuroprotective dietary factors?

(2011) Jan Frank et al.   AGEING RESEARCH REVIEWS

Linking lipids to Alzheimer's disease: cholesterol and beyond

(2011) Gilbert Di Paolo et al.   NATURE REVIEWS NEUROSCIENCE

Tocopherols and tocotrienols plasma levels are associated with cognitive impairment

(2011) Francesca Mangialasche et al.   NEUROBIOLOGY OF AGING

Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study

(2011) Siok-Fong Chin et al.   Nutrition & Metabolism

Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits

(2010) Daniel Jardanhazi-Kurutz et al.   NEUROCHEMISTRY INTERNATIONAL

Alpha-tocopherol quinone inhibits beta-amyloid aggregation and cytotoxicity, disaggregates preformed fibrils and decreases the production of reactive oxygen species, NO and inflammatory cytokines

(2010) Shi-gao Yang et al.   NEUROCHEMISTRY INTERNATIONAL

Structure-neurotoxicity relationships of amyloid  -protein oligomers

(2009) K. Ono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA