标题
The case for rejecting the amyloid cascade hypothesis
作者
关键词
-
出版物
NATURE NEUROSCIENCE
Volume 18, Issue 6, Pages 794-799
出版商
Springer Nature
发表日期
2015-05-26
DOI
10.1038/nn.4017
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease
- (2014) Sergio T. Ferreira et al. Alzheimers & Dementia
- Microglial dysfunction in brain aging and Alzheimer's disease
- (2014) Kira Irving Mosher et al. BIOCHEMICAL PHARMACOLOGY
- Pittsburgh compound B retention and progression of cognitive status - a meta-analysis
- (2014) X. Chen et al. EUROPEAN JOURNAL OF NEUROLOGY
- Pathways to Alzheimer's disease
- (2014) J. Hardy et al. JOURNAL OF INTERNAL MEDICINE
- The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease
- (2014) Tara L. Spires-Jones et al. NEURON
- Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease
- (2014) Stephen Salloway et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease
- (2014) Rachelle S. Doody et al. NEW ENGLAND JOURNAL OF MEDICINE
- Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models
- (2014) Scott J. Webster et al. Frontiers in Genetics
- Designing drug trials for Alzheimer’s disease: What we have learned from the release of the phase III antibody trials: A report from the EU/US/CTAD Task Force
- (2013) Bruno Vellas et al. Alzheimers & Dementia
- 2013 Alzheimer's disease facts and figures
- (2013) Alzheimers & Dementia
- The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
- (2013) Russell H. Swerdlow et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Metabolic Stress Modulates Alzheimer’s β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons
- (2013) Ruishan Wang et al. Cell Metabolism
- DNA-repair in mild cognitive impairment and Alzheimer's disease
- (2013) Nina Bucholtz et al. DNA REPAIR
- The role of ATM and DNA damage in neurons: Upstream and downstream connections
- (2013) Karl Herrup et al. DNA REPAIR
- The role of DNA repair in brain related disease pathology
- (2013) Chandrika Canugovi et al. DNA REPAIR
- Insulin, cognition, and dementia
- (2013) Brenna Cholerton et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Regulatable transgenic mouse models of Alzheimer disease: onset, reversibility and spreading of Tau pathology
- (2013) Katja Hochgräfe et al. FEBS Journal
- Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study
- (2013) Victor L Villemagne et al. LANCET NEUROLOGY
- The Senescence Hypothesis of Disease Progression in Alzheimer Disease: an Integrated Matrix of Disease Pathways for FAD and SAD
- (2013) Sally Hunter et al. MOLECULAR NEUROBIOLOGY
- Normal cognition in transgenic BRI2-Aβ mice
- (2013) Jungsu Kim et al. Molecular Neurodegeneration
- Alzheimer disease in the United States (2010-2050) estimated using the 2010 census
- (2013) L. E. Hebert et al. NEUROLOGY
- The Genetics of Alzheimer Disease
- (2013) R. E. Tanzi Cold Spring Harbor Perspectives in Medicine
- Animal Models of Alzheimer Disease
- (2013) F. M. LaFerla et al. Cold Spring Harbor Perspectives in Medicine
- The genetics and neuropathology of Alzheimer’s disease
- (2012) Gerard D. Schellenberg et al. ACTA NEUROPATHOLOGICA
- Oxidative stress increases BACE1 protein levels through activation of the PKR-eIF2α pathway
- (2012) François Mouton-Liger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Transgenic Mouse Models of Alzheimer Disease: Developing a Better Model as a Tool for Therapeutic Interventions
- (2012) Masashi Kitazawa et al. CURRENT PHARMACEUTICAL DESIGN
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
- (2012) Thorlakur Jonsson et al. NATURE
- Deciphering the mechanism underlying late-onset Alzheimer disease
- (2012) Dimitrije Krstic et al. Nature Reviews Neurology
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Reisa A. Sperling et al. Alzheimers & Dementia
- The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Guy M. McKhann et al. Alzheimers & Dementia
- Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease
- (2011) Victor L. Villemagne et al. ANNALS OF NEUROLOGY
- Autophagy failure in Alzheimer's disease—locating the primary defect
- (2011) Ralph A. Nixon et al. NEUROBIOLOGY OF DISEASE
- The pathological process underlying Alzheimer’s disease in individuals under thirty
- (2010) Heiko Braak et al. ACTA NEUROPATHOLOGICA
- Selective Cell Death of Hyperploid Neurons in Alzheimer’s Disease
- (2010) Thomas Arendt et al. AMERICAN JOURNAL OF PATHOLOGY
- Beneficial effect of human anti-amyloid-β active immunization on neurite morphology and tau pathology
- (2010) Alberto Serrano-Pozo et al. BRAIN
- The dysregulation of intracellular calcium in Alzheimer disease
- (2010) Charlene Supnet et al. CELL CALCIUM
- Calcium, ischemia and excitotoxicity
- (2010) Kinga Szydlowska et al. CELL CALCIUM
- Calcium Signaling and Amyloid Toxicity in Alzheimer Disease
- (2010) Angelo Demuro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Reimagining Alzheimer's Disease--An Age-Based Hypothesis
- (2010) K. Herrup JOURNAL OF NEUROSCIENCE
- Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
- (2010) Jorge J Palop et al. NATURE NEUROSCIENCE
- Can Alzheimer disease be prevented by amyloid-β immunotherapy?
- (2010) Cynthia A. Lemere et al. Nature Reviews Neurology
- The Genetics of Alzheimer Disease: Back to the Future
- (2010) Lars Bertram et al. NEURON
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Synaptic degeneration in Alzheimer’s disease
- (2009) Thomas Arendt ACTA NEUROPATHOLOGICA
- DNA Damage and Repair in Alzheimers Disease
- (2009) Fabio Coppede et al. Current Alzheimer Research
- Aneuploidy in the normal, Alzheimer's disease and ataxia-telangiectasia brain: Differential expression and pathological meaning
- (2009) Ivan Y. Iourov et al. NEUROBIOLOGY OF DISEASE
- Inflammation, microglia, and alzheimer's disease
- (2009) Brent Cameron et al. NEUROBIOLOGY OF DISEASE
- Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
- (2009) J. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Calcium dysregulation in Alzheimer's disease: From mechanisms to therapeutic opportunities
- (2009) Jin-Tai Yu et al. PROGRESS IN NEUROBIOLOGY
- Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship
- (2008) Peter T. Nelson et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- A Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease
- (2008) N. H. Varvel et al. JOURNAL OF NEUROSCIENCE
- Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
- (2008) Clive Holmes et al. LANCET
- Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
- (2008) Ganesh M Shankar et al. NATURE MEDICINE
- Animal models of Alzheimer's disease and frontotemporal dementia
- (2008) Jürgen Götz et al. NATURE REVIEWS NEUROSCIENCE
- DNA base excision repair activities in mouse models of Alzheimer's disease
- (2008) Lior Weissman et al. NEUROBIOLOGY OF AGING
- Linking Calcium to Aβ and Alzheimer's Disease
- (2008) Kim N. Green et al. NEURON
- Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
- (2008) Ilya Bezprozvanny et al. TRENDS IN NEUROSCIENCES
- Alzheimer's presenilin 1 causes chromosome missegregation and aneuploidy
- (2006) Debrah I. Boeras et al. NEUROBIOLOGY OF AGING
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started