Preclinical animal models of mental illnesses to translate findings from the bench to the bedside: Molecular brain mechanisms and peripheral biomarkers associated to early life stress or immune challenges

The effects of maternal separation on behaviours under social-housing environments in adult male C57BL/6 mice

(2021) Nozomi Endo et al.   Scientific Reports

Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

(2021) Plinio C. Casarotto et al.   CELL

Poly (I:C)-induced maternal immune activation modifies ventral hippocampal regulation of stress reactivity: prevention by environmental enrichment

(2021) Xin Zhao et al.   BRAIN BEHAVIOR AND IMMUNITY

Interaction of maternal immune activation and genetic interneuronal inhibition

(2021) Allison Anderson et al.   BRAIN RESEARCH

Use and abuse of dissociative and psychedelic drugs in adolescence

(2021) M.L. Shawn Bates et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Estrogen Receptor β as a Candidate Regulator of Sex Differences in the Maternal Immune Activation Model of ASD

(2021) Madeline L. Arnold et al.   Frontiers in Molecular Neuroscience

Schizophrenia and Influenza at the Centenary of the 1918-1919 Spanish Influenza Pandemic: Mechanisms of Psychosis Risk

(2020) Adrianna P. Kępińska et al.   Frontiers in Psychiatry

Microglial Function in the Effects of Early-Life Stress on Brain and Behavioral Development

(2020) Clarissa Catale et al.   Journal of Clinical Medicine

Baseline immunoreactivity before pregnancy and poly(I:C) dose combine to dictate susceptibility and resilience of offspring to maternal immune activation

(2020) Myka L. Estes et al.   BRAIN BEHAVIOR AND IMMUNITY

Gestational poly(I:C) attenuates, not exacerbates, the behavioral, cytokine and mTOR changes caused by isolation rearing in a rat ‘dual-hit’ model for neurodevelopmental disorders

(2020) Jen-Yin Goh et al.   BRAIN BEHAVIOR AND IMMUNITY

Alterations in ‘inflammatory’ pathways in the rat prefrontal cortex as early biological predictors of the long-term negative consequences of exposure to stress early in life

(2020) Nicola Lopizzo et al.   PSYCHONEUROENDOCRINOLOGY

Gestational Factors throughout Fetal Neurodevelopment: The Serotonin Link

(2020) Sabrina I. Hanswijk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prenatal Stress Impairs Postnatal Learning and Memory Development via Disturbance of the cGMP–PKG Pathway and Oxidative Phosphorylation in the Hippocampus of Rats

(2020) Yu-jie Li et al.   Frontiers in Molecular Neuroscience

Interferon-γ signaling in human iPSC–derived neurons recapitulates neurodevelopmental disorder phenotypes

(2020) Katherine Warre-Cornish et al.   Science Advances

Maternal immune activation in rats attenuates the excitability of monoamine-secreting neurons in adult offspring in a sex-specific way

(2020) Kristina Csatlosova et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Behavioral, neuroanatomical, and molecular correlates of resilience and susceptibility to maternal immune activation

(2020) Flavia S. Mueller et al.   MOLECULAR PSYCHIATRY

Effects of chronic unpredictable mild stress induced prenatal stress on neurodevelopment of neonates: Role of GSK-3β

(2019) Mahino Fatima et al.   Scientific Reports

Transcriptional Signatures of Cognitive Impairment in Rat Exposed to Prenatal Stress

(2019) Annamaria Cattaneo et al.   MOLECULAR NEUROBIOLOGY

Deficiencies of microglia and TNFα in the mPFC-mediated cognitive inflexibility induced by social stress during adolescence

(2019) Yu Zhang et al.   BRAIN BEHAVIOR AND IMMUNITY

The critical importance of basic animal research for neuropsychiatric disorders

(2019) Tracy L. Bale et al.   NEUROPSYCHOPHARMACOLOGY

Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury

(2019) Suvi Pöyhönen et al.   Frontiers in Physiology

Born this way: Hippocampal neurogenesis across the lifespan

(2019) Danka A. Kozareva et al.   AGING CELL

The maternal immune activation model uncovers a role for the Arx gene in GABAergic dysfunction in schizophrenia

(2019) Jay P. Nakamura et al.   BRAIN BEHAVIOR AND IMMUNITY

From early adversities to immune activation in psychiatric disorders: the role of the sympathetic nervous system

(2019) Valeria Mondelli et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Implications from early life stress on the development of mouse ovarian follicles: Focus on oxidative stress

(2019) Mina Ghatebi et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Biphasic Impact of Prenatal Inflammation and Macrophage Depletion on the Wiring of Neocortical Inhibitory Circuits

(2019) Morgane Sonia Thion et al.   Cell Reports

Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation

(2019) Nadine Provençal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal viral infection causes global alterations in porcine fetal microglia

(2019) Adrienne M. Antonson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurodevelopmental Resilience and Susceptibility to Maternal Immune Activation

(2019) Urs Meyer   TRENDS IN NEUROSCIENCES

Challenges and opportunities of a-priori and a-posteriori variability in maternal immune activation models

(2019) Ulrike Weber-Stadlbauer et al.   Current Opinion in Behavioral Sciences

Adolescent maturation of the prefrontal cortex: Role of stress and sex in shaping adult risk for compromise

(2019) Gladys A. Shaw et al.   GENES BRAIN AND BEHAVIOR

Animal models of major depression: drawbacks and challenges

(2019) Barbara Planchez et al.   JOURNAL OF NEURAL TRANSMISSION

Transcriptional and epigenetic changes of brain derived neurotrophic factor following prenatal stress: A systematic review of animal studies

(2019) Negin Badihian et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Positron Emission Tomography Studies of the Glial Cell Marker Translocator Protein in Patients With Psychosis: A Meta-analysis Using Individual Participant Data

(2018) Pontus Plavén-Sigray et al.   BIOLOGICAL PSYCHIATRY

Neurobiology and consequences of social isolation stress in animal model—A comprehensive review

(2018) Faiza Mumtaz et al.   BIOMEDICINE & PHARMACOTHERAPY

Mouse models of maternal immune activation: Mind your caging system!

(2018) Flavia S. Mueller et al.   BRAIN BEHAVIOR AND IMMUNITY

Effect of prenatal stress on ɑ5 GABA A receptor subunit gene expression in hippocampus and pilocarpine induced seizure in rats

(2018) Mehrdad Nejatbakhsh et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Maternal Interleukin-6 concentration during pregnancy is associated with variation in frontolimbic white matter and cognitive development in early life

(2018) Jerod M. Rasmussen et al.   NEUROIMAGE

Dynamic changes in hippocampal microglia contribute to depressive-like behavior induced by early social isolation

(2018) Yu Gong et al.   NEUROPHARMACOLOGY

Prenatal exposure to environmental insults and enhanced risk of developing Schizophrenia and Autism Spectrum Disorder: Focus on biological pathways and epigenetic mechanisms

(2018) Nadia Cattane et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

A novel adolescent chronic social defeat model: reverse-Resident-Intruder Paradigm (rRIP) in male rats

(2018) Kevin M. Manz et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Maternal Vitamin D Prevents Abnormal Dopaminergic Development and Function in a Mouse Model of Prenatal Immune Activation

(2018) Wei Luan et al.   Scientific Reports

The Impact and Mechanism of Methylated Metabotropic Glutamate Receptors 1 and 5 in the Hippocampus on Depression-Like Behavior in Prenatal Stress Offspring Rats

(2018) Tianwei Lin et al.   Journal of Clinical Medicine

Inside the Developing Brain to Understand Teen Behavior From Rat Models: Metabolic, Structural, and Functional-Connectivity Alterations Among Limbic Structures Across Three Pre-adolescent Stages

(2018) Francesca Zoratto et al.   Frontiers in Behavioral Neuroscience

Effects of Maternal Deprivation and Complex Housing on Rat Social Behavior in Adolescence and Adulthood

(2018) Jiska Kentrop et al.   Frontiers in Behavioral Neuroscience

On the role of corticosterone in behavioral disorders, microbiota composition alteration and neuroimmune response in adult male mice subjected to maternal separation stress

(2018) Hossein Amini-Khoei et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Brain changes in a maternal immune activation model of neurodevelopmental brain disorders

(2018) Lara Bergdolt et al.   PROGRESS IN NEUROBIOLOGY

Neuroinflammation in schizophrenia: meta-analysis of in vivo microglial imaging studies

(2018) Tiago Reis Marques et al.   PSYCHOLOGICAL MEDICINE

Increasing Role of Maternal Immune Activation in Neurodevelopmental Disorders

(2018) Julie Boulanger-Bertolus et al.   Frontiers in Behavioral Neuroscience

Parental Infections Before, During, and After Pregnancy as Risk Factors for Mental Disorders in Childhood and Adolescence: A Nationwide Danish Study

(2018) Cecilie N. Lydholm et al.   BIOLOGICAL PSYCHIATRY

Changes in brain metabolites related to stress resilience: Metabolomic analysis of the hippocampus in a rat model of depression

(2018) Hayato Akimoto et al.   BEHAVIOURAL BRAIN RESEARCH

Chronic lurasidone treatment normalizes GABAergic marker alterations in the dorsal hippocampus of mice exposed to prenatal immune activation

(2017) A. Luoni et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

CASPR2 autoantibodies are raised during pregnancy in mothers of children with mental retardation and disorders of psychological development but not autism

(2017) Ester Coutinho et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia

(2017) T Notter et al.   MOLECULAR PSYCHIATRY

Maternal Immune Activation Causes Behavioral Impairments and Altered Cerebellar Cytokine and Synaptic Protein Expression

(2017) Gurudutt Pendyala et al.   NEUROPSYCHOPHARMACOLOGY

Early-life adversity and brain development: Is the microbiome a missing piece of the puzzle?

(2017) S.M. O’Mahony et al.   NEUROSCIENCE

Epigenetic Alterations and Prenatal Maternal Depression

(2017) Zsofia Nemoda et al.   Birth Defects Research

Maternal separation facilitates extinction of social fear in adult male mice

(2016) Iulia Zoicas et al.   BEHAVIOURAL BRAIN RESEARCH

Early life stress perturbs the maturation of microglia in the developing hippocampus

(2016) Jean-Christophe Delpech et al.   BRAIN BEHAVIOR AND IMMUNITY

Maternal separation activates microglial cells and induces an inflammatory response in the hippocampus of male rat pups, independently of hypothalamic and peripheral cytokine levels

(2016) Angélica Roque et al.   BRAIN BEHAVIOR AND IMMUNITY

Animal Models of Maternal Immune Activation in Depression Research

(2016) Marianne Ronovsky et al.   Current Neuropharmacology

Expression and alternative splicing of classical and nonclassical MHCI genes in the hippocampus and neuromuscular junction

(2016) Mazell M. Tetruashvily et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Effects of prenatal Poly I:C exposure on global histone deacetylase (HDAC) and DNA methyltransferase (DNMT) activity in the mouse brain

(2016) Yara Pujol Lopez et al.   MOLECULAR BIOLOGY REPORTS

Transgenerational transmission and modification of pathological traits induced by prenatal immune activation

(2016) U Weber-Stadlbauer et al.   MOLECULAR PSYCHIATRY

Long-term effects of early life stress exposure: Role of epigenetic mechanisms

(2016) Dafne M. Silberman et al.   PHARMACOLOGICAL RESEARCH

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness

(2016) Marilia A. Calcia et al.   PSYCHOPHARMACOLOGY

Maternal immune activation: Implications for neuropsychiatric disorders

(2016) M. L. Estes et al.   SCIENCE

Chronic social isolation decreases glutamate and glutamine levels and induces oxidative stress in the rat hippocampus

(2015) Yuan Shao et al.   BEHAVIOURAL BRAIN RESEARCH

Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders

(2015) Pierluca Coiro et al.   BRAIN BEHAVIOR AND IMMUNITY

Programming the Brain and Behaviour by Early-Life Stress: A Focus on Neuroactive Steroids

(2015) P. J. Brunton   JOURNAL OF NEUROENDOCRINOLOGY

Modeling psychiatric disorders for developing effective treatments

(2015) Tobias Kaiser et al.   NATURE MEDICINE

MicroRNAs as biomarkers of resilience or vulnerability to stress

(2015) R.J. Chen et al.   NEUROSCIENCE

Changes in Astroglial Markers in a Maternal Immune Activation Model of Schizophrenia in Wistar Rats are Dependent on Sex

(2015) Daniela F. de Souza et al.   Frontiers in Cellular Neuroscience

Prenatal exposure to noise stress: Anxiety, impaired spatial memory, and deteriorated hippocampal plasticity in postnatal life

(2014) Marzieh Barzegar et al.   HIPPOCAMPUS

Long-lasting recognition memory impairment and alterations in brain levels of cytokines and BDNF induced by maternal deprivation: effects of valproic acid and topiramate

(2014) Rose Mary Carvalho Pinheiro et al.   JOURNAL OF NEURAL TRANSMISSION

Prenatal maternal factors in the development of cognitive impairments in the offspring

(2014) Juliet Richetto et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The organization of the stress system and its dysregulation in depressive illness

(2014) P W Gold   MOLECULAR PSYCHIATRY

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

(2014) Yang Zhan et al.   NATURE NEUROSCIENCE

Microglial phagocytosis of live neurons

(2014) Guy C. Brown et al.   NATURE REVIEWS NEUROSCIENCE

Perspectives on neuroinflammation and excitotoxicity: A neurotoxic conspiracy?

(2014) Barbara Viviani et al.   NEUROTOXICOLOGY

Epigenetic Upregulation of Corticotrophin-Releasing Hormone Mediates Postnatal Maternal Separation-Induced Memory Deficiency

(2014) Aiyun Wang et al.   PLoS One

Rodent Models of Depression: Neurotrophic and Neuroinflammatory Biomarkers

(2014) Mikhail Stepanichev et al.   Biomed Research International

Peripubertal stress-induced behavioral changes are associated with altered expression of genes involved in excitation and inhibition in the amygdala

(2014) S Tzanoulinou et al.   Translational Psychiatry

Effects of early life adverse experiences on the brain: implications from maternal separation models in rodents

(2014) Mayumi Nishi et al.   Frontiers in Neuroscience

Early-Life Stress, HPA Axis Adaptation, and Mechanisms Contributing to Later Health Outcomes

(2014) Jayanthi Maniam et al.   Frontiers in Endocrinology

Prenatal Stress Affects Network Properties of Rat Hippocampal Neurons

(2013) Gayane Grigoryan et al.   BIOLOGICAL PSYCHIATRY

Social Isolation Exacerbates Schizophrenia-Like Phenotypes via Oxidative Stress in Cortical Interneurons

(2013) Zhihong Jiang et al.   BIOLOGICAL PSYCHIATRY

Prenatal Poly(I:C) Exposure and Other Developmental Immune Activation Models in Rodent Systems

(2013) Urs Meyer   BIOLOGICAL PSYCHIATRY

Microglial Dysregulation in Psychiatric Disease

(2013) Luciana Romina Frick et al.   Clinical & Developmental Immunology

Prolonged maternal separation disturbs the serotonergic system during early brain development

(2013) Ken-ichi Ohta et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Oxidative Stress and Neurodegenerative Disorders

(2013) Jie Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Does Breastfeeding Result in Smarter Children? A Closer LookBelfortMBRifas-ShimanSLKleinmanKPGuthrieLBBellingerDCTaverasEMGillmanMWOkenE. Infant feeding and childhood cognition at ages 3 and 7 years: effects of breastfeeding duration and exclusivity [published online July29, 2013]. JAMA Pediatr. doi:10.1001/jamapediatrics.2013.455.

(2013) Donna J. Chapman   JOURNAL OF HUMAN LACTATION

Maternal Immune Activation Increases the Corticosterone Response to Acute Stress without Affecting the Hypothalamic Monoamine Content and Sleep Patterns in Male Mice Offspring

(2013) Adriano Zager et al.   NEUROIMMUNOMODULATION

GABAergic Interneurons Shape the Functional Maturation of the Cortex

(2013) Corentin Le Magueresse et al.   NEURON

Altered GSK3β signaling in an infection-based mouse model of developmental neuropsychiatric disease

(2013) Roman Willi et al.   NEUROPHARMACOLOGY

Role of Social Encounter-Induced Activation of Prefrontal Serotonergic Systems in the Abnormal Behaviors of Isolation-Reared Mice

(2013) Yukio Ago et al.   NEUROPSYCHOPHARMACOLOGY

Maternal inflammation promotes fetal microglial activation and increased cholinergic expression in the fetal basal forebrain: role of interleukin-6

(2013) Lorelei Pratt et al.   PEDIATRIC RESEARCH

Prenatal Immune Activation Induces Maturation-Dependent Alterations in the Prefrontal GABAergic Transcriptome

(2013) Juliet Richetto et al.   SCHIZOPHRENIA BULLETIN

Maternal deprivation in the middle of a stress hyporesponsive period decreases hippocampal calcineurin expression and causes abnormal social and cognitive behaviours in adult male Wistar rats: Relevance to negative symptoms of schizophrenia

(2012) Kenkichi Takase et al.   BEHAVIOURAL BRAIN RESEARCH

Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response

(2012) Devon B. Oskvig et al.   BRAIN BEHAVIOR AND IMMUNITY

Prenatal stress increases the expression of proinflammatory cytokines and exacerbates the inflammatory response to LPS in the hippocampal formation of adult male mice

(2012) Yolanda Diz-Chaves et al.   BRAIN BEHAVIOR AND IMMUNITY

Early-life stress-induced anxiety-related behavior in adult mice partially requires forebrain corticotropin-releasing hormone receptor 1

(2012) Xiao-Dong Wang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Early repeated maternal separation induces alterations of hippocampus reelin expression in rats

(2012) Jianlong Zhang et al.   JOURNAL OF BIOSCIENCES

Maternal Deprivation in Rats is Associated with Corticotrophin-Releasing Hormone (CRH) Promoter Hypomethylation and Enhances CRH Transcriptional Responses to Stress in Adulthood

(2012) J. Chen et al.   JOURNAL OF NEUROENDOCRINOLOGY

Early maternal separation leads to down-regulation of cytokine gene expression

(2012) J. J. Dimatelis et al.   METABOLIC BRAIN DISEASE

REST-dependent epigenetic remodeling promotes the developmental switch in synaptic NMDA receptors

(2012) Alma Rodenas-Ruano et al.   NATURE NEUROSCIENCE

Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents

(2012) Ronald S. Duman et al.   TRENDS IN NEUROSCIENCES

Placental TNF-α Signaling in Illness-Induced Complications of Pregnancy

(2011) Pamela A. Carpentier et al.   AMERICAN JOURNAL OF PATHOLOGY

Abnormal Trajectories of Neurodevelopment and Behavior Following In Utero Insult in the Rat

(2011) Yael Piontkewitz et al.   BIOLOGICAL PSYCHIATRY

Cbln family proteins promote synapse formation by regulating distinct neurexin signaling pathways in various brain regions

(2011) Keiko Matsuda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Early Life Stress Enhances Angiotensin II–Mediated Vasoconstriction by Reduced Endothelial Nitric Oxide Buffering Capacity

(2011) Analia S. Loria et al.   HYPERTENSION

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

(2011) Maurizio Popoli et al.   NATURE REVIEWS NEUROSCIENCE

Gender-dependent behavioral and biochemical effects of adolescent delta-9-tetrahydrocannabinol in adult maternally deprived rats

(2011) E. Zamberletti et al.   NEUROSCIENCE

Within-litter variation in maternal care received by individual pups correlates with adolescent social play behavior in male rats

(2011) F.N. van Hasselt et al.   PHYSIOLOGY & BEHAVIOR

Social defeat stress in rats: escalation of cocaine and “speedball” binge self-administration, but not heroin

(2011) Fabio C. Cruz et al.   PSYCHOPHARMACOLOGY

Microglial activation in a neuroinflammational animal model of schizophrenia — a pilot study

(2011) Georg Juckel et al.   SCHIZOPHRENIA RESEARCH

Alcohol during adolescence selectively alters immediate and long-term behavior and neurochemistry

(2010) Antoniette M. Maldonado-Devincci et al.   ALCOHOL

Epigenetic Transmission of the Impact of Early Stress Across Generations

(2010) Tamara B. Franklin et al.   BIOLOGICAL PSYCHIATRY

Pubertal maturation and programming of hypothalamic–pituitary–adrenal reactivity

(2010) Russell D. Romeo   FRONTIERS IN NEUROENDOCRINOLOGY

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

Early Adolescence as a Critical Window During Which Social Stress Distinctly Alters Behavior and Brain Norepinephrine Activity

(2010) Brian Bingham et al.   NEUROPSYCHOPHARMACOLOGY

Early-life stress and antidepressants modulate peripheral biomarkers in a gene–environment rat model of depression

(2010) Lucia Carboni et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Early life stress impairs social recognition due to a blunted response of vasopressin release within the septum of adult male rats

(2010) Michael Lukas et al.   PSYCHONEUROENDOCRINOLOGY

Cbln1 Is a Ligand for an Orphan Glutamate Receptor  2, a Bidirectional Synapse Organizer

(2010) K. Matsuda et al.   SCIENCE

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Age matters

(2009) James Edgar McCutcheon et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Behavioural and Neurochemical Consequences of Early Weaning in Rodents

(2009) T. Kikusui et al.   JOURNAL OF NEUROENDOCRINOLOGY

Maternal separation alters nerve growth factor and corticosterone levels but not the DNA methylation status of the exon 17 glucocorticoid receptor promoter region

(2009) W. M. U. Daniels et al.   METABOLIC BRAIN DISEASE

Effects of stress throughout the lifespan on the brain, behaviour and cognition

(2009) Sonia J. Lupien et al.   NATURE REVIEWS NEUROSCIENCE

Pre-pubertal stress exposure affects adult behavioral response in association with changes in circulating corticosterone and brain-derived neurotrophic factor

(2009) Noam Bazak et al.   PSYCHONEUROENDOCRINOLOGY

Are animal models predictive for humans?

(2009) Niall Shanks et al.   Philosophy Ethics and Humanities in Medicine

Deficient maternal care resulting from immunological stress during pregnancy is associated with a sex-dependent enhancement of conditioned fear in the offspring

(2008) Severin Schwendener et al.   Journal of Neurodevelopmental Disorders

Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia

(2008) E Romero et al.   MOLECULAR PSYCHIATRY

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE

Why do many psychiatric disorders emerge during adolescence?

(2008) Tomáš Paus et al.   NATURE REVIEWS NEUROSCIENCE

Preliminary evidence for a modulation of fetal dopaminergic development by maternal immune activation during pregnancy

(2008) U. Meyer et al.   NEUROSCIENCE

Implications of the DSM's emphasis on sadness and anhedonia in major depressive disorder

(2008) Julia D. Buckner et al.   PSYCHIATRY RESEARCH

Effects of chronic social stress in adolescence on anxiety and neuroendocrine response to mild stress in male and female rats

(2007) C MCCORMICK et al.   BEHAVIOURAL BRAIN RESEARCH

Early-life infection leads to altered BDNF and IL-1β mRNA expression in rat hippocampus following learning in adulthood

(2007) Staci D. Bilbo et al.   BRAIN BEHAVIOR AND IMMUNITY