Maternal viral infection causes global alterations in porcine fetal microglia

Long-term Risk of Neuropsychiatric Disease After Exposure to Infection In Utero

(2019) Benjamin J. S. al-Haddad et al.   JAMA Psychiatry

Controversies and prospects about microglia in maternal immune activation models for neurodevelopmental disorders

(2018) Silke Smolders et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered Hippocampal Gene Expression and Morphology in Fetal Piglets following Maternal Respiratory Viral Infection

(2018) Adrienne M. Antonson et al.   DEVELOPMENTAL NEUROSCIENCE

Regulatory Effects of Neuroinflammatory Responses Through Brain-Derived Neurotrophic Factor Signaling in Microglial Cells

(2018) Sheng-Wei Lai et al.   MOLECULAR NEUROBIOLOGY

Sex differences in neuroimmunity as an inherent risk factor

(2018) Margaret M. McCarthy   NEUROPSYCHOPHARMACOLOGY

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development

(2018) Ilia D. Vainchtein et al.   SCIENCE

Fast prenatal development of the NPY neuron system in the neocortex of the European wild boar, Sus scrofa

(2018) Laura Ernst et al.   Brain Structure & Function

Microglia extensively survey the developing cortex via the CXCL12/CXCR4 system to help neural progenitors to acquire differentiated properties

(2018) Yuki Hattori et al.   GENES TO CELLS

Maternal immune activation: reporting guidelines to improve the rigor, reproducibility, and transparency of the model

(2018) Amanda C. Kentner et al.   NEUROPSYCHOPHARMACOLOGY

Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity

(2017) Richa Hanamsagar et al.   GLIA

Staining of HLA-DR, Iba1 and CD68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology

(2017) Debbie A.E. Hendrickx et al.   JOURNAL OF NEUROIMMUNOLOGY

Social impairments in autism spectrum disorder are related to maternal immune history profile

(2017) S Patel et al.   MOLECULAR PSYCHIATRY

Reversing behavioural abnormalities in mice exposed to maternal inflammation

(2017) Yeong Shin Yim et al.   NATURE

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring

(2017) Sangdoo Kim et al.   NATURE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Maternal inflammation induces immune activation of fetal microglia and leads to disrupted microglia immune responses, behavior, and learning performance in adulthood

(2017) Wandert Schaafsma et al.   NEUROBIOLOGY OF DISEASE

Microglia in CNS development: Shaping the brain for the future

(2017) Coralie-Anne Mosser et al.   PROGRESS IN NEUROBIOLOGY

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

(2017) Katharine Askew et al.   Cell Reports

Diffusion tensor MR imaging characteristics of cerebral white matter development in fetal pigs

(2017) Wenxu Qi et al.   BMC MEDICAL IMAGING

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment

(2017) D Mattei et al.   Translational Psychiatry

Crystallins and neuroinflammation: The glial side of the story

(2016) Jennifer E. Dulle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Peripheral viral infection induced microglial sensome genes and enhanced microglial cell activity in the hippocampus of neonatal piglets

(2016) Peng Ji et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglia across the lifespan: from origin to function in brain development, plasticity and cognition

(2016) Tuan Leng Tay et al.   JOURNAL OF PHYSIOLOGY-LONDON

Deficient autophagy in microglia impairs synaptic pruning and causes social behavioral defects

(2016) H-J Kim et al.   MOLECULAR PSYCHIATRY

Sall1 is a transcriptional regulator defining microglia identity and function

(2016) Anne Buttgereit et al.   NATURE IMMUNOLOGY

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal immune activation: Implications for neuropsychiatric disorders

(2016) M. L. Estes et al.   SCIENCE

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

(2016) G. B. Choi et al.   SCIENCE

Microglia development follows a stepwise program to regulate brain homeostasis

(2016) O. Matcovitch-Natan et al.   SCIENCE

Commentary: Maternal immune activation evoked by polyinosinic: polycytidylic acid does not evoke microglial cell activation in the embryo

(2016) Hans-Gert Bernstein et al.   Frontiers in Cellular Neuroscience

CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory

(2016) Miou Zhou et al.   eLife

Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice

(2015) Paola A. Spadaro et al.   BIOLOGICAL PSYCHIATRY

Therapeutic Targets for Neurodevelopmental Disorders Emerging from Animal Models with Perinatal Immune Activation

(2015) Daisuke Ibi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo

(2015) Silke Smolders et al.   Frontiers in Cellular Neuroscience

Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains

(2015) Douglas G. Walker et al.   Alzheimers Research & Therapy

The Domestic Piglet: An Important Model for Investigating the Neurodevelopmental Consequences of Early Life Insults

(2015) Matthew S. Conrad et al.   Annual Review of Animal Biosciences

Dose-Dependent Effects of Lactobacillus rhamnosus on Serum Interleukin-17 Production and Intestinal T-Cell Responses in Pigs Challenged with Escherichia coli

(2014) Yao-Hong Zhu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The risk for behavioural deficits is determined by the maternal immune response to prenatal immune challenge in a neurodevelopmental model

(2014) S. Missault et al.   BRAIN BEHAVIOR AND IMMUNITY

The different effects of LPS and poly I:C prenatal immune challenges on the behavior, development and inflammatory responses in pregnant mice and their offspring

(2014) Dany Arsenault et al.   BRAIN BEHAVIOR AND IMMUNITY

The porcine innate immune system: An update

(2014) K.H. Mair et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Microglial regulation of immunological and neuroprotective functions of astroglia

(2014) Shih-Heng Chen et al.   GLIA

Respiratory Viral Infection in Neonatal Piglets Causes Marked Microglia Activation in the Hippocampus and Deficits in Spatial Learning

(2014) M. R. P. Elmore et al.   JOURNAL OF NEUROSCIENCE

Microglia Enhance Neurogenesis and Oligodendrogenesis in the Early Postnatal Subventricular Zone

(2014) Y. Shigemoto-Mogami et al.   JOURNAL OF NEUROSCIENCE

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

(2014) Yang Zhan et al.   NATURE NEUROSCIENCE

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex

(2014) Benedetta Arnò et al.   Nature Communications

Microglia Modulate Wiring of the Embryonic Forebrain

(2014) Paola Squarzoni et al.   Cell Reports

Activation of the Maternal Immune System During Pregnancy Alters Behavioral Development of Rhesus Monkey Offspring

(2013) Melissa D. Bauman et al.   BIOLOGICAL PSYCHIATRY

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Microglia Regulate the Number of Neural Precursor Cells in the Developing Cerebral Cortex

(2013) C. L. Cunningham et al.   JOURNAL OF NEUROSCIENCE

Layer V cortical neurons require microglial support for survival during postnatal development

(2013) Masaki Ueno et al.   NATURE NEUROSCIENCE

TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement

(2013) Allison R Bialas et al.   NATURE NEUROSCIENCE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

The microglial sensome revealed by direct RNA sequencing

(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

A quantitative magnetic resonance histology atlas of postnatal rat brain development with regional estimates of growth and variability

(2013) Evan Calabrese et al.   NEUROIMAGE

Maternal inflammation promotes fetal microglial activation and increased cholinergic expression in the fetal basal forebrain: role of interleukin-6

(2013) Lorelei Pratt et al.   PEDIATRIC RESEARCH

Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species

(2013) Bridgette D. Semple et al.   PROGRESS IN NEUROBIOLOGY

Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism

(2012) Natalia V. Malkova et al.   BRAIN BEHAVIOR AND IMMUNITY

CD4+ and γδTCR+ T lymphocytes are sources of interleukin-17 in swine

(2012) Hana Stepanova et al.   CYTOKINE

Brain Growth of the Domestic Pig(Sus scrofa)from 2 to 24 Weeks of Age: A Longitudinal MRI Study

(2012) Matthew S. Conrad et al.   DEVELOPMENTAL NEUROSCIENCE

TGF-β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment

(2012) Shai Abutbul et al.   GLIA

Complex invasion pattern of the cerebral cortex bymicroglial cells during development of the mouse embryo

(2012) Nina Swinnen et al.   GLIA

Sex, glia, and development: Interactions in health and disease

(2012) Jaclyn M. Schwarz et al.   HORMONES AND BEHAVIOR

Review: Activation patterns of microglia and their identification in the human brain

(2012) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

An Automated Method to Quantify Microglia Morphology and Application to Monitor Activation State Longitudinally In Vivo

(2012) Cleopatra Kozlowski et al.   PLoS One

Effects of maternal immune activation on gene expression patterns in the fetal brain

(2012) K A Garbett et al.   Translational Psychiatry

Molecular signals of plasticity at the tetrapartite synapse

(2011) Alexander Dityatev et al.   CURRENT OPINION IN NEUROBIOLOGY

CXCR3 in T cell function

(2011) Joanna R. Groom et al.   EXPERIMENTAL CELL RESEARCH

Progress in defining the biological causes of schizophrenia

(2011) Benjamin Pickard   EXPERT REVIEWS IN MOLECULAR MEDICINE

Nitric oxide regulates astrocyte maturation in the hippocampus: Involvement of NOS2

(2011) Catherine Béchade et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The viral theory of schizophrenia revisited: Abnormal placental gene expression and structural changes with lack of evidence for H1N1 viral presence in placentae of infected mice or brains of exposed offspring

(2011) S. Hossein Fatemi et al.   NEUROPHARMACOLOGY

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Reelin expression during embryonic development of the pig brain

(2010) Karsten B Nielsen et al.   BMC NEUROSCIENCE

Activation of the maternal immune system induces endocrine changes in the placenta via IL-6

(2010) Elaine Y. Hsiao et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

α-Crystallin Downregulates the Expression of TNF-α and iNOS by Activated Rat Retinal Microglia in vitro and in vivo

(2009) Nan Wu et al.   OPHTHALMIC RESEARCH