A GSH-depleted platinum(IV) prodrug triggers ferroptotic cell death in breast cancer

A carrier-free anti-inflammatory platinum (II) self-delivered nanoprodrug for enhanced breast cancer therapy

(2021) Lei Xing et al.   JOURNAL OF CONTROLLED RELEASE

Synergistic Platinum(II) Prodrug Nanoparticles for Enhanced Breast Cancer Therapy

(2020) Chen-Xi Yang et al.   MOLECULAR PHARMACEUTICS

Fenton reaction-independent ferroptosis therapy via glutathione and iron redox couple sequentially triggered lipid peroxide generator

(2020) Yu-Jing He et al.   BIOMATERIALS

A Hybrid Nanovector of Suicide Gene Engineered Lentivirus Coated with Bioreducible Polyaminoglycosides for Enhancing Therapeutic Efficacy against Glioma

(2019) Wenhua Fan et al.   ADVANCED FUNCTIONAL MATERIALS

Inhibition of breast cancer proliferation and metastasis by strengthening host immunity with a prolonged oxygen-generating phototherapy hydrogel

(2019) Tian-Jiao Zhou et al.   JOURNAL OF CONTROLLED RELEASE

Light triggered oxygen-affording engines for repeated hypoxia-resistant photodynamic therapy

(2019) Tian-Jiao Zhou et al.   JOURNAL OF CONTROLLED RELEASE

Amplification of tumor antigen presentation by NLGplatin to improve chemoimmunotherapy

(2019) Yong Zhu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Reactive oxygen species-responsive nanoprodrug with quinone methides-mediated GSH depletion for improved chlorambucil breast cancers therapy

(2018) Cheng-Qiong Luo et al.   JOURNAL OF CONTROLLED RELEASE

Ferroptosis: A Novel Anti-tumor Action for Cisplatin

(2018) Jipeng Guo et al.   Cancer Research and Treatment

Photoactivated platinum-based anticancer drugs

(2018) Muhammad Imran et al.   COORDINATION CHEMISTRY REVIEWS

Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy

(2018) Xiang Ling et al.   ACS Nano

Probing Ligand-Induced Cooperative Orbital Redistribution That Dominates Nanoscale Molecule–Surface Interactions with One-Unit-Thin TiO2 Nanosheets

(2018) Guolei Xiang et al.   NANO LETTERS

The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

(2016) Timothy C. Johnstone et al.   CHEMICAL REVIEWS

Cisplatin versus carboplatin: comparative review of therapeutic management in solid malignancies

(2016) Gwo Yaw Ho et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Chemical Approach to Positional Isomers of Glucose–Platinum Conjugates Reveals Specific Cancer Targeting through Glucose-Transporter-Mediated Uptake in Vitro and in Vivo

(2016) Malay Patra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Prodrug Platin-A: Simultaneous Release of Cisplatin and Aspirin

(2014) Rakesh K. Pathak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

The ligation of aspirin to cisplatin demonstrates significant synergistic effects on tumor cells

(2014) Qinqin Cheng et al.   CHEMICAL COMMUNICATIONS

Synthetic Methods for the Preparation of Platinum Anticancer Complexes

(2013) Justin J. Wilson et al.   CHEMICAL REVIEWS

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

The status of platinum anticancer drugs in the clinic and in clinical trials

(2010) Nial J. Wheate et al.   DALTON TRANSACTIONS

Self-immolative linkers in polymeric delivery systems

(2010) Christopher A. Blencowe et al.   Polymer Chemistry

Phase II Study of Carboplatin, Paclitaxel, and Bevacizumab With Maintenance Bevacizumab As First-Line Chemotherapy for Advanced Müllerian Tumors

(2009) Richard T. Penson et al.   JOURNAL OF CLINICAL ONCOLOGY