Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD
出版年份 2022 全文链接
标题
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD
作者
关键词
-
出版物
Autophagy
Volume -, Issue -, Pages 1-20
出版商
Informa UK Limited
发表日期
2022-04-27
DOI
10.1080/15548627.2022.2062887
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes
- (2021) Meysam Yazdankhah et al. Autophagy
- The role of autophagy in skin pigmentation
- (2021) Weidong Zhu et al. EUROPEAN JOURNAL OF DERMATOLOGY
- Oxidation inhibits autophagy protein deconjugation from phagosomes to sustain MHC class II restricted antigen presentation
- (2021) Laure-Anne Ligeon et al. Nature Communications
- βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity
- (2021) Sayan Ghosh et al. Communications Biology
- The Role of the Effects of Autophagy on NLRP3 Inflammasome in Inflammatory Nervous System Diseases
- (2021) Shizhen Zhao et al. Frontiers in Cell and Developmental Biology
- Integrated analysis of multimodal single-cell data
- (2021) Yuhan Hao et al. CELL
- Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C
- (2021) Ting-Ting Chu et al. NATURE
- STING inhibitors target the cyclic dinucleotide binding pocket
- (2021) Ze Hong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STING1 Promotes Ferroptosis Through MFN1/2-Dependent Mitochondrial Fusion
- (2021) Changfeng Li et al. Frontiers in Cell and Developmental Biology
- βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells
- (2021) Peng Shang et al. Communications Biology
- Implication of ferroptosis in aging
- (2021) Maryam Mazhar et al. Cell Death Discovery
- Lipocalin-2: Structure, function, distribution and role in metabolic disorders
- (2021) Saeeda Al Jaberi et al. BIOMEDICINE & PHARMACOTHERAPY
- The role of lipocalin-2 in age-related macular degeneration (AMD)
- (2020) Sayan Ghosh et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Quartz Dust Exposure Affects NLRP3 Inflammasome Activation and Plasma Levels of IL-18 and IL-1Ra in Iron Foundry Workers
- (2020) Alexander Hedbrant et al. MEDIATORS OF INFLAMMATION
- Ferroptosis: past, present and future
- (2020) Jie Li et al. Cell Death & Disease
- Membrane transport proteins in melanosomes: Regulation of ions for pigmentation
- (2020) Pattama Wiriyasermkul et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Ferroptosis and Its Potential Role in Human Diseases
- (2020) Chu Han et al. Frontiers in Pharmacology
- Biological Functions and Therapeutic Potential of Lipocalin 2 in Cancer
- (2020) Ginette S. Santiago-Sánchez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Enhanced Keap1-Nrf2/Trx-1 axis by daphnetin protects against oxidative stress-driven hepatotoxicity via inhibiting ASK1/JNK and Txnip/NLRP3 inflammasome activation
- (2020) Hongming Lv et al. PHYTOMEDICINE
- Microglia versus Monocytes: Distinct Roles in Degenerative Diseases of the Retina
- (2020) Chen Yu et al. TRENDS IN NEUROSCIENCES
- Interplay Between NLRP3 Inflammasome and Autophagy
- (2020) Monika Biasizzo et al. Frontiers in Immunology
- Loganin Attenuates High Glucose-Induced Schwann Cells Pyroptosis by Inhibiting ROS Generation and NLRP3 Inflammasome Activation
- (2020) Yu-Chi Cheng et al. Cells
- The Iron Tug-of-War between Bacterial Siderophores and Innate Immunity
- (2019) Rachel Golonka et al. Journal of Innate Immunity
- Ferroptosis is a type of autophagy-dependent cell death
- (2019) Borong Zhou et al. SEMINARS IN CANCER BIOLOGY
- Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration
- (2019) Rinki Ratnapriya et al. NATURE GENETICS
- Molecular hydrogen suppresses free radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction
- (2019) Katsuya Iuchi et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration
- (2019) James T. Handa et al. Nature Communications
- Impact of Autophagy and Aging on Iron Load and Ferritin in Drosophila Brain
- (2019) Anne-Claire Jacomin et al. Frontiers in Cell and Developmental Biology
- The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma
- (2019) Claudia Rehwald et al. BRITISH JOURNAL OF CANCER
- Insight into the mechanism of ferroptosis inhibition by ferrostatin-1
- (2019) Giovanni Miotto et al. Redox Biology
- Inflammation-induced behavioral changes is driven by alterations in Nrf2-dependent apoptosis and autophagy in mouse hippocampus: Role of fluoxetine
- (2019) Sayan Ghosh et al. CELLULAR SIGNALLING
- Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
- (2018) Mario Mauthe et al. Autophagy
- Mechanism and medical implications of mammalian autophagy
- (2018) Ivan Dikic et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration
- (2018) Jie Wang et al. Nature Communications
- Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis
- (2018) Shashank Masaldan et al. Redox Biology
- PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism
- (2018) Changfeng Li et al. DEVELOPMENTAL CELL
- Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells
- (2017) Kati Juuti-Uusitalo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Autophagy-regulating protease Atg4: structure, function, regulation and inhibition
- (2017) Tatsuro Maruyama et al. JOURNAL OF ANTIBIOTICS
- Lipocalin-2 (NGAL) Attenuates Autophagy to Exacerbate Cardiac Apoptosis Induced by Myocardial Ischemia
- (2017) Hye Kyoung Sung et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Activating the AKT2-nuclear factor-κB-lipocalin-2 axis elicits an inflammatory response in age-related macular degeneration
- (2017) Sayan Ghosh et al. JOURNAL OF PATHOLOGY
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- cGAS drives noncanonical-inflammasome activation in age-related macular degeneration
- (2017) Nagaraj Kerur et al. NATURE MEDICINE
- A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B
- (2017) N. Pengo et al. Nature Communications
- Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response
- (2017) Vijay K. Gonugunta et al. Cell Reports
- Inflammasome-dependent IL-1β release depends upon membrane permeabilisation
- (2016) F Martín-Sánchez et al. CELL DEATH AND DIFFERENTIATION
- Lipocalin-2 inhibits autophagy and induces insulin resistance in H9c2 cells
- (2016) Yee Kwan Chan et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- An Autophagic Flux Probe that Releases an Internal Control
- (2016) Takeshi Kaizuka et al. MOLECULAR CELL
- Disposal of iron by a mutant form of lipocalin 2
- (2016) Jonathan Barasch et al. Nature Communications
- Parainflammation, chronic inflammation, and age-related macular degeneration
- (2015) M. Chen et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome
- (2015) Bradley D. Gelfand et al. Cell Reports
- Increased Lipocalin-2 in the retinal pigment epithelium ofCryba1cKO mice is associated with a chronic inflammatory response
- (2014) Mallika Valapala et al. AGING CELL
- Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling
- (2014) Mallika Valapala et al. Autophagy
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Iron upregulates melanogenesis in cultured retinal pigment epithelial cells
- (2014) Natalie Wolkow et al. EXPERIMENTAL EYE RESEARCH
- Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
- (2014) Wan Ling Wong et al. Lancet Global Health
- The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer
- (2012) Subhankar Chakraborty et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Lipocalin-2 ameliorates granulocyte functionality
- (2012) Andrea Schroll et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
- (2012) Chong-Shan Shi et al. NATURE IMMUNOLOGY
- Bmp6 Regulates Retinal Iron Homeostasis and Has Altered Expression in Age-Related Macular Degeneration
- (2011) Majda Hadziahmetovic et al. AMERICAN JOURNAL OF PATHOLOGY
- Aceruloplasminemia
- (2011) Natalie Wolkow ARCHIVES OF OPHTHALMOLOGY
- Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis
- (2011) Paresh P. Chothe et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Lipocalin 2 deficiency inhibits cell proliferation, autophagy, and mitochondrial biogenesis in mouse embryonic cells
- (2011) Daozhong Jin et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Quantitation of protein-protein interactions by thermal stability shift analysis
- (2011) Curtis J. Layton et al. PROTEIN SCIENCE
- Lipocalin 2 is essential for chronic kidney disease progression in mice and humans
- (2010) Amandine Viau et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy is essential for mouse sense of balance
- (2010) Guillermo Mariño et al. JOURNAL OF CLINICAL INVESTIGATION
- IntracellularMycobacterium aviumIntersect Transferrin in the Rab11+Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway
- (2010) Øyvind Halaas et al. JOURNAL OF INFECTIOUS DISEASES
- Overview of Iron Chelation Therapy with Desferrioxamine and Deferiprone
- (2009) Maria D. Cappellini et al. HEMOGLOBIN
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started