Inflammasome-dependent IL-1β release depends upon membrane permeabilisation

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Formation of Disulfide Bridges Drives Oligomerization, Membrane Pore Formation, and Translocation of Fibroblast Growth Factor 2 to Cell Surfaces

(2015) Hans-Michael Müller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis

(2015) Sean P. Cullen et al.   Cell Reports

ATP-Induced IL-1β Specific Secretion: True Under Stringent Conditions

(2015) Monique Stoffels et al.   Frontiers in Immunology

Release of Interleukin-1α or Interleukin-1β Depends on Mechanism of Cell Death

(2014) Hazel England et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

(2014) Alberto Baroja-Mazo et al.   NATURE IMMUNOLOGY

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

(2014) Bernardo S Franklin et al.   NATURE IMMUNOLOGY

Real-time single-cell imaging of protein secretion

(2014) Yoshitaka Shirasaki et al.   Scientific Reports

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

(2014) Kaiwen W. Chen et al.   Cell Reports

The Interleukin-1 Family: Back to the Future

(2013) Cecilia Garlanda et al.   IMMUNITY

P2X7 receptor-stimulation causes fever via PGE2 and IL-1β release

(2012) Maria Barberà-Cremades et al.   FASEB JOURNAL

Cell Volume Regulation Modulates NLRP3 Inflammasome Activation

(2012) Vincent Compan et al.   IMMUNITY

Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P2)-dependent Oligomerization of Fibroblast Growth Factor 2 (FGF2) Triggers the Formation of a Lipidic Membrane Pore Implicated in Unconventional Secretion

(2012) Julia P. Steringer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Understanding the mechanism of IL-1β secretion

(2011) Gloria Lopez-Castejon et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Sterile inflammatory responses mediated by the NLRP3 inflammasome

(2010) Suzanne L. Cassel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tec-Kinase-Mediated Phosphorylation of Fibroblast Growth Factor 2 is Essential for Unconventional Secretion

(2010) Antje D. Ebert et al.   TRAFFIC

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

A novel flow cytometric assay to quantify interactions between proteins and membrane lipids

(2009) Koen Temmerman et al.   JOURNAL OF LIPID RESEARCH

Mechanisms of regulated unconventional protein secretion

(2009) Walter Nickel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Unconventional Mechanisms of Protein Transport to the Cell Surface of Eukaryotic Cells

(2008) Walter Nickel et al.   Annual Review of Cell and Developmental Biology

A Direct Role for Phosphatidylinositol-4,5-bisphosphate in Unconventional Secretion of Fibroblast Growth Factor 2

(2008) Koen Temmerman et al.   TRAFFIC