Phagosome maturation in macrophages: Eat, digest, adapt, and repeat

Better Together: Current Insights Into Phagosome-Lysosome Fusion

(2021) Jenny A. Nguyen et al.   Frontiers in Immunology

Modulation of Immune Responses by Particle Size and Shape

(2021) Maksim V. Baranov et al.   Frontiers in Immunology

Monitoring Phosphoinositide Fluxes and Effectors During Leukocyte Chemotaxis and Phagocytosis

(2021) Fernando Montaño-Rendón et al.   Frontiers in Cell and Developmental Biology

Origins, Biology, and Diseases of Tissue Macrophages

(2021) Nehemiah Cox et al.   Annual Review of Immunology

A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS

(2021) Mehran Najibi et al.   Autophagy

TPL‐2 kinase induces phagosome acidification to promote macrophage killing of bacteria

(2021) Felix Breyer et al.   EMBO JOURNAL

Beyond “Big Eaters”: The Versatile Role of Alveolar Macrophages in Health and Disease

(2021) Miriam Hetzel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tissue-resident macrophages: guardians of organ homeostasis

(2021) Samuel Philip Nobs et al.   TRENDS IN IMMUNOLOGY

Microbial Phagocytic Receptors and Their Potential Involvement in Cytokine Induction in Macrophages

(2021) Yan Lin Fu et al.   Frontiers in Immunology

Putting the brakes on phagocytosis: “don't‐eat‐me” signaling in physiology and disease

(2021) Shannon M Kelley et al.   EMBO REPORTS

The expanding world of tissue‐resident macrophages

(2021) Stephen J. Jenkins et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes

(2021) Charlene E. Lancaster et al.   JOURNAL OF CELL BIOLOGY

A Golgi-derived vesicle potentiates PtdIns4P to PtdIns3P conversion for endosome fission

(2021) Bo Gong et al.   NATURE CELL BIOLOGY

The Phagocytic Code Regulating Phagocytosis of Mammalian Cells

(2021) Tom O. J. Cockram et al.   Frontiers in Immunology

Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages

(2020) Yuning Lu et al.   IMMUNITY

Biting off what can be chewed: Trogocytosis in health, infection and disease

(2020) Akhila Bettadapur et al.   INFECTION AND IMMUNITY

F-actin flashes on phagosomes mechanically deform contents for efficient digestion in macrophages

(2020) Mathieu B. Poirier et al.   JOURNAL OF CELL SCIENCE

The clearance of dead cells by efferocytosis

(2020) Emilio Boada-Romero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

LRRK2 Is Recruited to Phagosomes and Co-recruits RAB8 and RAB10 in Human Pluripotent Stem Cell-Derived Macrophages

(2020) Heyne Lee et al.   Stem Cell Reports

Maintaining social contacts: The physiological relevance of organelle interactions

(2020) Beatriz S.C. Silva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Endosomal microdomains: Formation and function

(2020) Anne Norris et al.   CURRENT OPINION IN CELL BIOLOGY

Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation

(2020) Glenn F.W. Walpole et al.   Cell Reports

Qki is an essential regulator of microglial phagocytosis in demyelination

(2020) Jiangong Ren et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Salmonella and S. aureus Escape From the Clearance of Macrophages via Controlling TFEB

(2020) Shanshan Rao et al.   Frontiers in Microbiology

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

Mycobacterium tuberculosis infection of host cells in space and time

(2019) Claudio Bussi et al.   FEMS MICROBIOLOGY REVIEWS

Clearance by Microglia Depends on Packaging of Phagosomes into a Unique Cellular Compartment

(2019) Ambra Villani et al.   DEVELOPMENTAL CELL

SNX3 drives maturation of Borrelia phagosomes by forming a hub for PI(3)P, Rab5a, and galectin-9

(2019) Matthias Klose et al.   JOURNAL OF CELL BIOLOGY

Rab20 is critical for bacterial lipoprotein tolerization-enhanced bactericidal activity in macrophages during bacterial infection

(2019) Shuqi Zhao et al.   Science China-Life Sciences

Rab32 GTPase, as a direct target of miR-30b/c, controls the intracellular survival of Burkholderia pseudomallei by regulating phagosome maturation

(2019) Zhi-qiang Hu et al.   PLoS Pathogens

Innate Immune Recognition: An Issue More Complex Than Expected

(2019) Klara Kubelkova et al.   Frontiers in Cellular and Infection Microbiology

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

(2019) Marco Orecchioni et al.   Frontiers in Immunology

The Lysosome Signaling Platform: Adapting With the Times

(2019) Subothan Inpanathan et al.   Frontiers in Cell and Developmental Biology

Phosphoinositide switches in endocytosis and in the endolysosomal system

(2019) Haibin Wang et al.   CURRENT OPINION IN CELL BIOLOGY

Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling

(2019) Roni Levin-Konigsberg et al.   NATURE CELL BIOLOGY

The pattern recognition receptors dectin-2, mincle, and FcRγ impact the dynamics of phagocytosis of Candida, Saccharomyces, Malassezia, and Mucor species

(2019) Mohammed Haider et al.   PLoS One

Lysosome Fission: Planning for an Exit

(2019) Golam T. Saffi et al.   TRENDS IN CELL BIOLOGY

Restriction of intracellular Salmonella replication by restoring TFEB-mediated xenophagy

(2019) Veena Ammanathan et al.   Autophagy

The myotubularin MTMR4 regulates phagosomal phosphatidylinositol 3-phosphate turnover and phagocytosis

(2019) David A. Sheffield et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The functional universe of membrane contact sites

(2019) William A. Prinz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phagosome‐endoplasmic reticulum contacts: Kissing and not running

(2019) Roni Levin‐Konigsberg et al.   TRAFFIC

Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation

(2019) Victoria E. B. Hipolito et al.   PLOS BIOLOGY

Phagocytosis: What’s on the menu?

(2018) Charlene E. Lancaster et al.   Biochemistry and Cell Biology

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

(2018) Anetta Härtlova et al.   EMBO JOURNAL

Mesenchymal stem cells enhance NOX2-dependent reactive oxygen species production and bacterial killing in macrophages during sepsis

(2018) Razieh Rabani et al.   EUROPEAN RESPIRATORY JOURNAL

The role of lipids in host-pathogen interactions

(2018) Glenn F. W. Walpole et al.   IUBMB LIFE

Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence

(2018) Christopher H. Choy et al.   JOURNAL OF CELL SCIENCE

The enigmatic endosome – sorting the ins and outs of endocytic trafficking

(2018) Naava Naslavsky et al.   JOURNAL OF CELL SCIENCE

Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion

(2018) Andreas Jeschke et al.   MOLECULAR BIOLOGY OF THE CELL

Impact of the TAP-like transporter in antigen presentation and phagosome maturation

(2018) Myriam Lawand et al.   MOLECULAR IMMUNOLOGY

Phagocytosis of antibody-opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages

(2018) Ramraj Velmurugan et al.   TRAFFIC

Rethinking Phagocytes: Clues from the Retina and Testes

(2018) Kristen K. Penberthy et al.   TRENDS IN CELL BIOLOGY

Rab GTPase Function in Endosome and Lysosome Biogenesis

(2018) Lars Langemeyer et al.   TRENDS IN CELL BIOLOGY

Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation

(2018) Eva Maria Wenzel et al.   Nature Communications

Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes

(2018) Michelle E Maxson et al.   eLife

A Novel Class of ER Membrane Proteins Regulates ER-Associated Endosome Fission

(2018) Melissa J. Hoyer et al.   CELL

Mycobacterial PknG Targets the Rab7l1 Signaling Pathway To Inhibit Phagosome–Lysosome Fusion

(2018) Gourango Pradhan et al.   JOURNAL OF IMMUNOLOGY

PIKfyve accelerates phagosome acidification through activation of TRPML1 while arrests aberrant vacuolation independent of the Ca2+ channel

(2018) Yuri Isobe et al.   JOURNAL OF BIOCHEMISTRY

Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function

(2018) William McAlpine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of phagosome functions by post-translational modifications: a new paradigm

(2018) Paul Dean et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The lysosomal Ca2+release channel TRPML1 regulates lysosome size by activating calmodulin

(2017) Qi Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositide conversion in endocytosis and the endolysosomal system

(2017) Alexander Wallroth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

pH of endophagosomes controls association of their membranes with Vps34 and PtdIns(3)P levels

(2017) Amriya Naufer et al.   JOURNAL OF CELL BIOLOGY

Defects in ER–endosome contacts impact lysosome function in hereditary spastic paraplegia

(2017) Rachel Allison et al.   JOURNAL OF CELL BIOLOGY

Phosphoinositol 3-phosphate acts as a timer for reactive oxygen species production in the phagosome

(2017) Zhi Min Song et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis

(2017) Roni Levin et al.   MOLECULAR BIOLOGY OF THE CELL

How cells engulf: a review of theoretical approaches to phagocytosis

(2017) David M Richards et al.   REPORTS ON PROGRESS IN PHYSICS

PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes

(2017) Christin Bissig et al.   TRAFFIC

Patterns, Receptors, and Signals: Regulation of Phagosome Maturation

(2017) Anne-Marie Pauwels et al.   TRENDS IN IMMUNOLOGY

Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels

(2017) Luke C. Davies et al.   Nature Communications

STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells

(2017) Paula Nunes-Hasler et al.   Nature Communications

SNX10 promotes phagosome maturation in macrophages and protects mice against Listeria monocytogenes infection

(2017) Jun Lou et al.   Oncotarget

Maturation of phagosomes containing different erythrophagocytic particles in primary macrophages

(2017) Inês B. Santarino et al.   FEBS Open Bio

TFEB and TFE3: Linking Lysosomes to Cellular Adaptation to Stress

(2016) Nina Raben et al.   Annual Review of Cell and Developmental Biology

TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages

(2016) Nunzia Pastore et al.   Autophagy

Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease and cancer

(2016) R B Birge et al.   CELL DEATH AND DIFFERENTIATION

Phagocytosis Enhances Lysosomal and Bactericidal Properties by Activating the Transcription Factor TFEB

(2016) Matthew A. Gray et al.   CURRENT BIOLOGY

Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity

(2016) Nicholas A. Bright et al.   CURRENT BIOLOGY

PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment

(2016) Shefali Krishna et al.   DEVELOPMENTAL CELL

Phosphatidylinositol 3‐phosphates—at the interface between cell signalling and membrane traffic

(2016) Andrea L Marat et al.   EMBO JOURNAL

Rab22a controls MHC‐I intracellular trafficking and antigen cross‐presentation by dendritic cells

(2016) Ignacio Cebrian et al.   EMBO REPORTS

The life cycle of phagosomes: formation, maturation, and resolution

(2016) Roni Levin et al.   IMMUNOLOGICAL REVIEWS

Lysosomal trafficking regulator Lyst links membrane trafficking to toll-like receptor–mediated inflammatory responses

(2016) Andreas Westphal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rab32/38 and the xenophagic restriction of intracellular bacteria replication

(2016) Bor Luen Tang   MICROBES AND INFECTION

The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases

(2016) Hor-Yue Tan et al.   Oxidative Medicine and Cellular Longevity

WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors

(2016) Catherine M. Buckley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbe-inducible trafficking pathways that control Toll-like receptor signaling

(2016) Yunhao Tan et al.   TRAFFIC

Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis

(2016) Charles Yin et al.   Cell Death & Disease

An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense

(2016) Mehran Najibi et al.   Cell Reports

Detection and manipulation of phosphoinositides

(2015) Olof Idevall-Hagren et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Polyphosphoinositide binding domains: Key to inositol lipid biology

(2015) Gerald R.V. Hammond et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phosphoinositides in phagocytosis and macropinocytosis

(2015) Roni Levin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

ER-endosome contact sites: molecular compositions and functions

(2015) C. Raiborg et al.   EMBO JOURNAL

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus

(2015) S. Herbst et al.   EMBO Molecular Medicine

Rab14 Regulates Maturation of Macrophage Phagosomes Containing the Fungal Pathogen Candida albicans and Outcome of the Host-Pathogen Interaction

(2015) Blessing Okai et al.   INFECTION AND IMMUNITY

The role of Rab6 GTPase in the maturation of phagosome against Staphylococcus aureus

(2015) Yulei Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Phosphatidylinositol 4,5-Bisphosphate Homeostasis Regulated by Nir2 and Nir3 Proteins at Endoplasmic Reticulum-Plasma Membrane Junctions

(2015) Chi-Lun Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative Proteome Analysis of Temporally Resolved Phagosomes Following Uptake Via Key Phagocytic Receptors

(2015) Brian D. Dill et al.   MOLECULAR & CELLULAR PROTEOMICS

Structure and function of ER membrane contact sites with other organelles

(2015) Melissa J. Phillips et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis

(2015) Andreas Jeschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Phosphoinositide-Gated Lysosomal Ca2+Channel, TRPML1, Is Required for Phagosome Maturation

(2015) Roya M. Dayam et al.   TRAFFIC

ER-Coordinated Activities of Rab22a and Rab5a Drive Phagosomal Compaction and Intracellular Processing of Borrelia burgdorferi by Macrophages

(2015) Xenia Naj et al.   Cell Reports

Inpp5e increases the Rab5 association and phosphatidylinositol 3-phosphate accumulation at the phagosome through an interaction with Rab20

(2014) Tomohiro Segawa et al.   BIOCHEMICAL JOURNAL

Innate Host Defense Requires TFEB-Mediated Transcription of Cytoprotective and Antimicrobial Genes

(2014) Orane Visvikis et al.   IMMUNITY

Phagocytosis: receptors, signal integration, and the cytoskeleton

(2014) Spencer A. Freeman et al.   IMMUNOLOGICAL REVIEWS

Integrin  1 Regulates Phagosome Maturation in Macrophages through Rac Expression

(2014) Q.-Q. Wang et al.   JOURNAL OF IMMUNOLOGY

The chemotaxis of M1 and M2 macrophages is regulated by different chemokines

(2014) Wenjuan Xuan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Phagosome maturation in polarized macrophages

(2014) Johnathan Canton   JOURNAL OF LEUKOCYTE BIOLOGY

Contrasting phagosome pH regulation and maturation in human M1 and M2 macrophages

(2014) Johnathan Canton et al.   MOLECULAR BIOLOGY OF THE CELL

PIKfyve Inhibition Interferes with Phagosome and Endosome Maturation in Macrophages

(2014) Grace H.E. Kim et al.   TRAFFIC

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

(2013) Francesca Giordano et al.   CELL

A Rab-Centric Perspective of Bacterial Pathogen-Occupied Vacuoles

(2013) Racquel Kim Sherwood et al.   Cell Host & Microbe

A TRP Channel in the Lysosome Regulates Large Particle Phagocytosis via Focal Exocytosis

(2013) Mohammad Samie et al.   DEVELOPMENTAL CELL

Filamentous morphology of bacteria delays the timing of phagosome morphogenesis in macrophages

(2013) Akriti Prashar et al.   JOURNAL OF CELL BIOLOGY

mTOR regulates phagosome and entotic vacuole fission

(2013) Matej Krajcovic et al.   MOLECULAR BIOLOGY OF THE CELL

Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636

(2012) Diego Sbrissa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Superoxide Dismutase in Redox Biology: The Roles of Superoxide and Hydrogen Peroxide

(2012) Garry R. Buettner   Anti-Cancer Agents in Medicinal Chemistry

STIM1 Juxtaposes ER to Phagosomes, Generating Ca2+ Hotspots that Boost Phagocytosis

(2012) Paula Nunes et al.   CURRENT BIOLOGY

Essential roles of PIKfyve and PTEN on phagosomal phosphatidylinositol 3-phosphate dynamics

(2012) Kaoru Hazeki et al.   FEBS LETTERS

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation

(2012) Yueguang Rong et al.   NATURE CELL BIOLOGY

Rab20 Regulates Phagosome Maturation in RAW264 Macrophages during Fc Gamma Receptor-Mediated Phagocytosis

(2012) Youhei Egami et al.   PLoS One

Class IA Phosphatidylinositol 3-Kinase p110α Regulates Phagosome Maturation

(2012) Emily P. Thi et al.   PLoS One

In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P

(2012) S. N. Zolov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autonomous phagosomal degradation and antigen presentation in dendritic cells

(2012) E. Hoffmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HOPS Proteins hVps41 and hVps39 Are Required for Homotypic and Heterotypic Late Endosome Fusion

(2012) Maaike S. Pols et al.   TRAFFIC

The Cell Biology of Phagocytosis

(2011) Ronald S. Flannagan et al.   Annual Review of Pathology-Mechanisms of Disease

Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells

(2011) R. Xie et al.   BLOOD

Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms

(2011) D. R. Balce et al.   BLOOD

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

(2011) Salil Garg et al.   IMMUNITY

Phagosomal Degradation Increases TLR Access to Bacterial Ligands and Enhances Macrophage Sensitivity to Bacteria

(2011) A. J. Wolf et al.   JOURNAL OF IMMUNOLOGY

Phagosome dynamics during phagocytosis by neutrophils

(2011) Pontus Nordenfelt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Rab GTPases Regulating Phagosome Maturation Are Differentially Recruited to Mycobacterial Phagosomes

(2011) Shintaro Seto et al.   TRAFFIC

SNX-BAR-Mediated Endosome Tubulation is Co-ordinated with Endosome Maturation

(2011) Jan R.T. van Weering et al.   TRAFFIC

Identification of the Switch in Early-to-Late Endosome Transition

(2010) Dmitry Poteryaev et al.   CELL

The Mon1-Ccz1 Complex Is the GEF of the Late Endosomal Rab7 Homolog Ypt7

(2010) Mirjana Nordmann et al.   CURRENT BIOLOGY

Receptor mobility, the cytoskeleton, and particle binding during phagocytosis

(2010) Valentin Jaumouillé et al.   CURRENT OPINION IN CELL BIOLOGY

Initial receptor–ligand interactions modulate gene expression and phagosomal properties during both early and late stages of phagocytosis

(2010) Eik Hoffmann et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Defined particle ligands trigger specific defense mechanisms of macrophages

(2010) Tobias Dykstra et al.   Innate Immunity

Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling

(2010) Nan Lu et al.   MOLECULAR BIOLOGY OF THE CELL

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells

(2010) Jason M. Kinchen et al.   NATURE

Cell-free fusion of bacteria-containing phagosomes with endocytic compartments

(2010) U. Becken et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retromer Is Required for Apoptotic Cell Clearance by Phagocytic Receptor Recycling

(2010) D. Chen et al.   SCIENCE

Changing phosphoinositides “on the fly”: how trafficking vesicles avoid an identity crisis

(2009) Roberto J. Botelho   BIOESSAYS

The Phagosomal Proteome in Interferon-γ-Activated Macrophages

(2009) Matthias Trost et al.   IMMUNITY

Direct recruitment of H+-ATPase from lysosomes for phagosomal acidification

(2009) G.-H. Sun-Wada et al.   JOURNAL OF CELL SCIENCE

Transient assembly of F-actin by phagosomes delays phagosome fusion with lysosomes in cargo-overloaded macrophages

(2009) D. Liebl et al.   JOURNAL OF CELL SCIENCE

STIM1 is essential for Fc  receptor activation and autoimmune inflammation

(2008) A. Braun et al.   BLOOD

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P2 in yeast and mouse

(2008) Natsuko Jin et al.   EMBO JOURNAL

Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome

(2008) W.K. Eddie Ip et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Imaging of Rab5 activity identifies essential regulators for phagosome maturation

(2008) Masahiro Kitano et al.   NATURE

Phagosome maturation: going through the acid test

(2008) Jason M. Kinchen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY