Phagosome maturation in polarized macrophages

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

(2013) Nadine Jetten et al.   ANGIOGENESIS

The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H+-ATPase (V-ATPase) and Cytohesin-2

(2013) Hiroyuki Hosokawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteases: Essential Actors in Processing Antigens and Intracellular Toll-Like Receptors

(2013) Bénédicte Manoury   Frontiers in Immunology

12/15-Lipoxygenase Orchestrates the Clearance of Apoptotic Cells and Maintains Immunologic Tolerance

(2012) Stefan Uderhardt et al.   IMMUNITY

Human phagosome processing of Mycobacterium tuberculosisantigens is modulated by interferon-γ and interleukin-10

(2012) Karen Bobadilla et al.   IMMUNOLOGY

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Defining GM-CSF- and Macrophage-CSF-Dependent Macrophage Responses by In Vitro Models

(2012) D. C. Lacey et al.   JOURNAL OF IMMUNOLOGY

Macrophages and Systemic Iron Homeostasis

(2012) Tomas Ganz   Journal of Innate Immunity

Effects of IFN-γ on intracellular trafficking and activity of macrophage NADPH oxidase flavocytochrome b558

(2012) Amy-Jo Casbon et al.   JOURNAL OF LEUKOCYTE BIOLOGY

High-Resolution Transcriptome of Human Macrophages

(2012) Marc Beyer et al.   PLoS One

Asparagine Endopeptidase Controls Anti-Influenza Virus Immune Responses through TLR7 Activation

(2012) Sophia Maschalidi et al.   PLoS Pathogens

Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms

(2011) D. R. Balce et al.   BLOOD

Decoupling of Activation and Effector Binding Underlies ARF6 Priming of Fast Endocytic Recycling

(2011) Guillaume Montagnac et al.   CURRENT BIOLOGY

Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent manner

(2011) Joanna M Rybicka et al.   EMBO JOURNAL

The Solute Carrier Family 15A4 Regulates TLR9 and NOD1 Functions in the Innate Immune System and Promotes Colitis in Mice

(2011) Shigemi Sasawatari et al.   GASTROENTEROLOGY

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

(2011) Anca Sindrilaru et al.   JOURNAL OF CLINICAL INVESTIGATION

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase

(2011) Sarah E. Ewald et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phagosomal Degradation Increases TLR Access to Bacterial Ligands and Enhances Macrophage Sensitivity to Bacteria

(2011) A. J. Wolf et al.   JOURNAL OF IMMUNOLOGY

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification

(2011) D. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vitamin D Is Required for IFN- -Mediated Antimicrobial Activity of Human Macrophages

(2011) M. Fabri et al.   Science Translational Medicine

Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype

(2011) Gaetano Cairo et al.   TRENDS IN IMMUNOLOGY

Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution

(2010) G. Kovtunovych et al.   BLOOD

Impaired host defence against Mycobacterium avium in mice with chronic granulomatous disease

(2010) M. Fujita et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Polarization dictates iron handling by inflammatory and alternatively activated macrophages

(2010) G. Corna et al.   HAEMATOLOGICA

A cation counterflux supports lysosomal acidification

(2010) Benjamin E. Steinberg et al.   JOURNAL OF CELL BIOLOGY

FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport

(2010) Serhiy Pankiv et al.   JOURNAL OF CELL BIOLOGY

Hijacked phagosomes and leukocyte activation: an intimate relationship

(2010) Abdoulaye Oury Barry et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human Heme Oxygenase-1 Deficiency Presenting With Hemolysis, Nephritis, and Asplenia

(2010) Nita Radhakrishnan et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Mast cell/IL-4 control of Francisella tularensis replication and host cell death is associated with increased ATP production and phagosomal acidification

(2010) A R Rodriguez et al.   Mucosal Immunology

NADPH oxidase activity controls phagosomal proteolysis in macrophages through modulation of the lumenal redox environment of phagosomes

(2010) J. M. Rybicka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of PLCβ2 by Endotoxin Plays a Role in the Adenosine A2A Receptor-Mediated Switch of Macrophages from an Inflammatory to an Angiogenic Phenotype

(2009) Stan Grinberg et al.   AMERICAN JOURNAL OF PATHOLOGY

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40phox and selective defects in neutrophil NADPH oxidase activity

(2009) J. D. Matute et al.   BLOOD

Differential regulation of iron homeostasis during human macrophage polarized activation

(2009) Stefania Recalcati et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Phagosomal Proteome in Interferon-γ-Activated Macrophages

(2009) Matthias Trost et al.   IMMUNITY

The Small GTPase Rac2 Controls Phagosomal Alkalinization and Antigen Crosspresentation Selectively in CD8+ Dendritic Cells

(2009) Ariel Savina et al.   IMMUNITY

Critical Role for Asparagine Endopeptidase in Endocytic Toll-like Receptor Signaling in Dendritic Cells

(2009) Fernando E. Sepulveda et al.   IMMUNITY

pH-dependent Internalization of Muramyl Peptides from Early Endosomes Enables Nod1 and Nod2 Signaling

(2009) Jooeun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Susceptibility to Mycobacterial Infections in Children With X-Linked Chronic Granulomatous Disease

(2009) Pamela P. W. Lee et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Chronic Granulomatous Disease: The European Experience

(2009) J. Merlijn van den Berg et al.   PLoS One

Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo

(2009) S. Soe-Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of antibacterial autophagy by NADPH oxidases

(2009) J. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cathepsins are required for Toll-like receptor 9 responses

(2008) Fumi Matsumoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of phagosomal pH on the size-dependent efficiency of cross-presentation by dendritic cells

(2008) Kenny K. Tran et al.   BIOMATERIALS

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

(2008) A. R. Mantegazza et al.   BLOOD

Mycobacterium tuberculosis Virulence Is Mediated by PtpA Dephosphorylation of Human Vacuolar Protein Sorting 33B

(2008) Horacio Bach et al.   Cell Host & Microbe

The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function

(2008) Vladimir Marshansky et al.   CURRENT OPINION IN CELL BIOLOGY

Disseminated Bacillus Calmette-Guérin lymphadenitis in a patient with gp91phox − chronic granulomatous disease 25 years after vaccination

(2008) Koichi Kusuhara et al.   EUROPEAN JOURNAL OF PEDIATRICS

The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes

(2008) Austin R. Graves et al.   NATURE

Imaging of Rab5 activity identifies essential regulators for phagosome maturation

(2008) Masahiro Kitano et al.   NATURE

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

(2008) Sarah E. Ewald et al.   NATURE

A pathway for phagosome maturation during engulfment of apoptotic cells

(2008) Jason M. Kinchen et al.   NATURE CELL BIOLOGY

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

(2008) Boyoun Park et al.   NATURE IMMUNOLOGY

Phagosome maturation: going through the acid test

(2008) Jason M. Kinchen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Th1–Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages

(2008) James Harris et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY