Application of Induced Pluripotent Stem Cells for Disease Modeling and 3D Model Construction: Focus on Osteoarthritis
出版年份 2021 全文链接
标题
Application of Induced Pluripotent Stem Cells for Disease Modeling and 3D Model Construction: Focus on Osteoarthritis
作者
关键词
-
出版物
Cells
Volume 10, Issue 11, Pages 3032
出版商
MDPI AG
发表日期
2021-11-05
DOI
10.3390/cells10113032
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis
- (2021) Chia-Lung Wu et al. Nature Communications
- Advancements in stem cell-derived hepatocyte-like cell models for hepatotoxicity testing
- (2021) Meixian Jin et al. Stem Cell Research & Therapy
- Recent Updates of Diagnosis, Pathophysiology, and Treatment on Osteoarthritis of the Knee
- (2021) Sunhee Jang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Recent Developments in Clinical Applications of Mesenchymal Stem Cells in the Treatment of Rheumatoid Arthritis and Osteoarthritis
- (2021) Joel Jihwan Hwang et al. Frontiers in Immunology
- Characterization of Early-Onset Finger Osteoarthritis-Like Condition Using Patient-Derived Induced Pluripotent Stem Cells
- (2021) Yeri Alice Rim et al. Cells
- NIH reverses Trump-era restrictions on fetal-tissue research
- (2021) Nidhi Subbaraman NATURE
- Generation of a human iPSC line CIBi009-A from a patient with familial hypercholesterolemia carrying variants of LDLR c.T1241G and APOB c.G1618T
- (2021) Wenkun Ge et al. Stem Cell Research
- Cardiac organoid — a promising perspective of preclinical model
- (2021) Dandan Zhao et al. Stem Cell Research & Therapy
- Patterned, organoid-based cartilaginous implants exhibit zone specific functionality forming osteochondral-like tissues in vivo
- (2021) Gabriella Nilsson Hall et al. BIOMATERIALS
- Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
- (2021) Cindy G. Boer et al. CELL
- Organ-on-a-chip: recent breakthroughs and future prospects
- (2020) Qirui Wu et al. Biomedical Engineering Online
- Addressing variability in iPSC-derived models of human disease: guidelines to promote reproducibility
- (2020) Viola Volpato et al. Disease Models & Mechanisms
- In Vitro Fabrication of Hybrid Bone/Cartilage Complex Using Mouse Induced Pluripotent Stem Cells
- (2020) Phoonsuk Limraksasin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Generation and characterization of human induced pluripotent stem cells (iPSCs) from hand osteoarthritis patient-derived fibroblasts
- (2020) R. Castro-Viñuelas et al. Scientific Reports
- Chondrogenic Differentiation from Induced Pluripotent Stem Cells Using Non-Viral Minicircle Vectors
- (2020) Yeri Alice Rim et al. Cells
- Multi-lineage Human iPSC-Derived Platforms for Disease Modeling and Drug Discovery
- (2020) Arun Sharma et al. Cell Stem Cell
- The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression
- (2020) Yeri Alice Rim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Modeling Cardiovascular Diseases with hiPSC-Derived Cardiomyocytes in 2D and 3D Cultures
- (2020) Claudia Sacchetto et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Modeling and Targeting Alzheimer’s Disease With Organoids
- (2020) Angelos Papaspyropoulos et al. Frontiers in Pharmacology
- Human Induced Pluripotent Stem Cell-Derived 3D-Neurospheres Are Suitable for Neurotoxicity Screening
- (2020) Julianna Kobolak et al. Cells
- Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity
- (2020) Dylan J. Richards et al. Nature Biomedical Engineering
- Modeling Cardiac Disease Mechanisms Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Progress, Promises and Challenges
- (2020) Elvira Immacolata Parrotta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Prevention of tumor risk associated with the reprogramming of human pluripotent stem cells
- (2020) Kenly Wuputra et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Human organoids: model systems for human biology and medicine
- (2020) Jihoon Kim et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- 3D culture of functional human iPSC-derived hepatocytes using a core-shell microfiber
- (2020) Shogo Nagata et al. PLoS One
- A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1
- (2020) Mercedes A. Hernández-Sapiéns et al. Frontiers in Cellular Neuroscience
- Aligned nanofiber scaffolds improve functionality of cardiomyocytes differentiated from human induced pluripotent stem cell-derived cardiac progenitor cells
- (2020) Mei Ding et al. Scientific Reports
- Screening for modulators of neural network activity in 3D human iPSC-derived cortical spheroids
- (2020) Grace Woodruff et al. PLoS One
- Regulatory considerations for developing a phase I investigational new drug application for autologous induced pluripotent stem cells ‐based therapy product
- (2020) Balendu Shekhar Jha et al. Stem Cells Translational Medicine
- Utility of direct 3D co-culture model for chondrogenic differentiation of mesenchymal stem cells on hyaluronan scaffold (Hyaff-11)
- (2020) Iwona Deszcz et al. Regenerative Biomaterials
- Formation of Osteochondral Organoids from Murine Induced Pluripotent Stem Cells
- (2020) Shannon K. O'Connor et al. TISSUE ENGINEERING PART A
- The Role of Fibrosis in Osteoarthritis Progression
- (2020) Yeri Alice Rim et al. Life-Basel
- Transcriptional response of human articular chondrocytes treated with fibronectin fragments: an in vitro model of the osteoarthritis phenotype
- (2020) K.S.M. Reed et al. OSTEOARTHRITIS AND CARTILAGE
- Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data
- (2019) Ioanna Tachmazidou et al. NATURE GENETICS
- The potential and limitations of induced pluripotent stem cells to achieve wound healing
- (2019) Jolanta Gorecka et al. Stem Cell Research & Therapy
- Induced Pluripotent Stem Cell–Derived Cardiomyocytes from a Patient with MYL2-R58Q-Mediated Apical Hypertrophic Cardiomyopathy Show Hypertrophy, Myofibrillar Disarray, and Calcium Perturbations
- (2019) Wei Zhou et al. Journal of Cardiovascular Translational Research
- Assessment of iPSC teratogenicity throughout directed differentiation toward an alveolar-like phenotype
- (2019) Adam Mitchell et al. DIFFERENTIATION
- 3D Primary Hepatocyte Culture Systems for Analyses of Liver Diseases, Drug Metabolism, and Toxicity: Emerging Culture Paradigms and Applications
- (2019) Volker M. Lauschke et al. Biotechnology Journal
- iPSC s: A powerful tool for skeletal muscle tissue engineering
- (2019) María Ortuño‐Costela et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Modeling Reentry in the Short QT Syndrome With Human-Induced Pluripotent Stem Cell–Derived Cardiac Cell Sheets
- (2019) Rami Shinnawi et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Current Challenges of iPSC-Based Disease Modeling and Therapeutic Implications
- (2019) Michael Xavier Doss et al. Cells
- Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
- (2019) Rie Ouchi et al. Cell Metabolism
- Modeling Hypertrophic Cardiomyopathy: Mechanistic Insights and Pharmacological Intervention
- (2019) Diogo Mosqueira et al. TRENDS IN MOLECULAR MEDICINE
- Low-density lipoprotein receptor-deficient hepatocytes differentiated from induced pluripotent stem cells allow familial hypercholesterolemia modeling, CRISPR/Cas-mediated genetic correction, and productive hepatitis C virus infection
- (2019) Jérôme Caron et al. Stem Cell Research & Therapy
- Modeling Alzheimer’s disease with iPSC-derived brain cells
- (2019) Jay Penney et al. MOLECULAR PSYCHIATRY
- Research and therapy with induced pluripotent stem cells (iPSCs): social, legal, and ethical considerations
- (2019) Sharif Moradi et al. Stem Cell Research & Therapy
- Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling
- (2019) Soheil Akbari et al. Stem Cell Reports
- iPSCs-Based Neural 3D Systems: A Multidimensional Approach for Disease Modeling and Drug Discovery
- (2019) Gianluca Costamagna et al. Cells
- Osteochondral Tissue Chip Derived From iPSCs: Modeling OA Pathologies and Testing Drugs
- (2019) Zixuan Lin et al. Frontiers in Bioengineering and Biotechnology
- Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer
- (2018) Zhen Liu et al. CELL
- Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond
- (2018) Chun Liu et al. DEVELOPMENT
- Repair potential of nonsurgically delivered induced pluripotent stem cell-derived chondrocytes in a rat osteochondral defect model
- (2018) Yeri Alice Rim et al. Journal of Tissue Engineering and Regenerative Medicine
- 2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling
- (2018) Eduarda G Z Centeno et al. Molecular Neurodegeneration
- Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector
- (2018) Chengzhong Wang et al. NATURE MEDICINE
- Development of In Vitro Drug-Induced Cardiotoxicity Assay by Using Three-Dimensional Cardiac Tissues Derived from Human Induced Pluripotent Stem Cells
- (2018) Maki Takeda et al. TISSUE ENGINEERING PART C-METHODS
- Different Chondrogenic Potential among Human Induced Pluripotent Stem Cells from Diverse Origin Primary Cells
- (2018) Yeri Alice Rim et al. Stem Cells International
- Stem Cells for Cartilage Regeneration: A Roadmap to the Clinic
- (2018) Celeste Scotti et al. Stem Cells International
- Phosphorylation of different tau sites during progression of Alzheimer’s disease
- (2018) Joerg Neddens et al. Acta Neuropathologica Communications
- Liver diseases in the dish: iPSC and organoids as a new approach to modeling liver diseases
- (2018) Romina Fiorotto et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Characterization and Validation of a Human 3D Cardiac Microtissue for the Assessment of Changes in Cardiac Pathology
- (2018) Caroline R. Archer et al. Scientific Reports
- Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development
- (2018) Peter Karagiannis et al. PHYSIOLOGICAL REVIEWS
- Recapitulation of methotrexate hepatotoxicity with induced pluripotent stem cell-derived hepatocytes from patients with rheumatoid arthritis
- (2018) Juryun Kim et al. Stem Cell Research & Therapy
- Modeling Disease with Human Inducible Pluripotent Stem Cells
- (2018) Rodrigo Grandy et al. Annual Review of Pathology-Mechanisms of Disease
- The potential of induced pluripotent stem cells as a tool to study skeletal dysplasias and cartilage-related pathologic conditions
- (2017) H. Liu et al. OSTEOARTHRITIS AND CARTILAGE
- Disease Modeling in Stem Cell-Derived 3D Organoid Systems
- (2017) Devanjali Dutta et al. TRENDS IN MOLECULAR MEDICINE
- Cord blood cell-derived iPSCs as a new candidate for chondrogenic differentiation and cartilage regeneration
- (2017) Yoojun Nam et al. Stem Cell Research & Therapy
- Osteoarthritis: toward a comprehensive understanding of pathological mechanism
- (2017) Di Chen et al. Bone Research
- Chondrogenic Pellet Formation from Cord Blood-derived Induced Pluripotent Stem Cells
- (2017) Yoojun Nam et al. Jove-Journal of Visualized Experiments
- Characteristics and risk factors of rheumatoid arthritis in the United States: an NHANES analysis
- (2017) Bei Xu et al. PeerJ
- The Immunogenicity and Immune Tolerance of Pluripotent Stem Cell Derivatives
- (2017) Xin Liu et al. Frontiers in Immunology
- Cartilage Tissue Engineering by the 3D Bioprinting of iPS Cells in a Nanocellulose/Alginate Bioink
- (2017) Duong Nguyen et al. Scientific Reports
- Human Validation of Genes Associated With a Murine Atherosclerotic PhenotypeHighlights
- (2016) Gerard Pasterkamp et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Disease modelling using human iPSCs
- (2016) Stormy J. Chamberlain HUMAN MOLECULAR GENETICS
- Three dimensional collagen scaffolds promote iPSC induction with higher pluripotency
- (2016) Qi Gu et al. Protein & Cell
- Chondrocytes Derived From Mesenchymal Stromal Cells and Induced Pluripotent Cells of Patients With Familial Osteochondritis Dissecans Exhibit an Endoplasmic Reticulum Stress Response and Defective Matrix Assembly
- (2016) Maojia Xu et al. Stem Cells Translational Medicine
- Preventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders
- (2016) Aurelie Bedel et al. Stem Cells Translational Medicine
- The Generation of Human Induced Pluripotent Stem Cells from Blood Cells: An Efficient Protocol Using Serial Plating of Reprogrammed Cells by Centrifugation
- (2016) Youngkyun Kim et al. Stem Cells International
- Association Between Overweight and Obesity and Risk of Clinically Diagnosed Knee, Hip, and Hand Osteoarthritis: A Population-Based Cohort Study
- (2016) Carlen Reyes et al. Arthritis & Rheumatology
- Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes
- (2016) Waseem K. Raja et al. PLoS One
- Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression
- (2015) Giuseppe Musumeci et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Diabetes is a risk factor for knee osteoarthritis progression
- (2015) F. Eymard et al. OSTEOARTHRITIS AND CARTILAGE
- Animal Models of Osteoarthritis
- (2015) A. M. McCoy VETERINARY PATHOLOGY
- Generation of Scaffoldless Hyaline Cartilaginous Tissue from Human iPSCs
- (2015) Akihiro Yamashita et al. Stem Cell Reports
- The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis
- (2014) Piotr Wojdasiewicz et al. MEDIATORS OF INFLAMMATION
- Statin treatment rescues FGFR3 skeletal dysplasia phenotypes
- (2014) Akihiro Yamashita et al. NATURE
- Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
- (2014) Gang Wang et al. NATURE MEDICINE
- Current and future impact of osteoarthritis on health care: a population-based study with projections to year 2032
- (2014) A. Turkiewicz et al. OSTEOARTHRITIS AND CARTILAGE
- Genes Involved in the Osteoarthritis Process Identified through Genome Wide Expression Analysis in Articular Cartilage; the RAAK Study
- (2014) Yolande F. M. Ramos et al. PLoS One
- Patient-Derived Skeletal Dysplasia Induced Pluripotent Stem Cells Display Abnormal Chondrogenic Marker Expression and Regulation by BMP2 and TGFβ1
- (2014) Biagio Saitta et al. STEM CELLS AND DEVELOPMENT
- Functional Comparison of Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Cells and Bone Marrow-Derived Mesenchymal Stromal Cells from the Same Donor
- (2014) Solvig Diederichs et al. STEM CELLS AND DEVELOPMENT
- Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis
- (2014) Jaecheol Lee et al. ARTHRITIS RESEARCH & THERAPY
- Use of Cartilage Derived From Murine Induced Pluripotent Stem Cells for Osteoarthritis Drug Screening
- (2014) Vincent P. Willard et al. Arthritis & Rheumatology
- Animal Models of Osteoarthritis: Challenges of Model Selection and Analysis
- (2013) Erin Teeple et al. AAPS Journal
- Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer
- (2013) Masahito Tachibana et al. CELL
- Cytosystems dynamics in self-organization of tissue architecture
- (2013) Yoshiki Sasai NATURE
- Vascularized and functional human liver from an iPSC-derived organ bud transplant
- (2013) Takanori Takebe et al. NATURE
- Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies
- (2013) Andrew S Lee et al. NATURE MEDICINE
- Inhibition of pluripotent stem cell-derived teratoma formation by small molecules
- (2013) M.-O. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation
- (2013) Y. Lei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells
- (2013) Uri Ben-David et al. Nature Communications
- JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia
- (2012) Max A. Cayo et al. HEPATOLOGY
- Induced Pluripotent Stem Cells as a Disease Modeling and Drug Screening Platform
- (2012) Antje D. Ebert et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
- (2012) Mason A. Israel et al. NATURE
- Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells
- (2012) B. O. Diekman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mapping pathogenesis of arthritis through small animal models
- (2012) T. L. Vincent et al. RHEUMATOLOGY
- Generation of human induced pluripotent stem cells from osteoarthritis patient-derived synovial cells
- (2011) Min-Jeong Kim et al. ARTHRITIS AND RHEUMATISM
- Design properties of hydrogel tissue-engineering scaffolds
- (2011) Junmin Zhu et al. Expert Review of Medical Devices
- Genetics and epigenetics of osteoarthritis
- (2011) Louise N. Reynard et al. MATURITAS
- An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells
- (2011) Chad Tang et al. NATURE BIOTECHNOLOGY
- Harnessing the potential of induced pluripotent stem cells for regenerative medicine
- (2011) Sean M. Wu et al. NATURE CELL BIOLOGY
- A more efficient method to generate integration-free human iPS cells
- (2011) Keisuke Okita et al. NATURE METHODS
- Induced pluripotent stem cells — opportunities for disease modelling and drug discovery
- (2011) Marica Grskovic et al. NATURE REVIEWS DRUG DISCOVERY
- Intramyocardial Transplantation of Undifferentiated Rat Induced Pluripotent Stem Cells Causes Tumorigenesis in the Heart
- (2011) Yuzhen Zhang et al. PLoS One
- A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects
- (2010) Jinqiu Zhang et al. Cell Stem Cell
- Induction of Mesenchymal Progenitor Cells with Chondrogenic Property from Mouse-Induced Pluripotent Stem Cells
- (2010) Takeshi Teramura et al. Cellular Reprogramming
- Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis
- (2010) Diane van der Woude et al. NATURE GENETICS
- Reconstituting Organ-Level Lung Functions on a Chip
- (2010) D. Huh et al. SCIENCE
- Human Induced Pluripotent Stem Cells Develop Teratoma More Efficiently and Faster Than Human Embryonic Stem Cells Regardless the Site of Injection
- (2010) Ivan Gutierrez-Aranda et al. STEM CELLS
- Human Induced Pluripotent Stem Cells Derived from Fetal Neural Stem Cells Successfully Undergo Directed Differentiation into Cartilage
- (2010) Sergey P. Medvedev et al. STEM CELLS AND DEVELOPMENT
- Ethical Issues in Stem Cell Research
- (2009) Bernard Lo et al. ENDOCRINE REVIEWS
- Disease-Specific Induced Pluripotent Stem Cells
- (2008) In-Hyun Park et al. CELL
- c-Myc Is Dispensable for Direct Reprogramming of Mouse Fibroblasts
- (2008) Marius Wernig et al. Cell Stem Cell
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