Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development
出版年份 2018 全文链接
标题
Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development
作者
关键词
-
出版物
PHYSIOLOGICAL REVIEWS
Volume 99, Issue 1, Pages 79-114
出版商
American Physiological Society
发表日期
2018-10-17
DOI
10.1152/physrev.00039.2017
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Stem Cells in Pulmonary Disease and Regeneration
- (2018) Rohan R. Nadkarni et al. CHEST
- Allele-specific ablation rescues electrophysiological abnormalities in a human iPS cell model of long-QT syndrome with a CALM2 mutation
- (2017) Yuta Yamamoto et al. HUMAN MOLECULAR GENETICS
- Making human cardiomyocytes up to date: Derivation, maturation state and perspectives
- (2017) Tomasz J. Kolanowski et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva
- (2017) Kyosuke Hino et al. JOURNAL OF CLINICAL INVESTIGATION
- Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells
- (2017) Jiho Choi et al. NATURE
- Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model
- (2017) Tetsuhiro Kikuchi et al. NATURE
- Common genetic variation drives molecular heterogeneity in human iPSCs
- (2017) Helena Kilpinen et al. NATURE
- Interspecies organogenesis generates autologous functional islets
- (2017) Tomoyuki Yamaguchi et al. NATURE
- Regenerative medicine and cell-based approaches to restore pancreatic function
- (2017) Cara Ellis et al. Nature Reviews Gastroenterology & Hepatology
- Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration
- (2017) Michiko Mandai et al. NEW ENGLAND JOURNAL OF MEDICINE
- Public attitudes in Japan towards human–animal chimeric embryo research using human induced pluripotent stem cells
- (2017) Tsutomu Sawai et al. Regenerative Medicine
- CSAHi study-2: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes: Assessment of reference compounds and comparison with non-clinical studies and clinical information
- (2017) Yumiko Nozaki et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis
- (2017) Keiko Imamura et al. Science Translational Medicine
- Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions
- (2017) Elias Uhlin et al. Stem Cell Research
- Generation of non-transgenic iPS cells from human cord blood CD34 + cells under animal component-free conditions
- (2017) Alexandra Haase et al. Stem Cell Research
- Simple and effective generation of transgene-free induced pluripotent stem cells using an auto-erasable Sendai virus vector responding to microRNA-302
- (2017) Ken Nishimura et al. Stem Cell Research
- Concise Review: Criteria for Chamber-Specific Categorization of Human Cardiac Myocytes Derived from Pluripotent Stem Cells
- (2017) Christopher Kane et al. STEM CELLS
- Modelling Torsade de Pointes arrhythmias in vitro in 3D human iPS cell-engineered heart tissue
- (2017) Masahide Kawatou et al. Nature Communications
- MHC matching improves engraftment of iPSC-derived neurons in non-human primates
- (2017) Asuka Morizane et al. Nature Communications
- Current strategies to generate mature human induced pluripotent stem cells derived cholangiocytes and future applications
- (2017) Eduardo Cervantes-Alvarez et al. Organogenesis
- iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer’s Disease
- (2017) Takayuki Kondo et al. Cell Reports
- Cardiac voltage-gated ion channels in safety pharmacology: Review of the landscape leading to the CiPA initiative
- (2017) Hai Huang et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes
- (2017) Hiroyuki Ando et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Tips from the embryonic lung
- (2017) Avinash Waghray et al. eLife
- Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells
- (2017) Francesca Stillitano et al. eLife
- Skeletal Muscle Cell Induction from Pluripotent Stem Cells
- (2017) Yusaku Kodaka et al. Stem Cells International
- Inhibition of CDK5 Alleviates the Cardiac Phenotypes in Timothy Syndrome
- (2017) LouJin Song et al. Stem Cell Reports
- An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells
- (2017) Yuta Koui et al. Stem Cell Reports
- New Models for Therapeutic Innovation from Japan
- (2017) Peter Karagiannis et al. EBioMedicine
- iPS cell technologies and their prospect for bone regeneration and disease modeling: A mini review
- (2017) Maria Csobonyeiova et al. Journal of Advanced Research
- Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause
- (2016) Roberta Scognamiglio et al. CELL
- Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity
- (2016) Masatoshi Nishizawa et al. Cell Stem Cell
- Age-Related Accumulation of Somatic Mitochondrial DNA Mutations in Adult-Derived Human iPSCs
- (2016) Eunju Kang et al. Cell Stem Cell
- Gametogenesis from Pluripotent Stem Cells
- (2016) Mitinori Saitou et al. Cell Stem Cell
- A Precision Medicine Approach to the Rescue of Function on Malignant Calmodulinopathic Long-QT SyndromeNovelty and Significance
- (2016) Worawan B. Limpitikul et al. CIRCULATION RESEARCH
- Human derived cardiomyocytes: A decade of knowledge after the discovery of induced pluripotent stem cells
- (2016) Andrea Barbuti et al. DEVELOPMENTAL DYNAMICS
- Natural underlying mtDNA heteroplasmy as a potential source of intra‐person hiPSC variability
- (2016) Ester Perales‐Clemente et al. EMBO JOURNAL
- Induction of steroidogenic cells from adult stem cells and pluripotent stem cells [Review]
- (2016) Takashi Yazawa et al. ENDOCRINE JOURNAL
- Hepatocyte-like cells derived from induced pluripotent stem cells
- (2016) Namita Roy-Chowdhury et al. Hepatology International
- Efficient genomic correction methods in human iPS cells using CRISPR–Cas9 system
- (2016) Hongmei Lisa Li et al. METHODS
- Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions
- (2016) Ann-Kathrin Börger et al. MOLECULAR MEDICINE
- Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts
- (2016) Yuji Shiba et al. NATURE
- Progress towards generation of human haematopoietic stem cells
- (2016) Lara Wahlster et al. NATURE CELL BIOLOGY
- Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity
- (2016) Paul W Burridge et al. NATURE MEDICINE
- Generating and regenerating the digestive system
- (2016) James M. Wells Nature Reviews Gastroenterology & Hepatology
- Pluripotent stem cells in disease modelling and drug discovery
- (2016) Yishai Avior et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Pluripotent stem cells progressing to the clinic
- (2016) Alan Trounson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Understanding kidney morphogenesis to guide renal tissue regeneration
- (2016) Melissa H. Little et al. Nature Reviews Nephrology
- Cell Therapy for Parkinson’s Disease
- (2016) Asuka MORIZANE et al. NEUROLOGIA MEDICO-CHIRURGICA
- Induction of nephron progenitors and glomeruli from human pluripotent stem cells
- (2016) Ryuichi Nishinakamura et al. PEDIATRIC NEPHROLOGY
- Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential
- (2016) Wataru Yamamoto et al. PLoS One
- CSAHi study: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes -assessment of inter-facility and cells lot-to-lot-variability-
- (2016) Yumiko Nozaki et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Generation of human iPS cell line CTL07-II from human fibroblasts, under defined and xeno-free conditions
- (2016) Malin Kele et al. Stem Cell Research
- From Early Embryonic to Adult Stage: Comparative Study of Action Potentials of Native and Pluripotent Stem Cell-Derived Cardiomyocytes
- (2016) Gabriel Peinkofer et al. STEM CELLS AND DEVELOPMENT
- Malfunction in Mitochondrial β-Oxidation Contributes to Lipid Accumulation in Hepatocyte-Like Cells Derived from Citrin Deficiency-Induced Pluripotent Stem Cells
- (2016) Yeji Kim et al. STEM CELLS AND DEVELOPMENT
- Comprehensive Translational Assessment of Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias
- (2016) Ksenia Blinova et al. TOXICOLOGICAL SCIENCES
- Rewinding the process of mammalian extinction
- (2016) Joseph Saragusty et al. ZOO BIOLOGY
- Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors
- (2016) Wei Wen et al. Stem Cell Reports
- Recent policies that support clinical application of induced pluripotent stem cell-based regenerative therapies
- (2016) Kentaro Azuma et al. Regenerative Therapy
- Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice
- (2016) Sota Kodama et al. Scientific Reports
- Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons
- (2016) Keiko Imamura et al. Scientific Reports
- Alzheimer's in 3D culture: Challenges and perspectives
- (2015) Carla D'Avanzo et al. BIOESSAYS
- Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer’s disease donor as a model for investigating AD-associated gene regulatory networks
- (2015) Amir M Hossini et al. BMC GENOMICS
- iPS cell technologies and cartilage regeneration
- (2015) Noriyuki Tsumaki et al. BONE
- Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency
- (2015) Davide Cacchiarelli et al. CELL
- FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders
- (2015) Jessica Mariani et al. CELL
- Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches
- (2015) Kenji Miki et al. Cell Stem Cell
- Lymphoid Regeneration from Gene-Corrected SCID-X1 Subject-Derived iPSCs
- (2015) Tushar Menon et al. Cell Stem Cell
- Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells
- (2015) Jessica E. Young et al. Cell Stem Cell
- From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical Trial
- (2015) John McNeish et al. Cell Stem Cell
- Differentiation of pluripotent stem cells into endothelial cells
- (2015) Mervin C. Yoder CURRENT OPINION IN HEMATOLOGY
- How to make an oligodendrocyte
- (2015) S. A. Goldman et al. DEVELOPMENT
- Efficient episomal reprogramming of blood mononuclear cells and differentiation to hepatocytes with functional drug metabolism
- (2015) Jing Liu et al. EXPERIMENTAL CELL RESEARCH
- Efficient Reprogramming of Human Fibroblasts and Blood-Derived Endothelial Progenitor Cells Using Nonmodified RNA for Reprogramming and Immune Evasion
- (2015) Marco Alexander Poleganov et al. HUMAN GENE THERAPY
- Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus
- (2015) Marta Byrska-Bishop et al. JOURNAL OF CLINICAL INVESTIGATION
- Manipulating megakaryocytes to manufacture plateletsex vivo
- (2015) P. Karagiannis et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Current advances in the generation of human iPS cells: implications in cell-based regenerative medicine
- (2015) Ana Revilla et al. Journal of Tissue Engineering and Regenerative Medicine
- Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
- (2015) Minoru Takasato et al. NATURE
- Directed differentiation of cholangiocytes from human pluripotent stem cells
- (2015) Mina Ogawa et al. NATURE BIOTECHNOLOGY
- Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
- (2015) Fotios Sampaziotis et al. NATURE BIOTECHNOLOGY
- A 3D human neural cell culture system for modeling Alzheimer's disease
- (2015) Young Hye Kim et al. Nature Protocols
- Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments
- (2015) Margaret A. Goodell et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Application of human induced pluripotent stem cells for modeling and treating neurodegenerative diseases
- (2015) Natalie L. Payne et al. New Biotechnology
- Neofunction of ACVR1 in fibrodysplasia ossificans progressiva
- (2015) Kyosuke Hino et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency
- (2015) M. J. Ciancanelli et al. SCIENCE
- Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
- (2015) J. T. Hinson et al. SCIENCE
- HPGCD Outperforms HPBCD as a Potential Treatment for Niemann-Pick Disease Type C During Disease Modeling with iPS Cells
- (2015) Minami Soga et al. STEM CELLS
- Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer
- (2015) David L. Hermanson et al. STEM CELLS
- Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells
- (2015) Katrina L. Adams et al. Nature Communications
- APP Metabolism Regulates Tau Proteostasis in Human Cerebral Cortex Neurons
- (2015) Steven Moore et al. Cell Reports
- Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells
- (2015) Keiko Muguruma et al. Cell Reports
- A Facile Method to Establish Human Induced Pluripotent Stem Cells From Adult Blood Cells Under Feeder-Free and Xeno-Free Culture Conditions: A Clinically Compliant Approach
- (2015) Bin-Kuan Chou et al. Stem Cells Translational Medicine
- Pluripotent Cell Models of Fanconi Anemia Identify the Early Pathological Defect in Human Hemoangiogenic Progenitors
- (2015) Naoya M. Suzuki et al. Stem Cells Translational Medicine
- Impaired respiratory function in MELAS-induced pluripotent stem cells with high heteroplasmy levels
- (2015) Masaki Kodaira et al. FEBS Open Bio
- KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency
- (2015) Shin-Il Kim et al. Stem Cell Reports
- Emergence of a Stage-Dependent Human Liver Disease Signature with Directed Differentiation of Alpha-1 Antitrypsin-Deficient iPS Cells
- (2015) Andrew A. Wilson et al. Stem Cell Reports
- Using iPS Cells toward the Understanding of Parkinson’s Disease
- (2015) Roger Torrent et al. Journal of Clinical Medicine
- Molecular pathomechanisms and cell-type-specific disease phenotypes of MELAS caused by mutant mitochondrial tRNATrp
- (2015) Hideyuki Hatakeyama et al. Acta Neuropathologica Communications
- Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells
- (2014) Lu Han et al. CARDIOVASCULAR RESEARCH
- Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human
- (2014) Yasuhiro Takashima et al. CELL
- Expandable Megakaryocyte Cell Lines Enable Clinically Applicable Generation of Platelets from Human Induced Pluripotent Stem Cells
- (2014) Sou Nakamura et al. Cell Stem Cell
- Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency
- (2014) Thorold W. Theunissen et al. Cell Stem Cell
- Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons
- (2014) Hong Chen et al. Cell Stem Cell
- Human Pluripotent Stem Cell Culture: Considerations for Maintenance, Expansion, and Therapeutics
- (2014) Kevin G. Chen et al. Cell Stem Cell
- Molecular genetics of citrullinemia types I and II
- (2014) Hye In Woo et al. CLINICA CHIMICA ACTA
- iPS cells: a game changer for future medicine
- (2014) H. Inoue et al. EMBO JOURNAL
- Mitochondrial DNA disease—molecular insights and potential routes to a cure
- (2014) Oliver Russell et al. EXPERIMENTAL CELL RESEARCH
- The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons
- (2014) Christina R. Muratore et al. HUMAN MOLECULAR GENETICS
- Stem cell derived basal forebrain cholinergic neurons from Alzheimer’s disease patients are more susceptible to cell death
- (2014) Lishu Duan et al. Molecular Neurodegeneration
- Statin treatment rescues FGFR3 skeletal dysplasia phenotypes
- (2014) Akihiro Yamashita et al. NATURE
- A three-dimensional human neural cell culture model of Alzheimer’s disease
- (2014) Se Hoon Choi et al. NATURE
- Pluripotent stem cells in regenerative medicine: challenges and recent progress
- (2014) Viviane Tabar et al. NATURE REVIEWS GENETICS
- Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions
- (2014) Jens Durruthy-Durruthy et al. PLoS One
- Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential
- (2014) M. Ohnuki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells
- (2014) Kaori Isono et al. Stem Cell Research
- Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm
- (2014) Kazutoshi Takahashi et al. Nature Communications
- A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells
- (2014) Masato Nakagawa et al. Scientific Reports
- The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa
- (2014) Tetsu Yoshida et al. Molecular Brain
- Endothelin‐1 Induces Myofibrillar Disarray and Contractile Vector Variability in Hypertrophic Cardiomyopathy–Induced Pluripotent Stem Cell–Derived Cardiomyocytes
- (2014) Atsushi Tanaka et al. Journal of the American Heart Association
- Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells
- (2014) Dorothea Maetzel et al. Stem Cell Reports
- Isolation of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation
- (2014) Daisuke Doi et al. Stem Cell Reports
- Generation of Thyroid Follicular Cells from Pluripotent Stem Cells: Potential for Regenerative Medicine
- (2014) Will Sewell et al. Frontiers in Endocrinology
- Opportunities and Limitations of Modelling Alzheimer’s Disease with Induced Pluripotent Stem Cells
- (2014) Dmitry Ovchinnikov et al. Journal of Clinical Medicine
- A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons
- (2013) Dawei Zhang et al. BIOMATERIALS
- Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia
- (2013) S. Gandre-Babbe et al. BLOOD
- Stability of genomic imprinting in human induced pluripotent stem cells
- (2013) Hitoshi Hiura et al. BMC GENETICS
- Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers
- (2013) Jian Shu et al. CELL
- Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription
- (2013) Scott D. Ryan et al. CELL
- Regeneration of Human Tumor Antigen-Specific T Cells from iPSCs Derived from Mature CD8 + T Cells
- (2013) Raul Vizcardo et al. Cell Stem Cell
- Generation of Rejuvenated Antigen-Specific T Cells by Reprogramming to Pluripotency and Redifferentiation
- (2013) Toshinobu Nishimura et al. Cell Stem Cell
- Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging
- (2013) Justine D. Miller et al. Cell Stem Cell
- Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression
- (2013) Peter Reinhardt et al. Cell Stem Cell
- Toward the Development of a Global Induced Pluripotent Stem Cell Library
- (2013) Marc Turner et al. Cell Stem Cell
- Pluripotent Stem Cell Models of Shwachman-Diamond Syndrome Reveal a Common Mechanism for Pancreatic and Hematopoietic Dysfunction
- (2013) Asmin Tulpule et al. Cell Stem Cell
- Next-Generation Regenerative Medicine: Organogenesis from Stem Cells in 3D Culture
- (2013) Yoshiki Sasai Cell Stem Cell
- Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development
- (2013) Cory R. Nicholas et al. Cell Stem Cell
- Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness
- (2013) Takayuki Kondo et al. Cell Stem Cell
- Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells
- (2013) Feng Lan et al. Cell Stem Cell
- Drug Screening Using a Library of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes Reveals Disease-Specific Patterns of Cardiotoxicity
- (2013) Ping Liang et al. CIRCULATION
- How to make a functional -cell
- (2013) F. W. Pagliuca et al. DEVELOPMENT
- Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes
- (2013) Elena Matsa et al. EUROPEAN HEART JOURNAL
- Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis
- (2013) T. Morishima et al. HAEMATOLOGICA
- Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells
- (2013) Su Mi Choi et al. HEPATOLOGY
- Modeling type 3 long QT syndrome with cardiomyocytes derived from patient-specific induced pluripotent stem cells
- (2013) Dongrui Ma et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells
- (2013) M. W. Amoroso et al. JOURNAL OF NEUROSCIENCE
- High-resolution analysis with novel cell-surface markers identifies routes to iPS cells
- (2013) James O’Malley et al. NATURE
- Vascularized and functional human liver from an iPSC-derived organ bud transplant
- (2013) Takanori Takebe et al. NATURE
- Mechanisms and models of somatic cell reprogramming
- (2013) Yosef Buganim et al. NATURE REVIEWS GENETICS
- Efficient derivation of cortical glutamatergic neurons from human pluripotent stem cells: A model system to study neurotoxicity in Alzheimer's disease
- (2013) Tandis Vazin et al. NEUROBIOLOGY OF DISEASE
- LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction
- (2013) Laurie H. Sanders et al. NEUROBIOLOGY OF DISEASE
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- A Systematic Evaluation of Integration Free Reprogramming Methods for Deriving Clinically Relevant Patient Specific Induced Pluripotent Stem (iPS) Cells
- (2013) Pollyanna A. Goh et al. PLoS One
- Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells
- (2013) T. Hiramoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
- (2013) A. Serio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts
- (2013) K. Tanabe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells
- (2013) M. Koyanagi-Aoi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model
- (2013) R. H. Hamalainen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deficits in human trisomy 21 iPSCs and neurons
- (2013) J. P. Weick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds
- (2013) P. Hou et al. SCIENCE
- Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
- (2013) D. Sareen et al. Science Translational Medicine
- Disease-Causing Mitochondrial Heteroplasmy Segregated Within Induced Pluripotent Stem Cell Clones Derived from a Patient with MELAS
- (2013) Clifford D.L. Folmes et al. STEM CELLS
- Induced Pluripotent Stem Cells with a Mitochondrial DNA Deletion
- (2013) Anne B. C. Cherry et al. STEM CELLS
- Refining the Human iPSC-Cardiomyocyte Arrhythmic Risk Assessment Model
- (2013) Liang Guo et al. TOXICOLOGICAL SCIENCES
- Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes
- (2013) Kimberly R. Doherty et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Safety pharmacology — Current and emerging concepts
- (2013) Junnat Hamdam et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells
- (2013) Grace Woodruff et al. Cell Reports
- Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species
- (2013) Ricardo Antonio Rosselló et al. eLife
- A Panel of CpG Methylation Sites Distinguishes Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
- (2013) Kevin Huang et al. Stem Cell Reports
- Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery
- (2012) T. Tanaka et al. BLOOD
- Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples
- (2012) K. Kumano et al. BLOOD
- Overcoming reprogramming resistance of Fanconi anemia cells
- (2012) L. U. W. Muller et al. BLOOD
- Disease characterization using LQTS-specific induced pluripotent stem cells
- (2012) Toru Egashira et al. CARDIOVASCULAR RESEARCH
- Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome
- (2012) Abdenour Soufi et al. CELL
- A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells
- (2012) Jose M. Polo et al. CELL
- Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase
- (2012) Yosef Buganim et al. CELL
- Genetic correction of β-thalassemia patient-specific iPS cells and its use in improving hemoglobin production in irradiated SCID mice
- (2012) Yixuan Wang et al. CELL RESEARCH
- Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal
- (2012) Jin Zhang et al. Cell Stem Cell
- Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives
- (2012) Kristopher L. Nazor et al. Cell Stem Cell
- Erosion of Dosage Compensation Impacts Human iPSC Disease Modeling
- (2012) Shila Mekhoubad et al. Cell Stem Cell
- Metabolic Plasticity in Stem Cell Homeostasis and Differentiation
- (2012) Clifford D.L. Folmes et al. Cell Stem Cell
- Induced pluripotent stem cells generated from diabetic patients with mitochondrial DNA A3243G mutation
- (2012) J. Fujikura et al. DIABETOLOGIA
- Modeling neurogenesis impairment in down syndrome with induced pluripotent stem cells from Trisomy 21 amniotic fluid cells
- (2012) Huai-En Lu et al. EXPERIMENTAL CELL RESEARCH
- Clinical and Molecular Pathophysiology of Shwachman–Diamond Syndrome
- (2012) Kasiani C. Myers et al. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
- Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics
- (2012) Cecile Terrenoire et al. JOURNAL OF GENERAL PHYSIOLOGY
- Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease
- (2012) Roger A Barker et al. LANCET NEUROLOGY
- Chromatin-modifying enzymes as modulators of reprogramming
- (2012) Tamer T. Onder et al. NATURE
- Progressive degeneration of human neural stem cells caused by pathogenic LRRK2
- (2012) Guang-Hui Liu et al. NATURE
- Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells
- (2012) Fabien G. Lafaille et al. NATURE
- Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
- (2012) Mason A. Israel et al. NATURE
- Programming human pluripotent stem cells into white and brown adipocytes
- (2012) Tim Ahfeldt et al. NATURE CELL BIOLOGY
- Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all–iPS cell mice from terminally differentiated B cells
- (2012) Matthias Stadtfeld et al. NATURE GENETICS
- Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
- (2012) M. Kajiwara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells
- (2012) S. T. Chou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells
- (2012) S. Ruiz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells
- (2012) G. A. MacLean et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy
- (2012) N. Sun et al. Science Translational Medicine
- A Human Stem Cell Model of Early Alzheimer's Disease Pathology in Down Syndrome
- (2012) Y. Shi et al. Science Translational Medicine
- Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells
- (2012) N. Egawa et al. Science Translational Medicine
- Derivation and Functional Analysis of Patient-Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease
- (2012) Yan Jiang et al. STEM CELLS
- An Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells
- (2012) Keisuke Okita et al. STEM CELLS
- Brief Report: Human Pluripotent Stem Cell Models of Fanconi Anemia Deficiency Reveal an Important Role for Fanconi Anemia Proteins in Cellular Reprogramming and Survival of Hematopoietic Progenitors
- (2012) Sun K. Yung et al. STEM CELLS
- Integration-Free Induced Pluripotent Stem Cells Model Genetic and Neural Developmental Features of Down Syndrome Etiology
- (2012) James A. Briggs et al. STEM CELLS
- Alpha-synuclein: from secretion to dysfunction and death
- (2012) O Marques et al. Cell Death & Disease
- Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells
- (2012) Houbo Jiang et al. Nature Communications
- Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells
- (2012) Takamichi Miyazaki et al. Nature Communications
- A 3D microfibrous scaffold for long-term human pluripotent stem cell self-renewal under chemically defined conditions
- (2011) Hong Fang Lu et al. BIOMATERIALS
- Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting
- (2011) J. Zou et al. BLOOD
- Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells
- (2011) K. Hu et al. BLOOD
- Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease
- (2011) J. Zou et al. BLOOD
- Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines
- (2011) Christoph Bock et al. CELL
- Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network
- (2011) Yen-Sin Ang et al. CELL
- Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells
- (2011) Katsuhiko Hayashi et al. CELL
- Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
- (2011) Clifford D.L. Folmes et al. Cell Metabolism
- Generation of hircine-induced pluripotent stem cells by somatic cell reprogramming
- (2011) Jiangtao Ren et al. CELL RESEARCH
- The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming
- (2011) Athanasia D Panopoulos et al. CELL RESEARCH
- Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells
- (2011) Bryce W. Carey et al. Cell Stem Cell
- LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
- (2011) Ha Nam Nguyen et al. Cell Stem Cell
- The Histone Demethylases Jhdm1a/1b Enhance Somatic Cell Reprogramming in a Vitamin-C-Dependent Manner
- (2011) Tao Wang et al. Cell Stem Cell
- Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency
- (2011) Frederick Anokye-Danso et al. Cell Stem Cell
- Reprogramming of Mouse and Human Cells to Pluripotency Using Mature MicroRNAs
- (2011) Norikatsu Miyoshi et al. Cell Stem Cell
- Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
- (2011) A. L. Lahti et al. Disease Models & Mechanisms
- Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia
- (2011) Christian B. Jung et al. EMBO Molecular Medicine
- Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation
- (2011) Elena Matsa et al. EUROPEAN HEART JOURNAL
- Modeling familial Alzheimer's disease with induced pluripotent stem cells
- (2011) Takuya Yagi et al. HUMAN MOLECULAR GENETICS
- Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients
- (2011) Miguel Mitne-Neto et al. HUMAN MOLECULAR GENETICS
- NANOG is a key factor for induction of pluripotency in bovine adult fibroblasts1
- (2011) H. Sumer et al. JOURNAL OF ANIMAL SCIENCE
- Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells
- (2011) P. Seibler et al. JOURNAL OF NEUROSCIENCE
- Generation of Induced Pluripotent Stem Cells from Urine
- (2011) T. Zhou et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
- (2011) Momoko Maekawa et al. NATURE
- Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
- (2011) Kosuke Yusa et al. NATURE
- Modelling schizophrenia using human induced pluripotent stem cells
- (2011) Kristen J. Brennand et al. NATURE
- Self-formation of functional adenohypophysis in three-dimensional culture
- (2011) Hidetaka Suga et al. NATURE
- Somatic coding mutations in human induced pluripotent stem cells
- (2011) Athurva Gore et al. NATURE
- Copy number variation and selection during reprogramming to pluripotency
- (2011) Samer M. Hussein et al. NATURE
- Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
- (2011) Ryan Lister et al. NATURE
- Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
- (2011) Masayuki Yazawa et al. NATURE
- Modelling the long QT syndrome with induced pluripotent stem cells
- (2011) Ilanit Itzhaki et al. NATURE
- Self-organizing optic-cup morphogenesis in three-dimensional culture
- (2011) Mototsugu Eiraku et al. NATURE
- Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells
- (2011) Deepa Subramanyam et al. NATURE BIOTECHNOLOGY
- Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells
- (2011) Kitai Kim et al. NATURE BIOTECHNOLOGY
- Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
- (2011) Amanda M Haidet-Phillips et al. NATURE BIOTECHNOLOGY
- Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
- (2011) Yuki Ohi et al. NATURE CELL BIOLOGY
- Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
- (2011) Sergiu P Paşca et al. NATURE MEDICINE
- Induced pluripotent stem cells from highly endangered species
- (2011) Inbar Friedrich Ben-Nun et al. NATURE METHODS
- Chemically defined conditions for human iPSC derivation and culture
- (2011) Guokai Chen et al. NATURE METHODS
- A more efficient method to generate integration-free human iPS cells
- (2011) Keisuke Okita et al. NATURE METHODS
- Directed differentiation of functional astroglial subtypes from human pluripotent stem cells
- (2011) Robert Krencik et al. Nature Protocols
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts
- (2011) Sandra Varum et al. PLoS One
- Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease
- (2011) Naoki Yahata et al. PLoS One
- SNCA Triplication Parkinson's Patient's iPSC-derived DA Neurons Accumulate α-Synuclein and Are Susceptible to Oxidative Stress
- (2011) Blake Byers et al. PLoS One
- Hippocampal synaptic plasticity in Alzheimer’s disease: what have we learned so far from transgenic models?
- (2011) Cristina Marchetti et al. REVIEWS IN THE NEUROSCIENCES
- Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts
- (2011) Kristina Nagy et al. Stem Cell Reviews and Reports
- The Controlled Generation of Functional Basal Forebrain Cholinergic Neurons from Human Embryonic Stem Cells
- (2011) Christopher J. Bissonnette et al. STEM CELLS
- In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases
- (2011) Vittorio Sebastiano et al. STEM CELLS
- The Role of Human Leukocyte Antigen Matching in the Development of Multiethnic “Haplobank” of Induced Pluripotent Stem Cell Lines
- (2011) Pierre-Antoine Gourraud et al. STEM CELLS
- Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development
- (2011) Richard P. Davis et al. TRENDS IN MOLECULAR MEDICINE
- Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus
- (2011) Michael J. Devine et al. Nature Communications
- DNA Methylation Dynamics in Human Induced Pluripotent Stem Cells over Time
- (2011) Koichiro Nishino et al. PLoS Genetics
- Motor Neuron Diversity in Development and Disease
- (2010) Kevin C. Kanning et al. Annual Review of Neuroscience
- Generation of iPSCs from cultured human malignant cells
- (2010) J. E. Carette et al. BLOOD
- Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells
- (2010) Toshihiro Kobayashi et al. CELL
- A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
- (2010) Maria C.N. Marchetto et al. CELL
- Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds
- (2010) Saiyong Zhu et al. Cell Stem Cell
- Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells
- (2010) Yoav Mayshar et al. Cell Stem Cell
- Generation of Induced Pluripotent Stem Cells from Human Terminally Differentiated Circulating T Cells
- (2010) Tomohisa Seki et al. Cell Stem Cell
- The Nuclear Receptor Nr5a2 Can Replace Oct4 in the Reprogramming of Murine Somatic Cells to Pluripotent Cells
- (2010) Jian-Chien Dominic Heng et al. Cell Stem Cell
- Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
- (2010) Luigi Warren et al. Cell Stem Cell
- A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts
- (2010) Ronghui Li et al. Cell Stem Cell
- Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming
- (2010) Payman Samavarchi-Tehrani et al. Cell Stem Cell
- Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1
- (2010) M. J. Edel et al. GENES & DEVELOPMENT
- Butyrate Promotes Induced Pluripotent Stem Cell Generation
- (2010) Gaoyang Liang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Generation of Human Induced Pluripotent Stem Cells from Umbilical Cord Matrix and Amniotic Membrane Mesenchymal Cells
- (2010) Jinglei Cai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Development of Defective and Persistent Sendai Virus Vector
- (2010) Ken Nishimura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Generation of Induced Pluripotent Stem Cells in Rabbits
- (2010) Arata Honda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells
- (2010) S. Tamir Rashid et al. JOURNAL OF CLINICAL INVESTIGATION
- Transgenic Mouse Models of Alzheimer's Disease
- (2010) Gregory A. Elder et al. MOUNT SINAI JOURNAL OF MEDICINE
- Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
- (2010) Matthias Stadtfeld et al. NATURE
- Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
- (2010) Xonia Carvajal-Vergara et al. NATURE
- Epigenetic memory in induced pluripotent stem cells
- (2010) K. Kim et al. NATURE
- Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
- (2010) Jason R. Spence et al. NATURE
- Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells
- (2010) Eirini P Papapetrou et al. NATURE BIOTECHNOLOGY
- Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511
- (2010) Sergey Rodin et al. NATURE BIOTECHNOLOGY
- Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
- (2010) Jose M Polo et al. NATURE BIOTECHNOLOGY
- Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells
- (2010) Ying Mei et al. NATURE MATERIALS
- A nonviral minicircle vector for deriving human iPS cells
- (2010) Fangjun Jia et al. NATURE METHODS
- Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
- (2010) Jorge J Palop et al. NATURE NEUROSCIENCE
- Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome
- (2010) Alessandra Moretti et al. NEW ENGLAND JOURNAL OF MEDICINE
- Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs
- (2010) Tomomi G. Otsuji et al. Stem Cell Research
- Sox2 expression effects on direct reprogramming efficiency as determined by alternative somatic cell fate
- (2010) Shinpei Yamaguchi et al. Stem Cell Research
- A Cyclic AMP Analog, 8-Br-cAMP, Enhances the Induction of Pluripotency in Human Fibroblast Cells
- (2010) Ying Wang et al. Stem Cell Reviews and Reports
- The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells
- (2010) Alessandro Prigione et al. STEM CELLS
- Generation of induced pluripotent stem cells from human blood
- (2009) Y.-H. Loh et al. BLOOD
- Role of the Murine Reprogramming Factors in the Induction of Pluripotency
- (2009) Rupa Sridharan et al. CELL
- Generation of induced pluripotent stem cells from human β-thalassemia fibroblast cells
- (2009) Yixuan Wang et al. CELL RESEARCH
- iPS Cells Can Support Full-Term Development of Tetraploid Blastocyst-Complemented Embryos
- (2009) Lan Kang et al. Cell Stem Cell
- A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog
- (2009) Justin K. Ichida et al. Cell Stem Cell
- Naive and Primed Pluripotent States
- (2009) Jennifer Nichols et al. Cell Stem Cell
- Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins
- (2009) Dohoon Kim et al. Cell Stem Cell
- Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures
- (2009) Mark H. Chin et al. Cell Stem Cell
- Senescence impairs successful reprogramming to pluripotent stem cells
- (2009) A. Banito et al. GENES & DEVELOPMENT
- Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts
- (2009) Noriko Tsubooka et al. GENES TO CELLS
- Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo
- (2009) Edor Kabashi et al. HUMAN MOLECULAR GENETICS
- Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
- (2009) Hristelina Ilieva et al. JOURNAL OF CELL BIOLOGY
- Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells
- (2009) J. Utikal et al. JOURNAL OF CELL SCIENCE
- Embryonic Stem Cells Proliferate and Differentiate when Seeded into Kidney Scaffolds
- (2009) E. A. Ross et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Elite and stochastic models for induced pluripotent stem cell generation
- (2009) Shinya Yamanaka NATURE
- Adult mice generated from induced pluripotent stem cells
- (2009) Michael J. Boland et al. NATURE
- Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
- (2009) Gabsang Lee et al. NATURE
- Linking the p53 tumour suppressor pathway to somatic cell reprogramming
- (2009) Teruhisa Kawamura et al. NATURE
- Virus-free induction of pluripotency and subsequent excision of reprogramming factors
- (2009) Keisuke Kaji et al. NATURE
- iPS cells produce viable mice through tetraploid complementation
- (2009) Xiao-yang Zhao et al. NATURE
- piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
- (2009) Knut Woltjen et al. NATURE
- A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
- (2009) Rosa M. Marión et al. NATURE
- Suppression of induced pluripotent stem cell generation by the p53–p21 pathway
- (2009) Hyenjong Hong et al. NATURE
- Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
- (2009) Ángel Raya et al. NATURE
- Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
- (2009) Jochen Utikal et al. NATURE
- The Ink4/Arf locus is a barrier for iPS cell reprogramming
- (2009) Han Li et al. NATURE
- Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells
- (2009) Elayne M Chan et al. NATURE BIOTECHNOLOGY
- Variation in the safety of induced pluripotent stem cell lines
- (2009) Kyoko Miura et al. NATURE BIOTECHNOLOGY
- Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
- (2009) Akiko Doi et al. NATURE GENETICS
- Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
- (2009) Noemi FUSAKI et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells
- (2009) N. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation
- (2009) E. P. Papapetrou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Derivation of induced pluripotent stem cells from pig somatic cells
- (2009) T. Ezashi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
- (2009) J. Yu et al. SCIENCE
- Absence of Transverse Tubules Contributes to Non-Uniform Ca2+ Wavefronts in Mouse and Human Embryonic Stem Cell–Derived Cardiomyocytes
- (2009) Deborah K. Lieu et al. STEM CELLS AND DEVELOPMENT
- Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia: molecular classification and treatment options
- (2008) Charlotte Marie Niemeyer et al. BRITISH JOURNAL OF HAEMATOLOGY
- Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency
- (2008) Jacob Hanna et al. CELL
- Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse
- (2008) Matthias Stadtfeld et al. Cell Stem Cell
- Generation of Induced Pluripotent Stem Cells from Adult Rhesus Monkey Fibroblasts
- (2008) Haisong Liu et al. Cell Stem Cell
- Sequential Expression of Pluripotency Markers during Direct Reprogramming of Mouse Somatic Cells
- (2008) Tobias Brambrink et al. Cell Stem Cell
- A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells
- (2008) Nimet Maherali et al. Cell Stem Cell
- Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals
- (2008) Mototsugu Eiraku et al. Cell Stem Cell
- Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds
- (2008) Yan Shi et al. Cell Stem Cell
- Reprogramming of Pancreatic β Cells into Induced Pluripotent Stem Cells
- (2008) Matthias Stadtfeld et al. CURRENT BIOLOGY
- Dissecting direct reprogramming through integrative genomic analysis
- (2008) Tarjei S. Mikkelsen et al. NATURE
- A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
- (2008) Marius Wernig et al. NATURE BIOTECHNOLOGY
- Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
- (2008) Danwei Huangfu et al. NATURE BIOTECHNOLOGY
- Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease
- (2008) K. Haugarvoll et al. NEUROLOGY
- Induced Pluripotent Stem Cells Generated Without Viral Integration
- (2008) M. Stadtfeld et al. SCIENCE
- Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
- (2008) T. Aoi et al. SCIENCE
- Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
- (2008) K. Okita et al. SCIENCE
- Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
- (2008) J. T. Dimos et al. SCIENCE
- Recombinant Vitronectin Is a Functionally Defined Substrate That Supports Human Embryonic Stem Cell Self-Renewal via αVβ5 Integrin
- (2008) Stefan R. Braam et al. STEM CELLS
- Reprogramming of Neural Progenitor Cells into Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 Expression
- (2008) Sarah Eminli et al. STEM CELLS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now