标题
Structure of the human Meckel-Gruber protein Meckelin
作者
关键词
-
出版物
Science Advances
Volume 7, Issue 45, Pages -
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2021-11-04
DOI
10.1126/sciadv.abj9748
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs
- (2021) Lu Xu et al. CELL RESEARCH
- Highly accurate protein structure prediction with AlphaFold
- (2021) John Jumper et al. NATURE
- Limitations and opportunities in the pharmacotherapy of ciliopathies
- (2021) Max Duong Phu et al. PHARMACOLOGY & THERAPEUTICS
- Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling
- (2020) Naotaka Tsutsumi et al. eLife
- Ciliopathies and the Kidney: A Review
- (2020) Dominique J. McConnachie et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- The ciliary Frizzled-like receptor Tmem67 regulates canonical Wnt/β-catenin signalling in the developing cerebellum via Hoxb5
- (2019) Zakia A. Abdelhamed et al. Scientific Reports
- Crystal structure of the Frizzled 4 receptor in a ligand-free state
- (2018) Shifan Yang et al. NATURE
- Structural and Druggability Landscape of Frizzled G Protein-Coupled Receptors
- (2018) Xianjun Zhang et al. TRENDS IN BIOCHEMICAL SCIENCES
- Structural insights into adiponectin receptors suggest ceramidase activity
- (2017) Ieva Vasiliauskaité-Brooks et al. NATURE
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
- (2017) Ali Punjani et al. NATURE METHODS
- Genes and molecular pathways underpinning ciliopathies
- (2017) Jeremy F. Reiter et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- UCSF ChimeraX: Meeting modern challenges in visualization and analysis
- (2017) Thomas D. Goddard et al. PROTEIN SCIENCE
- Meckel–Gruber Syndrome: An Update on Diagnosis, Clinical Management, and Research Advances
- (2017) Verity Hartill et al. Frontiers in Pediatrics
- Gctf: Real-time CTF determination and correction
- (2016) Kai Zhang JOURNAL OF STRUCTURAL BIOLOGY
- Structural basis of Smoothened regulation by its extracellular domains
- (2016) Eamon F. X. Byrne et al. NATURE
- Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
- (2016) Dari Kimanius et al. eLife
- The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway
- (2015) Z. A. Abdelhamed et al. Disease Models & Mechanisms
- Semi-automated selection of cryo-EM particles in RELION-1.3
- (2015) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6
- (2015) Timothy Grant et al. eLife
- Evidence that TMEM67 causes polycystic kidney disease through activation of JNK/ERK-dependent pathways
- (2013) E Du et al. CELL BIOLOGY INTERNATIONAL
- Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel–Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and Wnt signalling defects
- (2013) Zakia A. Abdelhamed et al. HUMAN MOLECULAR GENETICS
- The mechanisms of Hedgehog signalling and its roles in development and disease
- (2013) James Briscoe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
- (2013) Shaoxia Chen et al. ULTRAMICROSCOPY
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways
- (2011) Liyun Sang et al. CELL
- A meckelin–filamin A interaction mediates ciliogenesis
- (2011) Matthew Adams et al. HUMAN MOLECULAR GENETICS
- MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis
- (2011) Corey L. Williams et al. JOURNAL OF CELL BIOLOGY
- COACH Syndrome: An Unusual Cause of Neonatal Cholestasis
- (2011) M. David Weiland et al. JOURNAL OF PEDIATRICS
- A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition
- (2011) Francesc R Garcia-Gonzalo et al. NATURE GENETICS
- Ciliogenesis: building the cell's antenna
- (2011) Hiroaki Ishikawa et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton
- (2009) H. R. Dawe et al. JOURNAL OF CELL SCIENCE
- Mutations in the Cilia Gene ARL13B Lead to the Classical Form of Joubert Syndrome
- (2008) Vincent Cantagrel et al. AMERICAN JOURNAL OF HUMAN GENETICS
- MKS3/TMEM67mutations are a major cause of COACH Syndrome, a Joubert Syndrome related disorder with liver involvement
- (2008) Francesco Brancati et al. HUMAN MUTATION
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started