Structural insights into adiponectin receptors suggest ceramidase activity

Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis

(2017) William L. Holland et al.   Molecular Metabolism

Intramembrane Proteolysis of β-Amyloid Precursor Protein by γ-Secretase Is an Unusually Slow Process

(2015) Frits Kamp et al.   BIOPHYSICAL JOURNAL

A series of ceramide analogs modified at the 1-position with potent activity against the intracellular growth of Chlamydia trachomatis

(2015) Essa M Saied et al.   Future Medicinal Chemistry

CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field

(2015) Jumin Lee et al.   Journal of Chemical Theory and Computation

Crystal structures of the human adiponectin receptors

(2015) Hiroaki Tanabe et al.   NATURE

Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase

(2015) Michael V. Airola et al.   STRUCTURE

Understanding intramembrane proteolysis: from protein dynamics to reaction kinetics

(2015) D. Langosch et al.   TRENDS IN BIOCHEMICAL SCIENCES

CHARMM All-Atom Additive Force Field for Sphingomyelin: Elucidation of Hydrogen Bonding and of Positive Curvature

(2014) Richard M. Venable et al.   BIOPHYSICAL JOURNAL

CHARMM-GUIMembrane Buildertoward realistic biological membrane simulations

(2014) Emilia L. Wu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Decision making inxia2

(2013) Graeme Winter et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography

(2013) James Foadi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

CREST - a large and diverse superfamily of putative transmembrane hydrolases

(2011) Jimin Pei et al.   Biology Direct

SwissDock, a protein-small molecule docking web service based on EADock DSS

(2011) A. Grosdidier et al.   NUCLEIC ACIDS RESEARCH

High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cells

(2011) Allissia A. Gilmartin et al.   PROTEIN ENGINEERING DESIGN & SELECTION

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin

(2010) William L Holland et al.   NATURE MEDICINE

The Disulfide Bonds in Glycoprotein E2 of Hepatitis C Virus Reveal the Tertiary Organization of the Molecule

(2010) Thomas Krey et al.   PLoS Pathogens

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Empirical Scoring Functions for Advanced Protein−Ligand Docking with PLANTS

(2009) Oliver Korb et al.   Journal of Chemical Information and Modeling

Crystallizing membrane proteins using lipidic mesophases

(2009) Martin Caffrey et al.   Nature Protocols

Sphingolipids Function as Downstream Effectors of a Fungal PAQR

(2008) N. Y. Villa et al.   MOLECULAR PHARMACOLOGY

FireDock: a web server for fast interaction refinement in molecular docking

(2008) E. Mashiach et al.   NUCLEIC ACIDS RESEARCH