MLL4 mediates differentiation and tumor suppression through ferroptosis

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The diversity and breadth of cancer cell fatty acid metabolism

(2021) Shilpa R. Nagarajan et al.   Cancer & Metabolism

Emerging Mechanisms and Disease Relevance of Ferroptosis

(2020) Brent R. Stockwell et al.   TRENDS IN CELL BIOLOGY

Extensive heterogeneity in somatic mutation and selection in the human bladder

(2020) Andrew R. J. Lawson et al.   SCIENCE

Macroscopic somatic clonal expansion in morphologically normal human urothelium

(2020) Ruoyan Li et al.   SCIENCE

Selection of oncogenic mutant clones in normal human skin varies with body site

(2020) Joanna C Fowler et al.   Cancer Discovery

Retinoic Acid and Its Derivatives in Skin

(2020) Łukasz Szymański et al.   Cells

COMPASS Ascending: Emerging clues regarding the roles of MLL3/KMT2C and MLL2/KMT2D proteins in cancer

(2019) Richard J. Fagan et al.   CANCER LETTERS

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

(2019) Weimin Wang et al.   NATURE

ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway

(2019) Bo Chu et al.   NATURE CELL BIOLOGY

Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death

(2019) Lia Tesfay et al.   CANCER RESEARCH

Elevated level of mitochondrial reactive oxygen species via fatty acid β-oxidation in cancer stem cells promotes cancer metastasis by inducing epithelial–mesenchymal transition

(2019) Caihua Wang et al.   Stem Cell Research & Therapy

LSD1 Inhibition Promotes Epithelial Differentiation through Derepression of Fate-Determining Transcription Factors

(2019) Shaun Egolf et al.   Cell Reports

KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis

(2018) Enrique Lin-Shiao et al.   GENES & DEVELOPMENT

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

(2018) Joshua D. Campbell et al.   Cell Reports

Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

(2018) Huizhong Feng et al.   PLOS BIOLOGY

Update on Keratinocyte Carcinomas

(2018) Kishwer S. Nehal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers

(2018) R. Kumar et al.   Nature Communications

H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development

(2018) Younghoon Jang et al.   NUCLEIC ACIDS RESEARCH

COSMIC: the Catalogue Of Somatic Mutations In Cancer

(2018) John G Tate et al.   NUCLEIC ACIDS RESEARCH

Human gene essentiality

(2017) István Bartha et al.   NATURE REVIEWS GENETICS

Differential mutation frequencies in metastatic cutaneous squamous cell carcinomas versus primary tumors

(2016) Ayse Selen Yilmaz et al.   CANCER

MLL1 is essential for the senescence-associated secretory phenotype

(2016) Brian C. Capell et al.   GENES & DEVELOPMENT

Targeting metastasis-initiating cells through the fatty acid receptor CD36

(2016) Gloria Pascual et al.   NATURE

The role of barrier genes in epidermal malignancy

(2016) C Darido et al.   ONCOGENE

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Genomic Analysis of Metastatic Cutaneous Squamous Cell Carcinoma

(2015) Y. Y. Li et al.   CLINICAL CANCER RESEARCH

How best to manage patients with chronic lymphocytic leuekmia with 17p deletion and/orTP53mutation?

(2015) Constantine S. Tam et al.   LEUKEMIA & LYMPHOMA

Autophagy mediates degradation of nuclear lamina

(2015) Zhixun Dou et al.   NATURE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

The cancer COMPASS: navigating the functions of MLL complexes in cancer

(2015) David J. Ford et al.   Cancer Genetics

Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma

(2014) C. R. Pickering et al.   CLINICAL CANCER RESEARCH

Role of lipids in the formation and maintenance of the cutaneous permeability barrier

(2013) Kenneth R. Feingold et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The role of lipoxygenases in epidermis

(2013) Peter Krieg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation

(2013) Ji-Eun Lee et al.   eLife

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

(2009) Daniel K. Nomura et al.   CELL

p63 directly induces expression of Alox12, a regulator of epidermal barrier formation

(2009) Soeun Kim et al.   EXPERIMENTAL DERMATOLOGY

Mutation analysis and characterization of COL7A1 mutations in dystrophic epidermolysis bullosa

(2008) Ningning Dang et al.   EXPERIMENTAL DERMATOLOGY

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

(2008) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA