Macroscopic somatic clonal expansion in morphologically normal human urothelium

Tobacco smoking and somatic mutations in human bronchial epithelium

(2020) Kenichi Yoshida et al.   NATURE

The repertoire of mutational signatures in human cancer

(2020) Ludmil B. Alexandrov et al.   NATURE

The mutational landscape of normal human endometrial epithelium

(2020) Luiza Moore et al.   NATURE

Extensive heterogeneity in somatic mutation and selection in the human bladder

(2020) Andrew R. J. Lawson et al.   SCIENCE

Whole-Organ Genomic Characterization of Mucosal Field Effects Initiating Bladder Carcinogenesis

(2019) Tadeusz Majewski et al.   Cell Reports

RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues

(2019) Keren Yizhak et al.   SCIENCE

Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan

(2019) Jesse J. Salk et al.   Cell Reports

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

(2019) Simon F. Brunner et al.   NATURE

The landscape of somatic mutation in normal colorectal epithelial cells

(2019) Henry Lee-Six et al.   NATURE

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

(2018) Katherine A. Hoadley et al.   CELL

Aging and the rise of somatic cancer-associated mutations in normal tissues

(2018) Rosa Ana Risques et al.   PLoS Genetics

Population dynamics of normal human blood inferred from somatic mutations

(2018) Henry Lee-Six et al.   NATURE

Age-related remodelling of oesophageal epithelia by mutated cancer drivers

(2018) Akira Yokoyama et al.   NATURE

Somatic mutant clones colonize the human esophagus with age

(2018) Iñigo Martincorena et al.   SCIENCE

Mutagenic Factors and Complex Clonal Relationship of Multifocal Urothelial Cell Carcinoma

(2017) Yiqing Du et al.   EUROPEAN UROLOGY

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

(2017) Young Seok Ju et al.   NATURE

Aging and neurodegeneration are associated with increased mutations in single human neurons

(2017) Michael A. Lodato et al.   SCIENCE

Different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis

(2017) Taejeong Bae et al.   SCIENCE

Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia

(2017) Alvin W. T. Ng et al.   Science Translational Medicine

Comprehensive multiregional analysis of molecular heterogeneity in bladder cancer

(2017) Mathilde Borg Houlberg Thomsen et al.   Scientific Reports

Somatic mutation in cancer and normal cells

(2015) I. Martincorena et al.   SCIENCE

High burden and pervasive positive selection of somatic mutations in normal human skin

(2015) I. Martincorena et al.   SCIENCE

Mutation signatures implicate aristolochic acid in bladder cancer development

(2015) Song Ling Poon et al.   Genome Medicine

The Split-Apply-Combine Strategy for Data Analysis

(2015) Hadley Wickham   Journal of Statistical Software

Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data

(2014) F. Favero et al.   ANNALS OF ONCOLOGY

Quantification of aristolochic acids I and II in herbal dietary supplements by ultra-high-performance liquid chromatography–multistage fragmentation mass spectrometry

(2014) Lukas Vaclavik et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Naturally occurring aristolochic acid analogues and their toxicities

(2014) Johanna Michl et al.   NATURAL PRODUCT REPORTS

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinoma

(2014) Kunyoo Shin et al.   NATURE CELL BIOLOGY

Chinese Herbs Containing Aristolochic Acid Associated with Renal Failure and Urothelial Carcinoma: A Review from Epidemiologic Observations to Causal Inference

(2014) Hsiao-Yu Yang et al.   Biomed Research International

European Guidelines on Upper Tract Urothelial Carcinomas: 2013 Update

(2013) Morgan Rouprêt et al.   EUROPEAN UROLOGY

EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2013

(2013) Marko Babjuk et al.   EUROPEAN UROLOGY

EAU Guidelines on Muscle-invasive and Metastatic Bladder Cancer: Summary of the 2013 Guidelines

(2013) J. Alfred Witjes et al.   EUROPEAN UROLOGY

Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: Clinical characteristics and outcomes

(2013) Chung-Hsin Chen et al.   INTERNATIONAL JOURNAL OF CANCER

Integrated genomic characterization of endometrial carcinoma

(2013) Gad Getz et al.   NATURE

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation

(2013) Guangwu Guo et al.   NATURE GENETICS

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

(2013) C. Tomasetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Life History of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Clonal evolution in cancer

(2012) Mel Greaves et al.   NATURE

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Absolute quantification of somatic DNA alterations in human cancer

(2012) Scott L Carter et al.   NATURE BIOTECHNOLOGY

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

A human functional protein interaction network and its application to cancer data analysis

(2010) Guanming Wu et al.   GENOME BIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Population-Based Case-Control Study of Chinese Herbal Products Containing Aristolochic Acid and Urinary Tract Cancer Risk

(2009) M.-N. Lai et al.   JNCI-Journal of the National Cancer Institute

The cancer genome

(2009) Michael R. Stratton et al.   NATURE