An Osmotic Laxative Renders Mice Susceptible to Prolonged Clostridioides difficile Colonization and Hinders Clearance

Clostridioides difficile Infection, Still a Long Way to Go

(2021) Eleftheria Kampouri et al.   Journal of Clinical Medicine

Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection

(2021) Pablo Castro-Córdova et al.   Nature Communications

Clostridioides difficile biofilms: A mechanism of persistence in the gut?

(2021) Lucy R. Frost et al.   PLoS Pathogens

Biofilms harbour Clostridioides difficile, serving as a reservoir for recurrent infection

(2021) Charmaine Normington et al.   npj Biofilms and Microbiomes

Dissecting Individual Interactions between Pathogenic and Commensal Bacteria within a Multispecies Gut Microbial Community

(2021) Jack Hassall et al.   mSphere

Reduction in testing and change in testing algorithm associated with decrease in number of nosocomial Clostridioides (Clostridium) difficile infections

(2020) Paul P. Cook et al.   AMERICAN JOURNAL OF INFECTION CONTROL

C. difficile-associated antibiotics alter human mucosal barrier functions by microbiome-independent mechanisms.

(2020) Jemila C. Kester et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Impact of commonly used drugs on the composition and metabolic function of the gut microbiota

(2020) Arnau Vich Vila et al.   Nature Communications

Diarrhoeal events can trigger long-term Clostridium difficile colonization with recurrent blooms

(2020) David VanInsberghe et al.   Nature Microbiology

Characterization of Gut Microbiota in Hospitalized Patients with Clostridioides difficile Infection

(2020) Bahareh Vakili et al.   CURRENT MICROBIOLOGY

Systemic Inflammatory Mediators Are Effective Biomarkers for Predicting Adverse Outcomes in Clostridioides difficile Infection

(2020) Michael G. Dieterle et al.   mBio

A Framework for Effective Application of Machine Learning to Microbiome-Based Classification Problems

(2020) Begüm D. Topçuoğlu et al.   mBio

Intestinal Microbiota in Elderly Inpatients with Clostridioides difficile Infection

(2020) Bahareh Vakili et al.   Infection and Drug Resistance

Fecal Microbiota Transplant is Highly Effective in Real-World Practice: Initial Results from the FMT National Registry

(2020) Colleen R. Kelly et al.   GASTROENTEROLOGY

Proximal colon–derived O-glycosylated mucus encapsulates and modulates the microbiota

(2020) Kirk Bergstrom et al.   SCIENCE

Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization

(2020) Fátima C. Pereira et al.   Nature Communications

The Initial Gut Microbiota and Response to Antibiotic Perturbation Influence Clostridioides difficile Clearance in Mice

(2020) Sarah Tomkovich et al.   mSphere

Fusobacterium nucleatum Adheres to Clostridioides difficile via the RadD Adhesin to Enhance Biofilm Formation in Intestinal Mucus

(2020) Melinda A. Engevik et al.   GASTROENTEROLOGY

Predictors of Clostridioides difficile recurrence across a national cohort of veterans in outpatient, acute, and long-term care settings

(2019) Haley J Appaneal et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Predictors of Clostridioides difficile Infection Among Asymptomatic, Colonized Patients: A Retrospective Cohort Study

(2019) Dominic Poirier et al.   CLINICAL INFECTIOUS DISEASES

Laxative Use Does Not Preclude Diagnosis or Reduce Disease Severity in Clostridiodes difficile Infection

(2019) Nicole C White et al.   CLINICAL INFECTIOUS DISEASES

The Proton Pump Inhibitor Omeprazole Does Not Promote Clostridioides difficile Colonization in a Murine Model

(2019) Sarah Tomkovich et al.   mSphere

Consortium of Probiotics Attenuates Colonization of Clostridioides difficile

(2019) Xianping Li et al.   Frontiers in Microbiology

Transient Osmotic Perturbation Causes Long-Term Alteration to the Gut Microbiota

(2018) Carolina Tropini et al.   CELL

Good Bug, Bad Bug: Breaking through Microbial Stereotypes

(2018) Mihai Cirstea et al.   Cell Host & Microbe

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)

(2018) L Clifford McDonald et al.   CLINICAL INFECTIOUS DISEASES

Evaluation of a best practice alert to reduce unnecessary Clostridium difficile testing following receipt of a laxative

(2018) Anastasia Bilinskaya et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Inhibiting Growth of Clostridioides difficile by Restoring Valerate, Produced by the Intestinal Microbiota

(2018) Julie A.K. McDonald et al.   GASTROENTEROLOGY

A Generalizable, Data-Driven Approach to Predict Daily Risk of Clostridium difficile Infection at Two Large Academic Health Centers

(2018) Jeeheh Oh et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Proton Pump Inhibitors: Review of Emerging Concerns

(2018) Avinash K. Nehra et al.   MAYO CLINIC PROCEEDINGS

Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

(2018) Christine M. Dejea et al.   SCIENCE

Clostridium difficile Alters the Structure and Metabolism of Distinct Cecal Microbiomes during Initial Infection To Promote Sustained Colonization

(2018) Matthew L. Jenior et al.   mSphere

Novel therapies and preventative strategies for primary and recurrent Clostridium difficile infections

(2018) Michael G. Dieterle et al.   Annals of the New York Academy of Sciences

Extensive impact of non-antibiotic drugs on human gut bacteria

(2018) Lisa Maier et al.   NATURE

Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation

(2018) Huimin Deng et al.   Frontiers in Microbiology

Laxative Use in the Setting of Positive Testing for Clostridium difficile Infection

(2017) Syed M. Ahmad et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Faecal microbiota transplantation for Clostridium difficile infection: a multicentre study of non-responders

(2017) Roshan Razik* et al.   MEDICAL JOURNAL OF AUSTRALIA

Clostridium difficile Colonizes Alternative Nutrient Niches during Infection across Distinct Murine Gut Microbiomes

(2017) Matthew L. Jenior et al.   mSystems

Longitudinal survey of Clostridium difficile presence and gut microbiota composition in a Belgian nursing home

(2016) Cristina Rodriguez et al.   BMC MICROBIOLOGY

Persisting changes of intestinal microbiota after bowel lavage and colonoscopy

(2016) Lorenzo Drago et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Bacterial and Fungal Microbiota Changes Distinguish C. difficile Infection from Other Forms of Diarrhea: Results of a Prospective Inpatient Study

(2016) William Sangster et al.   Frontiers in Microbiology

The Effects of Bowel Preparation on Microbiota-Related Metrics Differ in Health and in Inflammatory Bowel Disease and for the Mucosal and Luminal Microbiota Compartments

(2016) Rima M Shobar et al.   Clinical and Translational Gastroenterology

Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates

(2015) Doris Vandeputte et al.   GUT

Analysis of Bacterial Communities during Clostridium difficile Infection in the Mouse

(2015) Ekaterina G. Semenyuk et al.   INFECTION AND IMMUNITY

Role of colonic microbiota in colorectal carcinogenesis: A systematic review

(2015) Marta Borges Canha   REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS

Antibiotic-Induced Alterations of the Murine Gut Microbiota and Subsequent Effects on Colonization Resistance against Clostridium difficile

(2015) Alyxandria M. Schubert et al.   mBio

Risk factors of Clostridium difficile infections among patients in a university hospital in Shanghai, China

(2014) Haihui Huang et al.   ANAEROBE

Gut Microbiota-Produced Succinate Promotes C. difficile Infection after Antibiotic Treatment or Motility Disturbance

(2014) Jessica A. Ferreyra et al.   Cell Host & Microbe

Role of the Intestinal Microbiota in Resistance to Colonization by Clostridium difficile

(2014) Robert A. Britton et al.   GASTROENTEROLOGY

Effects of bowel cleansing on the intestinal microbiota

(2014) Jonna Jalanka et al.   GUT

Reinforcement of the Intestinal Mucus Layer Protects Against Clostridium difficile Intestinal Injury In Vitro

(2014) Lawrence N. Diebel et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Metabolomics Analysis Identifies Intestinal Microbiota-Derived Biomarkers of Colonization Resistance in Clindamycin-Treated Mice

(2014) Robin L. P. Jump et al.   PLoS One

Microbiome Data Distinguish Patients with Clostridium difficile Infection and Non-C. difficile-Associated Diarrhea from Healthy Controls

(2014) A. M. Schubert et al.   mBio

Development of a Dual-Index Sequencing Strategy and Curation Pipeline for Analyzing Amplicon Sequence Data on the MiSeq Illumina Sequencing Platform

(2013) James J. Kozich et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Complex Interactions Among Diet, Gastrointestinal Transit, and Gut Microbiota in Humanized Mice

(2013) Purna C. Kashyap et al.   GASTROENTEROLOGY

Effect of host defenses on Clostridium difficile toxin–induced intestinal barrier injury

(2013) Alicia Olson et al.   Journal of Trauma and Acute Care Surgery

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ribosomal Database Project: data and tools for high throughput rRNA analysis

(2013) James R. Cole et al.   NUCLEIC ACIDS RESEARCH

Alterations in the Colonic Microbiota in Response to Osmotic Diarrhea

(2013) Gregor Gorkiewicz et al.   PLoS One

Risk factors, preemptive therapy, and antiperistaltic agents forClostridium difficileinfection in cancer patients

(2013) S.G. Krishna et al.   Transplant Infectious Disease

Acetatifactor muris gen. nov., sp. nov., a novel bacterium isolated from the intestine of an obese mouse

(2012) Nora Pfeiffer et al.   ARCHIVES OF MICROBIOLOGY

Colonoscopic versus nasogastric fecal transplantation for the treatment of Clostridium difficile infection: a review and pooled analysis

(2012) R. Postigo et al.   INFECTION

The SILVA ribosomal RNA gene database project: improved data processing and web-based tools

(2012) Christian Quast et al.   NUCLEIC ACIDS RESEARCH

Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice

(2012) Trevor D. Lawley et al.   PLoS Pathogens

Moderate to High Use of Opioid Analgesics Are Associated With an Increased Risk of Clostridium difficile Infection

(2011) Andrea L. Mora et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Development and Validation of a Clostridium difficile Infection Risk Prediction Model

(2011) Erik R. Dubberke et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Introducing mothur: Open-Source, Platform-Independent, Community-Supported Software for Describing and Comparing Microbial Communities

(2009) P. D. Schloss et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY