标题
Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street
作者
关键词
Metabolic diseases, Branched-chain amino acids, Lipogenesis, Nutrition, Insulin resistance
出版物
Molecular Metabolism
Volume 52, Issue -, Pages 101261
出版商
Elsevier BV
发表日期
2021-05-25
DOI
10.1016/j.molmet.2021.101261
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- BCAA Supplementation in Mice with Diet-Induced Obesity Alters the Metabolome Without Impairing Glucose Homeostasis
- (2021) Jennifer Lee et al. ENDOCRINOLOGY
- Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart
- (2021) Jacquelyn M. Walejko et al. Nature Communications
- APN-mediated phosphorylation of BCKDK promotes hepatocellular carcinoma metastasis and proliferation via the ERK signaling pathway
- (2020) Mengying Zhai et al. Cell Death & Disease
- Branched-chain amino acids in disease
- (2019) Phillip J. White et al. SCIENCE
- Nine Amino Acids are Associated with Decreased Insulin Secretion and Elevated Glucose Levels in a 4.6-Year Follow-Up Study of 5,181 Finnish Men
- (2019) Jagadish Vangipurapu et al. DIABETES
- Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance
- (2019) Meiyi Zhou et al. DIABETES
- Cord-Blood Metabolomics: Association with Newborn Anthropometrics and C-Peptide across Ancestries
- (2019) Rachel Kadakia et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Short-term dietary reduction of branched-chain amino acids reduces meal-induced insulin secretion and modifies microbiome composition in type 2 diabetes: a randomized controlled crossover trial
- (2019) Yanislava Karusheva et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- BCAA catabolism in brown fat controls energy homeostasis through SLC25A44
- (2019) Takeshi Yoneshiro et al. NATURE
- Dietary branched-chain amino acid restriction alters fuel selection and reduces triglyceride stores in hearts of Zucker fatty rats
- (2019) Robert W. McGarrah et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase
- (2018) Phillip J. White et al. Cell Metabolism
- Fructose metabolism and metabolic disease
- (2018) Sarah A. Hannou et al. JOURNAL OF CLINICAL INVESTIGATION
- Glucose promotes cell growth by suppressing branched-chain amino acid degradation
- (2018) Dan Shao et al. Nature Communications
- Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids
- (2018) Michael D. Neinast et al. Cell Metabolism
- Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries
- (2018) Rachel Kadakia et al. DIABETOLOGIA
- Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues
- (2018) Martina Wallace et al. Nature Chemical Biology
- Metabolic pathways at the crossroads of diabetes and inborn errors
- (2017) Eric S. Goetzman et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Restoration of metabolic health by decreased consumption of branched-chain amino acids
- (2017) Nicole E. Cummings et al. JOURNAL OF PHYSIOLOGY-LONDON
- Catabolic Defect of Branched-Chain Amino Acids Promotes Heart FailureCLINICAL PERSPECTIVE
- (2016) Haipeng Sun et al. CIRCULATION
- Human gut microbes impact host serum metabolome and insulin sensitivity
- (2016) Helle Krogh Pedersen et al. NATURE
- A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance
- (2016) Cholsoon Jang et al. NATURE MEDICINE
- Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health
- (2016) Luigi Fontana et al. Cell Reports
- Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis
- (2016) Luca A. Lotta et al. PLOS MEDICINE
- Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export
- (2016) Phillip J. White et al. Molecular Metabolism
- Metabolomic Profile Associated With Insulin Resistance and Conversion to Diabetes in the Insulin Resistance Atherosclerosis Study
- (2015) Nicholette D. Palmer et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Metabolic Inflexibility: When Mitochondrial Indecision Leads to Metabolic Gridlock
- (2014) Deborah M. Muoio CELL
- Brain Insulin Lowers Circulating BCAA Levels by Inducing Hepatic BCAA Catabolism
- (2014) Andrew C. Shin et al. Cell Metabolism
- β-Aminoisobutyric Acid Induces Browning of White Fat and Hepatic β-Oxidation and Is Inversely Correlated with Cardiometabolic Risk Factors
- (2014) Lee D. Roberts et al. Cell Metabolism
- Impaired Adiponectin Signaling Contributes to Disturbed Catabolism of Branched-Chain Amino Acids in Diabetic Mice
- (2014) Kun Lian et al. DIABETES
- Branched-chain amino acid metabolism: from rare Mendelian diseases to more common disorders
- (2014) L. C. Burrage et al. HUMAN MOLECULAR GENETICS
- Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase
- (2014) Shih-Chia Tso et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity
- (2013) Denise E. Lackey et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness
- (2013) Bryan C. Batch et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Race and Sex Differences in Small-Molecule Metabolites and Metabolic Hormones in Overweight and Obese Adults
- (2013) Mahesh J. Patel et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain -ketoacid dehydrogenase kinase
- (2013) S.-C. Tso et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice
- (2013) V. K. Ridaura et al. SCIENCE
- Branched-chain amino acids alter neurobehavioral function in rats
- (2012) Anna Coppola et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Muscle-Specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility
- (2012) Deborah M. Muoio et al. Cell Metabolism
- Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance
- (2012) Christopher B. Newgard Cell Metabolism
- Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in Humans
- (2012) Susan Cheng et al. CIRCULATION
- Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss
- (2011) S. H. Shah et al. DIABETOLOGIA
- Metabolite profiles and the risk of developing diabetes
- (2011) Thomas J Wang et al. NATURE MEDICINE
- Dietary Leucine - An Environmental Modifier of Insulin Resistance Acting on Multiple Levels of Metabolism
- (2011) Yazmin Macotela et al. PLoS One
- Differential Metabolic Impact of Gastric Bypass Surgery Versus Dietary Intervention in Obese Diabetic Subjects Despite Identical Weight Loss
- (2011) B. Laferrere et al. Science Translational Medicine
- Multi-tissue, selective PPARγ modulation of insulin sensitivity and metabolic pathways in obese rats
- (2010) Gene Hsiao et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Association of a Peripheral Blood Metabolic Profile With Coronary Artery Disease and Risk of Subsequent Cardiovascular Events
- (2010) Svati H. Shah et al. Circulation-Cardiovascular Genetics
- Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men
- (2010) E. S. Tai et al. DIABETOLOGIA
- Adipose Tissue Branched Chain Amino Acid (BCAA) Metabolism Modulates Circulating BCAA Levels
- (2010) Mark A. Herman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
- (2009) Christopher B. Newgard et al. Cell Metabolism
- Relationships Between Circulating Metabolic Intermediates and Insulin Action in Overweight to Obese, Inactive Men and Women
- (2009) K. M. Huffman et al. DIABETES CARE
- Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
- (2008) Timothy R. Koves et al. Cell Metabolism
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