Gsα-dependent signaling is required for postnatal establishment of a functional β-cell mass

Insulin: The Friend and the Foe in the Development of Type 2 Diabetes Mellitus

(2020) Nadia Rachdaoui   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcription factor Creb3l1 regulates the synthesis of prohormone convertase enzyme PC1/3 in endocrine cells

(2020) Mingkwan Greenwood et al.   JOURNAL OF NEUROENDOCRINOLOGY

Dual Effect of Raptor on Neonatal β Cell Proliferation and Identity Maintenance

(2019) Yanqiu Wang et al.   DIABETES

Glucagon-like peptide 1 (GLP-1)

(2019) T.D. Müller et al.   Molecular Metabolism

GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells

(2019) Jalal Taneera et al.   GENE

β-Cell Maturation and Identity in Health and Disease

(2019) Salinno et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca 2+ Sensitivity of Insulin Secretion Vesicles

(2018) Chen Huang et al.   DEVELOPMENTAL CELL

Insulin Receptor Isoforms in Physiology and Disease: An Updated View

(2017) Antonino Belfiore et al.   ENDOCRINE REVIEWS

All mixed up: defining roles for β-cell subtypes in mature islets

(2017) Jennifer S.E. Liu et al.   GENES & DEVELOPMENT

Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling

(2017) Chunhua Dai et al.   JOURNAL OF CLINICAL INVESTIGATION

Late-stage differentiation of embryonic pancreatic β-cells requires Jarid2

(2017) Sara Cervantes et al.   Scientific Reports

ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cells

(2016) Eiji Yoshihara et al.   Cell Metabolism

Phosphorylated Ribosomal Protein S6 Is Required for Akt-Driven Hyperplasia and Malignant Transformation, but Not for Hypertrophy, Aneuploidy and Hyperfunction of Pancreatic β-Cells

(2016) Avigail Dreazen Wittenberg et al.   PLoS One

Insulin receptor alternative splicing is regulated by insulin signaling and modulates beta cell survival

(2016) Pushkar Malakar et al.   Scientific Reports

Weaning Triggers a Maturation Step of Pancreatic β Cells

(2015) Miri Stolovich-Rain et al.   DEVELOPMENTAL CELL

Human β-Cell Proliferation and Intracellular Signaling: Part 3

(2015) Andrew F. Stewart et al.   DIABETES

TCF1 links GIPR signaling to the control of beta cell function and survival

(2015) Jonathan E Campbell et al.   NATURE MEDICINE

Diabetes mellitus—advances and challenges in human β-cell proliferation

(2015) Peng Wang et al.   Nature Reviews Endocrinology

Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion

(2015) Miles Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Feedback Inhibition of CREB Signaling Promotes Beta Cell Dysfunction in Insulin Resistance

(2015) Emilie Blanchet et al.   Cell Reports

Impaired Islet Function in Commonly Used Transgenic Mouse Lines due to Human Growth Hormone Minigene Expression

(2014) Bas Brouwers et al.   Cell Metabolism

The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth

(2014) Yan Hang et al.   DIABETES

Ins1 Cre knock-in mice for beta cell-specific gene recombination

(2014) Bernard Thorens et al.   DIABETOLOGIA

MafA is critical for maintenance of the mature beta cell phenotype in mice

(2014) Wataru Nishimura et al.   DIABETOLOGIA

CREB mediates the insulinotropic and anti-apoptotic effects of GLP-1 signaling in adult mouse β-cells

(2014) Soona Shin et al.   Molecular Metabolism

Direct Autocrine Action of Insulin on  -Cells: Does It Make Physiological Sense?

(2013) C. J. Rhodes et al.   DIABETES

Osteocalcin Promotes  -Cell Proliferation During Development and Adulthood Through Gprc6a

(2013) J. Wei et al.   DIABETES

Adenosine Signaling Promotes Regeneration of Pancreatic β Cells In Vivo

(2012) Olov Andersson et al.   Cell Metabolism

Neonatal β Cell Development in Mice and Humans Is Regulated by Calcineurin/NFAT

(2012) William R. Goodyer et al.   DEVELOPMENTAL CELL

The role of Raf-1 kinase inhibitor protein in the regulation of pancreatic beta cell proliferation in mice

(2012) F. N. Pardo et al.   DIABETOLOGIA

Cell signalling in insulin secretion: the molecular targets of ATP, cAMP and sulfonylurea

(2012) S. Seino   DIABETOLOGIA

Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3

(2012) Barak Blum et al.   NATURE BIOTECHNOLOGY

Roles and Regulation of the Transcription Factor CREB in Pancreatic β -Cells

(2011) Stephane Dalle et al.   Current Molecular Pharmacology

Vasoactive Intestinal Peptide-Null Mice Demonstrate Enhanced Sweet Taste Preference, Dysglycemia, and Reduced Taste Bud Leptin Receptor Expression

(2010) B. Martin et al.   DIABETES

Brain expression of Cre recombinase driven by pancreas-specific promoters

(2010) Junghun Song et al.   GENESIS

Glucagon-like Peptide-1 Increases β-Cell Glucose Competence and Proliferation by Translational Induction of Insulin-like Growth Factor-1 Receptor Expression

(2010) Marion Cornu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EPAC proteins transduce diverse cellular actions of cAMP

(2009) Gillian Borland et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glucagon-Like Peptide-1 Protects  -Cells Against Apoptosis by Increasing the Activity of an Igf-2/Igf-1 Receptor Autocrine Loop

(2009) M. Cornu et al.   DIABETES

Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease

(2009) Antonino Belfiore et al.   ENDOCRINE REVIEWS

Epac and PKA: a tale of two intracellular cAMP receptors

(2008) Xiaodong Cheng et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Exendin-4 Stimulation of Cyclin A2 in  -Cell Proliferation

(2008) W.-J. Song et al.   DIABETES