Insulin receptor alternative splicing is regulated by insulin signaling and modulates beta cell survival

Metabolic, anabolic, and mitogenic insulin responses: A tissue-specific perspective for insulin receptor activators

(2015) Daniel H. Bedinger et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Mnk2 Alternative Splicing Modulates the p38-MAPK Pathway and Impacts Ras-Induced Transformation

(2014) Avraham Maimon et al.   Cell Reports

Mitogenic Insulin Receptor-A Is Overexpressed in Human Hepatocellular Carcinoma due to EGFR-Mediated Dysregulation of RNA Splicing Factors

(2013) Hamza Chettouh et al.   CANCER RESEARCH

Type 2 Diabetes and Congenital Hyperinsulinism Cause DNA Double-Strand Breaks and p53 Activity in β Cells

(2013) Sharona Tornovsky-Babeay et al.   Cell Metabolism

Direct Autocrine Action of Insulin on  -Cells: Does It Make Physiological Sense?

(2013) C. J. Rhodes et al.   DIABETES

Adipose tissue INSR splicing in humans associates with fasting insulin level and is regulated by weight loss

(2013) Dorota Kaminska et al.   DIABETOLOGIA

Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron

(2013) Gloria V. Echeverria et al.   NUCLEIC ACIDS RESEARCH

Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

(2011) Emilyn U. Alejandro et al.   FASEB JOURNAL

hnRNP A1 and hnRNP F Modulate the Alternative Splicing of Exon 11 of the Insulin Receptor Gene

(2011) Indrani Talukdar et al.   PLoS One

Muscleblind-like 1 (Mbnl1) Promotes Insulin Receptor Exon 11 Inclusion via Binding to a Downstream Evolutionarily Conserved Intronic Enhancer

(2010) Supriya Sen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin enhances glucose-stimulated insulin secretion in healthy humans

(2010) C. Bouche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin Stimulates Primary β-Cell Proliferation via Raf-1 Kinase

(2008) Jennifer L. Beith et al.   ENDOCRINOLOGY

SRp20 and CUG-BP1 Modulate Insulin Receptor Exon 11 Alternative Splicing

(2008) S. Sen et al.   MOLECULAR AND CELLULAR BIOLOGY