Mitochondrial Quality Control: A Pathophysiological Mechanism and Therapeutic Target for Stroke

Tyrosine kinase Fyn promotes apoptosis after intracerebral hemorrhage in rats by activating Drp1 signaling

(2021) Li Zhang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Ceria nanoparticles ameliorate white matter injury after intracerebral hemorrhage: microglia-astrocyte involvement in remyelination

(2021) Jingwei Zheng et al.   Journal of Neuroinflammation

iTRAQ-Based Quantitative Proteomics Indicated Nrf2/OPTN-Mediated Mitophagy Inhibits NLRP3 Inflammasome Activation after Intracerebral Hemorrhage

(2021) Yijun Cheng et al.   Oxidative Medicine and Cellular Longevity

Neurovascular Units and Neural-Glia Networks in Intracerebral Hemorrhage: from Mechanisms to Translation

(2021) Qing Sun et al.   Translational Stroke Research

Blood–Brain Barrier and Neurovascular Unit In Vitro Models for Studying Mitochondria-Driven Molecular Mechanisms of Neurodegeneration

(2021) Alla B. Salmina et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Microglial PGC-1α protects against ischemic brain injury by suppressing neuroinflammation

(2021) Bin Han et al.   Genome Medicine

Cx32 inhibits the autophagic effect of Nur77 in SH-SY5Y cells and rat brain with ischemic stroke

(2021) Fengfeng Ping et al.   Aging-US

Nuclear receptor Nur77: its role in chronic inflammatory diseases

(2021) Sanne C. Lith et al.   Essays in Biochemistry

Mitochondrial fusion and fission: The fine‐tune balance for cellular homeostasis

(2021) Mary Adebayo et al.   FASEB JOURNAL

Mitochondrial fusion and fission are required for proper mitochondrial function and cell proliferation in fission yeast

(2021) Fenfen Dong et al.   FEBS Journal

Loss of MIC60 Aggravates Neuronal Death by Inducing Mitochondrial Dysfunction in a Rat Model of Intracerebral Hemorrhage

(2021) Ruming Deng et al.   MOLECULAR NEUROBIOLOGY

Supplemental N-3 Polyunsaturated Fatty Acids Limit A1-Specific Astrocyte Polarization via Attenuating Mitochondrial Dysfunction in Ischemic Stroke in Mice

(2021) Jun Cao et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial dysfunction associated with autophagy and mitophagy in cerebrospinal fluid cells of patients with delayed cerebral ischemia following subarachnoid hemorrhage

(2021) Dong Hyuk Youn et al.   Scientific Reports

A Novel Plant-Produced Asialo-rhuEPO Protects Brain from Ischemic Damage Without Erythropoietic Action

(2021) Maotao He et al.   Translational Stroke Research

Crosstalk Between Dysfunctional Mitochondria and Inflammation in Glaucomatous Neurodegeneration

(2021) Assraa Hassan Jassim et al.   Frontiers in Pharmacology

HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia

(2020) Shutian Zhang et al.   Journal of Neuroinflammation

Deletion of a neuronal Drp1 activator protects against cerebral ischemia

(2020) Kyle H. Flippo et al.   JOURNAL OF NEUROSCIENCE

The cell biology of mitochondrial membrane dynamics

(2020) Marta Giacomello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recombinant Adiponectin Peptide Ameliorates Brain Injury Following Intracerebral Hemorrhage by Suppressing Astrocyte-Derived Inflammation via the Inhibition of Drp1-Mediated Mitochondrial Fission

(2020) Xun Wu et al.   Translational Stroke Research

Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane

(2020) Yifan Ge et al.   eLife

Dimerization of mitophagy receptor BNIP3L/NIX is essential for recruitment of autophagic machinery

(2020) Mija Marinković et al.   Autophagy

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner

(2020) Alex P. Seabright et al.   FASEB JOURNAL

The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress

(2020) Hakjoo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial fragmentation enables localized signaling required for cell repair

(2020) Adam Horn et al.   JOURNAL OF CELL BIOLOGY

PARL Protease: A Glimpse at Intramembrane Proteolysis in the Inner Mitochondrial Membrane

(2020) Laine Lysyk et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative Middle-Down MS Analysis of Parkin-Mediated Ubiquitin Chain Assembly

(2020) Kirandeep K. Deol et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The combination of Panax ginseng and Angelica sinensis alleviates ischemia brain injury by suppressing NLRP3 inflammasome activation and microglial pyroptosis

(2020) Jia Hu et al.   PHYTOMEDICINE

Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways

(2020) Chenyang Duan et al.   Cell Death & Disease

Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function

(2020) Yongxing Lai et al.   Redox Biology

PINK 1 phosphorylates Drp1 S616 to regulate mitophagy‐independent mitochondrial dynamics

(2020) Hailong Han et al.   EMBO REPORTS

Rehmapicroside ameliorates cerebral ischemia-reperfusion injury via attenuating peroxynitrite-mediated mitophagy activation

(2020) Yifan Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive Rats

(2020) Carla L. Busceti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy

(2020) Koji Yamano et al.   JOURNAL OF CELL BIOLOGY

Interaction of Microglia and Astrocytes in the Neurovascular Unit

(2020) Li-rong Liu et al.   Frontiers in Immunology

Mitophagy, Mitochondrial Homeostasis, and Cell Fate

(2020) Kaili Ma et al.   Frontiers in Cell and Developmental Biology

Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of parkin-mediated mitophagy in in-vitro and in-vivo models of Parkinson disease

(2020) Sahabuddin Ahmed et al.   BRAIN BEHAVIOR AND IMMUNITY

Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity

(2020) Juan Tur et al.   Cell Reports

Mitochondrial Dysfunction and Alzheimer’s Disease: Role of Microglia

(2020) Ishan Agrawal et al.   Frontiers in Aging Neuroscience

Opa1 Reduces Hypoxia-Induced Cardiomyocyte Death by Improving Mitochondrial Quality Control

(2020) Ting Xin et al.   Frontiers in Cell and Developmental Biology

Mitochondrial Safeguard: a stress response that offsets extreme fusion and protects respiratory function via flickering‐induced Oma1 activation

(2020) Daisuke Murata et al.   EMBO JOURNAL

Mitophagy and the Brain

(2020) Natalie S. Swerdlow et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial quality control in kidney injury and repair

(2020) Chengyuan Tang et al.   Nature Reviews Nephrology

A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy

(2020) Jia-Li Chen et al.   NEUROPHARMACOLOGY

Protective Effects of ShcA Protein Silencing for Photothrombotic Cerebral Infarction

(2020) Jeong-Ah Hwang et al.   Translational Stroke Research

FUNDC1-dependent mitophagy induced by tPA protects neurons against cerebral ischemia-reperfusion injury

(2020) Ying Cai et al.   Redox Biology

Lessons from the Discovery of Mitochondrial Fragmentation (Fission): A Review and Update

(2019) Dmitry Zorov et al.   Cells

Ultrastructure and dynamics of the actin−myosin II cytoskeleton during mitochondrial fission

(2019) Changsong Yang et al.   NATURE CELL BIOLOGY

Mitophagy Reduces Oxidative Stress Via Keap1 (Kelch-Like Epichlorohydrin-Associated Protein 1)/Nrf2 (Nuclear Factor-E2-Related Factor 2)/PHB2 (Prohibitin 2) Pathway After Subarachnoid Hemorrhage in Rats

(2019) Tongyu Zhang et al.   STROKE

PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis

(2019) Chaojun Yan et al.   Autophagy

Global brain inflammation in stroke

(2019) Kaibin Shi et al.   LANCET NEUROLOGY

Atractylenolide III ameliorates cerebral ischemic injury and neuroinflammation associated with inhibiting JAK2/STAT3/Drp1-dependent mitochondrial fission in microglia

(2019) Kecheng Zhou et al.   PHYTOMEDICINE

The emerging, multifaceted role of mitophagy in cancer and cancer therapeutics

(2019) Debasna P. Panigrahi et al.   SEMINARS IN CANCER BIOLOGY

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

(2019) Amit U. Joshi et al.   NATURE NEUROSCIENCE

Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity

(2019) Xuemei Zong et al.   Translational Stroke Research

Pharmacological restoration of autophagy reduces hypertension-related stroke occurrence

(2019) Maurizio Forte et al.   Autophagy

Mitochondrial E3 ubiquitin ligase 1 promotes brain injury by disturbing mitochondrial dynamics in a rat model of ischemic stroke

(2019) Kai-Di Ren et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mitochondria as multifaceted regulators of cell death

(2019) Florian J. Bock et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Electroacupuncture ameliorates neuronal injury by Pink1/Parkin-mediated mitophagy clearance in cerebral ischemia-reperfusion

(2019) Huanyuan Wang et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Mitophagy, Mitochondrial Dynamics, and Homeostasis in Cardiovascular Aging

(2019) Ne N. Wu et al.   Oxidative Medicine and Cellular Longevity

Completion of BAX recruitment correlates with mitochondrial fission during apoptosis

(2019) M. E. Maes et al.   Scientific Reports

Neurovascular Unit as a Source of Ischemic Stroke Biomarkers—Limitations of Experimental Studies and Perspectives for Clinical Application

(2019) Aleksandra Steliga et al.   Translational Stroke Research

Functional morphology of the blood–brain barrier in health and disease

(2018) Stefan Liebner et al.   ACTA NEUROPATHOLOGICA

Mitophagy is activated in brain damage induced by cerebral ischemia and reperfusion via the PINK1/Parkin/p62 signalling pathway

(2018) Rui Lan et al.   BRAIN RESEARCH BULLETIN

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Mitochondrial dynamics: overview of molecular mechanisms

(2018) Lisa Tilokani et al.   Essays in Biochemistry

Photobiomodulation for Global Cerebral Ischemia: Targeting Mitochondrial Dynamics and Functions

(2018) Ruimin Wang et al.   MOLECULAR NEUROBIOLOGY

Inhibition of Peroxynitrite-Induced Mitophagy Activation Attenuates Cerebral Ischemia-Reperfusion Injury

(2018) Jinghan Feng et al.   MOLECULAR NEUROBIOLOGY

Cargo recognition and degradation by selective autophagy

(2018) Damián Gatica et al.   NATURE CELL BIOLOGY

Building and decoding ubiquitin chains for mitophagy

(2018) J. Wade Harper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Astrocyte reactivity and astrogliosis after spinal cord injury

(2018) Seiji Okada et al.   NEUROSCIENCE RESEARCH

Phosphatidic Acid and Cardiolipin Coordinate Mitochondrial Dynamics

(2018) Shoichiro Kameoka et al.   TRENDS IN CELL BIOLOGY

Dynamic clustering of dynamin-amphiphysin helices regulates membrane constriction and fission coupled with GTP hydrolysis

(2018) Tetsuya Takeda et al.   eLife

Ketogenic Diet Improves Brain Ischemic Tolerance and Inhibits NLRP3 Inflammasome Activation by Preventing Drp1-Mediated Mitochondrial Fission and Endoplasmic Reticulum Stress

(2018) Min Guo et al.   Frontiers in Molecular Neuroscience

MFN2 retrotranslocation boosts mitophagy by uncoupling mitochondria from the ER

(2018) Gian-Luca McLelland et al.   Autophagy

Heat Shock Protein B8 (HSPB8) Reduces Oxygen-Glucose Deprivation/Reperfusion Injury via the Induction of Mitophagy

(2018) Fazhao Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission

(2018) Kyle H. Flippo et al.   JOURNAL OF NEUROSCIENCE

Structural basis of mitochondrial receptor binding and constriction by DRP1

(2018) Raghav Kalia et al.   NATURE

Parkin and PINK1 mitigate STING-induced inflammation

(2018) Danielle A. Sliter et al.   NATURE

HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα

(2018) Anthea Di Rita et al.   Nature Communications

Hyperglycemia abolished Drp-1-mediated mitophagy at the early stage of cerebral ischemia

(2018) Wei Zuo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Gregory A Roth et al.   LANCET

Hypoxia-reoxygenation of primary astrocytes results in a redistribution of mitochondrial size and mitophagy

(2018) Dominic D. Quintana et al.   MITOCHONDRION

Mitochondrial dynamics: Biological roles, molecular machinery, and related diseases

(2018) Ayman W. El-Hattab et al.   MOLECULAR GENETICS AND METABOLISM

Therapeutic effects of melatonin on cerebral ischemia reperfusion injury: Role of Yap-OPA1 signaling pathway and mitochondrial fusion

(2018) Na Wei et al.   BIOMEDICINE & PHARMACOTHERAPY

Baicalin attenuates in vivo and in vitro hyperglycemia-exacerbated ischemia/reperfusion injury by regulating mitochondrial function in a manner dependent on AMPK

(2017) Shanshan Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The short variant of the mitochondrial dynamin OPA1 maintains mitochondrial energetics and cristae structure

(2017) Hakjoo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

(2017) Jonathon L. Burman et al.   JOURNAL OF CELL BIOLOGY

Cerebrovascular function and mitochondrial bioenergetics after ischemia-reperfusion in male rats

(2017) Ibolya Rutkai et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress

(2017) Qiao Huang et al.   MOLECULAR NEUROBIOLOGY

Mitochondrial Quality Control and Disease: Insights into Ischemia-Reperfusion Injury

(2017) Anthony R. Anzell et al.   MOLECULAR NEUROBIOLOGY

OPA1 and cardiolipin team up for mitochondrial fusion

(2017) Raymond Liu et al.   NATURE CELL BIOLOGY

The NLRP3 inflammasome in acute myocardial infarction

(2017) Stefano Toldo et al.   Nature Reviews Cardiology

Control of mitochondrial physiology and cell death by the Bcl-2 family proteins Bax and Bok

(2017) Beatrice D'Orsi et al.   NEUROCHEMISTRY INTERNATIONAL

Inflammation and mitochondrial dysfunction: A vicious circle in neurodegenerative disorders?

(2017) Jack van Horssen et al.   NEUROSCIENCE LETTERS

How AMPK and PKA Interplay to Regulate Mitochondrial Function and Survival in Models of Ischemia and Diabetes

(2017) Jingdian Zhang et al.   Oxidative Medicine and Cellular Longevity

YiQiFuMai Powder Injection Protects against Ischemic Stroke via Inhibiting Neuronal Apoptosis and PKCδ/Drp1-Mediated Excessive Mitochondrial Fission

(2017) Yingqiong Xu et al.   Oxidative Medicine and Cellular Longevity

Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms

(2017) Jesse S. Kerr et al.   TRENDS IN NEUROSCIENCES

Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation

(2017) Shenglong Cao et al.   Scientific Reports

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

(2016) Lena Pernas et al.   Annual Review of Physiology

Mitochondrial dynamics during cell cycling

(2016) Rostyslav Horbay et al.   APOPTOSIS

Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy

(2016) Ming Chen et al.   Autophagy

Drp-1, a potential therapeutic target for brain ischaemic stroke

(2016) W Zuo et al.   BRITISH JOURNAL OF PHARMACOLOGY

The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease

(2016) K. Atkins et al.   CLINICAL SCIENCE

Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation

(2016) Thanh Ngoc Nguyen et al.   JOURNAL OF CELL BIOLOGY

Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

(2016) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

OPA1 processing in cell death and disease – the long and short of it

(2016) Thomas MacVicar et al.   JOURNAL OF CELL SCIENCE

Reversible Disruption of Neuronal Mitochondria by Ischemic and Traumatic Injury Revealed by Quantitative Two-Photon Imaging in the Neocortex of Anesthetized Mice

(2016) Mikhail Kislin et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial E3 ubiquitin ligase 1: A key enzyme in regulation of mitochondrial dynamics and functions

(2016) Jun Peng et al.   MITOCHONDRION

Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein

(2016) Shan Xu et al.   MOLECULAR BIOLOGY OF THE CELL

The Injury and Therapy of Reactive Oxygen Species in Intracerebral Hemorrhage Looking at Mitochondria

(2016) Jie Qu et al.   Oxidative Medicine and Cellular Longevity

Neuroprotective coordination of cell mitophagy by the ATPase Inhibitory Factor 1

(2016) Ivana Matic et al.   PHARMACOLOGICAL RESEARCH

Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke

(2016) Zhongwu Liu et al.   PROGRESS IN NEUROBIOLOGY

A mitofusin-dependent docking ring complex triggers mitochondrial fusion in vitro

(2016) Tobias Brandt et al.   eLife

Mitochondrial quality control pathways as determinants of metabolic health

(2015) Ntsiki M. Held et al.   BIOESSAYS

Mitochondrial division and fusion in metabolism

(2015) Madhuparna Roy et al.   CURRENT OPINION IN CELL BIOLOGY

Mitofusin 2 ameliorates hypoxia-induced apoptosis via mitochondrial function and signaling pathways

(2015) Cheng Peng et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1

(2015) Raymond Liu et al.   MOLECULAR BIOLOGY OF THE CELL

The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

(2015) Jin-Mi Heo et al.   MOLECULAR CELL

MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death

(2015) Julien Prudent et al.   MOLECULAR CELL

Unknown

(2015) Yao Di et al.   MOLECULAR MEDICINE

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Mitochondrial control by DRP1 in brain tumor initiating cells

(2015) Qi Xie et al.   NATURE NEUROSCIENCE

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

(2015) T. Wai et al.   SCIENCE

Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons

(2015) L Y Shields et al.   Cell Death & Disease

Mitochondrial dynamics and mitochondrial quality control

(2015) Hong-Min Ni et al.   Redox Biology

Rapamycin attenuates mitochondrial dysfunction via activation of mitophagy in experimental ischemic stroke

(2014) Qiang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Voltage-dependent anion channels (VDACs) promote mitophagy to protect neuron from death in an early brain injury following a subarachnoid hemorrhage in rats

(2014) Jian Li et al.   BRAIN RESEARCH

BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke

(2014) Ruo-Yang Shi et al.   CNS Neuroscience & Therapeutics

Amelioration of Ischemic Mitochondrial Injury and Bax-Dependent Outer Membrane Permeabilization by Mdivi-1

(2014) Yan-Xin Zhao et al.   CNS Neuroscience & Therapeutics

Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death

(2014) A. Martorell-Riera et al.   EMBO JOURNAL

Bax Interacting Factor-1 Promotes Survival and Mitochondrial Elongation in Neurons

(2014) D. B. Wang et al.   JOURNAL OF NEUROSCIENCE

Ubiquitin is phosphorylated by PINK1 to activate parkin

(2014) Fumika Koyano et al.   NATURE

Mitochondrial dynamics and inheritance during cell division, development and disease

(2014) Prashant Mishra et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage

(2014) Wei Zuo et al.   NEUROPHARMACOLOGY

Modulation of Mitochondrial Function and Autophagy Mediates Carnosine Neuroprotection Against Ischemic Brain Damage

(2014) Seung-Hoon Baek et al.   STROKE

Protection after stroke: cellular effectors of neurovascular unit integrity

(2014) Rafael Andres Posada-Duque et al.   Frontiers in Cellular Neuroscience

Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells

(2013) Junghyung Park et al.   JOURNAL OF NEUROCHEMISTRY

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

(2013) Oliver C. Losón et al.   MOLECULAR BIOLOGY OF THE CELL

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

(2013) Y. Chen et al.   SCIENCE

Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia

(2012) Pei Wang et al.   Autophagy

Long time-lapse imaging reveals unique features of PARK2/Parkin-mediated mitophagy in mature cortical neurons

(2012) Qian Cai et al.   Autophagy

Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

(2012) Richard F Keep et al.   LANCET NEUROLOGY

Mitochondrial quality control: an integrated network of pathways

(2012) Fabian Fischer et al.   TRENDS IN BIOCHEMICAL SCIENCES

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

The role of mitochondria in apoptosis

(2011) Seon-Yong Jeong et al.   BMB Reports

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

(2011) Xinnan Wang et al.   CELL

Elevated intracellular calcium causes distinct mitochondrial remodelling and calcineurin-dependent fission in astrocytes

(2011) Andrew R. Tan et al.   CELL CALCIUM

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Autophagosome Formation and Molecular Mechanism of Autophagy

(2010) Isei Tanida   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial fission and fusion

(2010) Iain Scott et al.   Essays in Biochemistry

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

(2010) Seok Min Jin et al.   JOURNAL OF CELL BIOLOGY

Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1

(2010) Y.-Y. Park et al.   JOURNAL OF CELL SCIENCE

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

(2008) G. M. Cereghetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA