Mitochondrial Safeguard: a stress response that offsets extreme fusion and protects respiratory function via flickering‐induced Oma1 activation

MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation

(2020) Till Stephan et al.   EMBO JOURNAL

SQSTM1/p62 promotes mitochondrial ubiquitination independently of PINK1 and PRKN/parkin in mitophagy

(2019) Tatsuya Yamada et al.   Autophagy

Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent

(2019) Dane M Wolf et al.   EMBO JOURNAL

The regulation of tumor cell physiology by mitochondrial dynamics

(2018) David F. Kashatus   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease

(2018) Tatsuya Yamada et al.   Cell Metabolism

Ablation of the stress protease OMA1 protects against heart failure in mice

(2018) Rebeca Acin-Perez et al.   Science Translational Medicine

Mitochondrial dynamics: The dynamin superfamily and execution by collusion

(2018) Rajesh Ramachandran   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Phosphatidic Acid and Cardiolipin Coordinate Mitochondrial Dynamics

(2018) Shoichiro Kameoka et al.   TRENDS IN CELL BIOLOGY

Mitochondrial regulation of diabetic vascular disease: an emerging opportunity

(2018) Michael E. Widlansky et al.   Translational Research

Long-Term Potentiation Requires a Rapid Burst of Dendritic Mitochondrial Fission during Induction

(2018) Sai Sachin Divakaruni et al.   NEURON

The constriction and scission machineries involved in mitochondrial fission

(2017) Felix Kraus et al.   JOURNAL OF CELL SCIENCE

Dynamin-Related Protein 1 Deficiency Leads to Receptor-Interacting Protein Kinase 3–Mediated Necroptotic Neurodegeneration

(2016) Tatsuya Yamada et al.   AMERICAN JOURNAL OF PATHOLOGY

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

(2016) Lena Pernas et al.   Annual Review of Physiology

Parkin suppresses Drp1-independent mitochondrial division

(2016) Madhuparna Roy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Histology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in Adults and Children

(2016) David E. Kleiner et al.   Clinics in Liver Disease

Distinct types of protease systems are involved in homeostasis regulation of mitochondrial morphology via balanced fusion and fission

(2016) Shotaro Saita et al.   GENES TO CELLS

OPA1 processing in cell death and disease – the long and short of it

(2016) Thomas MacVicar et al.   JOURNAL OF CELL SCIENCE

Coincident Phosphatidic Acid Interaction Restrains Drp1 in Mitochondrial Division

(2016) Yoshihiro Adachi et al.   MOLECULAR CELL

Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity during Stress

(2016) T. Kelly Rainbolt et al.   Cell Reports

Mitochondrial division and fusion in metabolism

(2015) Madhuparna Roy et al.   CURRENT OPINION IN CELL BIOLOGY

Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons

(2015) L Y Shields et al.   Cell Death & Disease

Flicker-assisted localization microscopy reveals altered mitochondrial architecture in hypertension

(2015) Susan Chalmers et al.   Scientific Reports

Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain

(2014) Yusuke Kageyama et al.   EMBO JOURNAL

Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics

(2014) M. J. Baker et al.   EMBO JOURNAL

Membrane depolarization activates the mitochondrial protease OMA1 by stimulating self-cleavage

(2014) K. Zhang et al.   EMBO REPORTS

Transient Contraction of Mitochondria Induces Depolarization through the Inner Membrane Dynamin OPA1 Protein

(2014) Hakjoo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thei-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

(2014) Ruchika Anand et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial form and function

(2014) Jonathan R. Friedman et al.   NATURE

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

Mechanisms of Mitochondrial Fission and Fusion

(2013) A. M. van der Bliek et al.   Cold Spring Harbor Perspectives in Biology

Transgenic Control of Mitochondrial Fission Induces Mitochondrial Uncoupling and Relieves Diabetic Oxidative Stress

(2012) C. A. Galloway et al.   DIABETES

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

(2012) Pedro M Quirós et al.   EMBO JOURNAL

Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage

(2012) Yusuke Kageyama et al.   JOURNAL OF CELL BIOLOGY

Rational design of true monomeric and bright photoactivatable fluorescent proteins

(2012) Mingshu Zhang et al.   NATURE METHODS

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Mitochondrial dynamics in neurodegeneration

(2012) Kie Itoh et al.   TRENDS IN CELL BIOLOGY

SnapShot: Mitochondrial Dynamics

(2011) Yasushi Tamura et al.   CELL

Loss of Drp1 function alters OPA1 processing and changes mitochondrial membrane organization

(2009) Kristin Möpert et al.   EXPERIMENTAL CELL RESEARCH

Regulation of OPA1 processing and mitochondrial fusion bym-AAA protease isoenzymes and OMA1

(2009) Sarah Ehses et al.   JOURNAL OF CELL BIOLOGY

Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells

(2009) Brian Head et al.   JOURNAL OF CELL BIOLOGY

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

(2009) Junko Wakabayashi et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

(2009) Naotada Ishihara et al.   NATURE CELL BIOLOGY

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL