ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites
出版年份 2021 全文链接
标题
ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites
作者
关键词
Abemaciclib, active metabolites, P-glycoprotein/ABCB1, BCRP/ABCG2, CYP3A, brain penetration, pharmacokinetics
出版物
PHARMACOLOGICAL RESEARCH
Volume -, Issue -, Pages 105954
出版商
Elsevier BV
发表日期
2021-10-26
DOI
10.1016/j.phrs.2021.105954
参考文献
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