P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib
出版年份 2015 全文链接
标题
P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib
作者
关键词
Glioma, Pharmacokinetics, CDK4/6, ABC transporters, Palbociclib
出版物
INVESTIGATIONAL NEW DRUGS
Volume 33, Issue 5, Pages 1012-1019
出版商
Springer Nature
发表日期
2015-06-30
DOI
10.1007/s10637-015-0266-y
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Overcoming the blood–brain tumor barrier for effective glioblastoma treatment
- (2015) O. van Tellingen et al. DRUG RESISTANCE UPDATES
- Palbociclib: First Global Approval
- (2015) Sohita Dhillon DRUGS
- Phase 1/2 study of cyclin-dependent kinase (CDK)4/6 inhibitor palbociclib (PD-0332991) with bortezomib and dexamethasone in relapsed/refractory multiple myeloma
- (2015) Ruben Niesvizky et al. LEUKEMIA & LYMPHOMA
- Abstract C81: BBB efflux pump activity limits brain penetration of palbociclib (PD0332991) in glioblastoma.
- (2014) K. E. Parrish et al. MOLECULAR CANCER THERAPEUTICS
- The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
- (2014) Gang Wu et al. NATURE GENETICS
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- Dual mTORC1 and mTORC2 inhibitor Palomid 529 penetrates the Blood-Brain Barrier without restriction by ABCB1 and ABCG2
- (2013) Fan Lin et al. INTERNATIONAL JOURNAL OF CANCER
- PD-0332991, a CDK4/6 Inhibitor, Significantly Prolongs Survival in a Genetically Engineered Mouse Model of Brainstem Glioma
- (2013) Kelly L. Barton et al. PLoS One
- Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1)
- (2011) G K Schwartz et al. BRITISH JOURNAL OF CANCER
- Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer
- (2011) K. T. Flaherty et al. CLINICAL CANCER RESEARCH
- Improving Cancer Chemotherapy with Modulators of ABC Drug Transporters
- (2011) S. Shukla et al. CURRENT DRUG TARGETS
- Genome-Wide Analyses Identify Recurrent Amplifications of Receptor Tyrosine Kinases and Cell-Cycle Regulatory Genes in Diffuse Intrinsic Pontine Glioma
- (2011) Barbara S. Paugh et al. JOURNAL OF CLINICAL ONCOLOGY
- Pharmacologic Inhibition of Cyclin-Dependent Kinases 4 and 6 Arrests the Growth of Glioblastoma Multiforme Intracranial Xenografts
- (2010) K. Michaud et al. CANCER RESEARCH
- PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel
- (2010) Yong Zhang et al. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
- Prediction of Solubility and Permeability Class Membership: Provisional BCS Classification of the World’s Top Oral Drugs
- (2009) Arik Dahan et al. AAPS Journal
- The biological and clinical role of drug transporters at the intestinal barrier
- (2008) Roos L. Oostendorp et al. CANCER TREATMENT REVIEWS
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started