Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma
出版年份 2022 全文链接
标题
Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma
作者
关键词
-
出版物
ONCOGENE
Volume 41, Issue 8, Pages 1129-1139
出版商
Springer Science and Business Media LLC
发表日期
2022-01-20
DOI
10.1038/s41388-021-02154-0
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Roles of the BAP1 tumor suppressor in cell metabolism
- (2021) Anna Han et al. CANCER RESEARCH
- The AMP‐dependent kinase pathway is upregulated in BAP1 mutant uveal melanoma
- (2021) Vivian Chua et al. Pigment Cell & Melanoma Research
- Single-cell analysis reveals new evolutionary complexity in uveal melanoma
- (2020) Michael A. Durante et al. Nature Communications
- Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours
- (2020) Peter A. Johansson et al. Nature Communications
- Molecular profiling of driver events in metastatic uveal melanoma
- (2020) Joakim Karlsson et al. Nature Communications
- The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells
- (2020) Jie Li et al. Science Signaling
- Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer
- (2020) Michele Carbone et al. Cancer Discovery
- The Latest on Uveal Melanoma Research and Clinical Trials: Updates from the Cure Ocular Melanoma (CURE OM) Science Meeting (2019)
- (2020) Vivian Chua et al. CLINICAL CANCER RESEARCH
- Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis
- (2020) Zhen Cai et al. MOLECULAR CELL
- Metabolic rewiring in the promotion of cancer metastasis: mechanisms and therapeutic implications
- (2020) Qinyao Wei et al. ONCOGENE
- BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors
- (2020) Anna Han et al. ONCOGENE
- Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma
- (2019) Vivian Chua et al. EMBO Molecular Medicine
- Annotation of gene product function from high-throughput studies using the Gene Ontology
- (2019) Helen Attrill et al. Database-The Journal of Biological Databases and Curation
- Inhibition of pyruvate dehydrogenase kinase enhances the antitumor efficacy of oncolytic reovirus
- (2019) Barry E Kennedy et al. CANCER RESEARCH
- Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth
- (2019) Ekta Agarwal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- BAP1 in solid tumors
- (2019) Vincenzo Di Nunno et al. Future Oncology
- The genetic evolution of metastatic uveal melanoma
- (2019) A. Hunter Shain et al. NATURE GENETICS
- Adapt and conquer: Metabolic flexibility in cancer growth, invasion and evasion
- (2019) Peter Kreuzaler et al. Molecular Metabolism
- Combined immune checkpoint blockade for metastatic uveal melanoma: a retrospective, multi-center study
- (2019) Markus V. Heppt et al. Journal for ImmunoTherapy of Cancer
- An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
- (2018) Jianfang Liu et al. CELL
- The contributions of cancer cell metabolism to metastasis
- (2018) Gloria Pascual et al. Disease Models & Mechanisms
- Selumetinib in Combination With Dacarbazine in Patients With Metastatic Uveal Melanoma: A Phase III, Multicenter, Randomized Trial (SUMIT)
- (2018) Richard D. Carvajal et al. JOURNAL OF CLINICAL ONCOLOGY
- Integrating single-cell transcriptomic data across different conditions, technologies, and species
- (2018) Andrew Butler et al. NATURE BIOTECHNOLOGY
- Synergy of Sex Differences in Visceral Fat Measured with CT and Tumor Metabolism Helps Predict Overall Survival in Patients with Renal Cell Carcinoma
- (2018) Gerard K. Nguyen et al. RADIOLOGY
- Punctuated evolution of canonical genomic aberrations in uveal melanoma
- (2018) Matthew G. Field et al. Nature Communications
- PTEN: Tumor Suppressor and Metabolic Regulator
- (2018) Chien-Yu Chen et al. Frontiers in Endocrinology
- BAP1 links metabolic regulation of ferroptosis to tumour suppression
- (2018) Yilei Zhang et al. NATURE CELL BIOLOGY
- Effects of Oncogenic Gαq and Gα11 Inhibition by FR900359 in Uveal Melanoma
- (2018) Dominic Lapadula et al. MOLECULAR CANCER RESEARCH
- Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer
- (2017) Peter W Stacpoole JNCI-Journal of the National Cancer Institute
- Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma
- (2017) Hanyin Cheng et al. MOLECULAR CANCER THERAPEUTICS
- Modulating BAP1 expression affects ROS homeostasis, cell motility and mitochondrial function
- (2017) Lucie Hebert et al. Oncotarget
- Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer
- (2017) Peter W Stacpoole JNCI-Journal of the National Cancer Institute
- Gene of the month:BAP1
- (2016) Ami Wang et al. JOURNAL OF CLINICAL PATHOLOGY
- Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer
- (2016) Josiah E. Hutton et al. MOLECULAR & CELLULAR PROTEOMICS
- Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis
- (2016) Xinjian Li et al. MOLECULAR CELL
- NeuCode Proteomics Reveals Bap1 Regulation of Metabolism
- (2016) Joshua M. Baughman et al. Cell Reports
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer
- (2015) Fanny Dupuy et al. Cell Metabolism
- Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?
- (2015) Wen Zhang et al. International Journal of Biological Sciences
- The pyruvate dehydrogenase complex in cancer: An old metabolic gatekeeper regulated by new pathways and pharmacological agents
- (2015) Elise Saunier et al. INTERNATIONAL JOURNAL OF CANCER
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Lack of BAP1 protein expression in uveal melanoma is associated with increased metastatic risk and has utility in routine prognostic testing
- (2014) H Kalirai et al. BRITISH JOURNAL OF CANCER
- The potential role of O-GlcNAc modification in cancer epigenetics
- (2014) Ewa Forma et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target
- (2014) Nabil Amirouchene-Angelozzi et al. Molecular Oncology
- Disintegration of wheat aleurone structure has an impact on the bioavailability of phenolic compounds and other phytochemicals as evidenced by altered urinary metabolite profile of diet-induced obese mice
- (2014) Jenna Pekkinen et al. Nutrition & Metabolism
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- (2013) Jaekyoung Son et al. NATURE
- O-GlcNAc Transferase/Host Cell Factor C1 Complex Regulates Gluconeogenesis by Modulating PGC-1α Stability
- (2012) Hai-Bin Ruan et al. Cell Metabolism
- Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo
- (2011) Zuzana Zachar et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
- (2010) J. W. Harbour et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started