Lack of BAP1 protein expression in uveal melanoma is associated with increased metastatic risk and has utility in routine prognostic testing

Mutation frequencies of GNAQ, GNA11, BAP1, SF3B1, EIF1AX and TERT in uveal melanoma: detection of an activating mutation in the TERT gene promoter in a single case of uveal melanoma

(2014) M Dono et al.   BRITISH JOURNAL OF CANCER

Single Nucleotide Polymorphism Array Analysis of Uveal Melanomas Reveals That Amplification of CNKSR3 Is Correlated With Improved Patient Survival

(2013) Sarah L. Lake et al.   AMERICAN JOURNAL OF PATHOLOGY

Genetic and clinico-pathologic analysis of metastatic uveal melanoma

(2013) Klaus G Griewank et al.   MODERN PATHOLOGY

Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3

(2013) Marcel Martin et al.   NATURE GENETICS

BAP1 protein loss by immunohistochemistry: A potentially useful tool for prognostic prediction in patients with uveal melanoma

(2013) Akeesha A. Shah et al.   PATHOLOGY

SF3B1 Mutations Are Associated with Alternative Splicing in Uveal Melanoma

(2013) S. J. Furney et al.   Cancer Discovery

A Distinct Subset of Atypical Spitz Tumors is Characterized by BRAF Mutation and Loss of BAP1 Expression

(2012) Thomas Wiesner et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Prognostic significance of chromosome 3 alterations determined by microsatellite analysis in uveal melanoma: a long-term follow-up study

(2012) S Thomas et al.   BRITISH JOURNAL OF CANCER

MRI in the detection of hepatic metastases from high-risk uveal melanoma: a prospective study in 188 patients

(2012) Ernie Marshall et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Intratumor Heterogeneity: Evolution through Space and Time

(2012) C. Swanton   CANCER RESEARCH

Frequent inactivation of the BAP1 gene in epithelioid-type malignant mesothelioma

(2012) Yoshie Yoshikawa et al.   CANCER SCIENCE

BAP1 loss defines a new class of renal cell carcinoma

(2012) Samuel Peña-Llopis et al.   NATURE GENETICS

Histone Deacetylase Inhibitors Induce Growth Arrest and Differentiation in Uveal Melanoma

(2011) S. Landreville et al.   CLINICAL CANCER RESEARCH

Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers

(2011) M. H. Abdel-Rahman et al.   JOURNAL OF MEDICAL GENETICS

Frequency, molecular pathology and potential clinical significance of partial chromosome 3 aberrations in uveal melanoma

(2011) Mohamed H Abdel-Rahman et al.   MODERN PATHOLOGY

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

(2011) Matthew Bott et al.   NATURE GENETICS

Germline mutations in BAP1 predispose to melanocytic tumors

(2011) Thomas Wiesner et al.   NATURE GENETICS

Germline BAP1 mutations predispose to malignant mesothelioma

(2011) Joseph R Testa et al.   NATURE GENETICS

Genotypic Profiling of 452 Choroidal Melanomas with Multiplex Ligation-Dependent Probe Amplification

(2010) B. Damato et al.   CLINICAL CANCER RESEARCH

The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression

(2010) H. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

Mutations inGNA11in Uveal Melanoma

(2010) Catherine D. Van Raamsdonk et al.   NEW ENGLAND JOURNAL OF MEDICINE

Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas

(2010) J. W. Harbour et al.   SCIENCE

The Deubiquitinating Enzyme BAP1 Regulates Cell Growth via Interaction with HCF-1

(2009) Yuichi J. Machida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of C-Terminal Ubiquitin Hydrolase BRCA1-Associated Protein 1 with Cell Cycle Regulator Host Cell Factor 1

(2009) S. Misaghi et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular cytogenetic analysis of archival uveal melanoma with known clinical outcome

(2008) Hanneke W. Mensink et al.   CANCER GENETICS AND CYTOGENETICS

BRCA1-Associated Protein-1 Is a Tumor Suppressor that Requires Deubiquitinating Activity and Nuclear Localization

(2008) K. H. Ventii et al.   CANCER RESEARCH

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

(2008) Catherine D. Van Raamsdonk et al.   NATURE