Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome

(2021) Malte Christoph Rühlemann et al.   NATURE GENETICS

Large-scale association analyses identify host factors influencing human gut microbiome composition

(2021) Alexander Kurilshikov et al.   NATURE GENETICS

A genome-wide association study for gut metagenome in Chinese adults illuminates complex diseases

(2021) Xiaomin Liu et al.   Cell Discovery

Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity

(2021) Janie F. Shelton et al.   NATURE GENETICS

Taxonomic signatures of cause-specific mortality risk in human gut microbiome

(2021) Aaro Salosensaari et al.   Nature Communications

Green Algorithms: Quantifying the Carbon Footprint of Computation

(2021) Loïc Lannelongue et al.   Advanced Science

Proposal for reunification of the genus Raoultella with the genus Klebsiella and reclassification of Raoultella electrica as Klebsiella electrica comb. nov

(2021) Yuanyuan Ma et al.   RESEARCH IN MICROBIOLOGY

Population genomics of Klebsiella pneumoniae

(2020) Kelly L. Wyres et al.   NATURE REVIEWS MICROBIOLOGY

The mutational constraint spectrum quantified from variation in 141,456 humans

(2020) Konrad J. Karczewski et al.   NATURE

A complete domain-to-species taxonomy for Bacteria and Archaea

(2020) Donovan H. Parks et al.   NATURE BIOTECHNOLOGY

Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers

(2020) Nina Mars et al.   NATURE MEDICINE

Blood type and the microbiome- untangling a complex relationship with lessons from pathogens

(2020) Kathleen L Arnolds et al.   CURRENT OPINION IN MICROBIOLOGY

A unified catalog of 204,938 reference genomes from the human gut microbiome

(2020) Alexandre Almeida et al.   NATURE BIOTECHNOLOGY

Genomewide Association Study of Severe Covid-19 with Respiratory Failure

(2020) David Ellinghaus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways

(2020) Michael Jakob Pichler et al.   Nature Communications

Genome-wide associations of human gut microbiome variation and implications for causal inference analyses

(2020) David A. Hughes et al.   Nature Microbiology

Low Prevalence of Lactase Persistence in Bronze Age Europe Indicates Ongoing Strong Selection over the Last 3,000 Years

(2020) Joachim Burger et al.   CURRENT BIOLOGY

Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders

(2020) Jian Yang et al.   Science Advances

Extensive Unexplored Human Microbiome Diversity Revealed by Over 150,000 Genomes from Metagenomes Spanning Age, Geography, and Lifestyle

(2019) Edoardo Pasolli et al.   CELL

The neuroactive potential of the human gut microbiota in quality of life and depression

(2019) Mireia Valles-Colomer et al.   Nature Microbiology

A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

(2019) Andrew J. Schork et al.   NATURE NEUROSCIENCE

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

(2019) Serena Sanna et al.   NATURE GENETICS

The Missing Diversity in Human Genetic Studies

(2019) Giorgio Sirugo et al.   CELL

Differential Responses of Colorectal Cancer Cell Lines to Enterococcus faecalis’ Strains Isolated from Healthy Donors and Colorectal Cancer Patients

(2019) Carolina De Almeida et al.   Journal of Clinical Medicine

Bifidobacterium dentium Fortifies the Intestinal Mucus Layer via Autophagy and Calcium Signaling Pathways

(2019) Melinda A. Engevik et al.   mBio

Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis

(2019) Mikiyasu Sakanaka et al.   Science Advances

Toward universal donor blood: Enzymatic conversion of A and B to O type

(2019) Peter Rahfeld et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deciphering the trophic interaction between Akkermansia muciniphila and the butyrogenic gut commensal Anaerostipes caccae using a metatranscriptomic approach

(2018) Loo Wee Chia et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Keystone taxa as drivers of microbiome structure and functioning

(2018) Samiran Banerjee et al.   NATURE REVIEWS MICROBIOLOGY

dbCAN2: a meta server for automated carbohydrate-active enzyme annotation

(2018) Han Zhang et al.   NUCLEIC ACIDS RESEARCH

Host genetic variation and its microbiome interactions within the Human Microbiome Project

(2018) Raivo Kolde et al.   Genome Medicine

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Function and functional redundancy in microbial systems

(2018) Stilianos Louca et al.   Nature Ecology & Evolution

Social Desirability Trait Influences on Self-Reported Dietary Measures among Diverse Participants in a Multicenter Multiple Risk Factor Trial

(2018) James R. Hebert et al.   JOURNAL OF NUTRITION

Environment dominates over host genetics in shaping human gut microbiota

(2018) Daphna Rothschild et al.   NATURE

A standardized bacterial taxonomy based on genome phylogeny substantially revises the tree of life

(2018) Donovan H Parks et al.   NATURE BIOTECHNOLOGY

Can we predict keystones?

(2018) Lisa Röttjers et al.   NATURE REVIEWS MICROBIOLOGY

Reply to ‘Can we predict microbial keystones?’

(2018) Samiran Banerjee et al.   NATURE REVIEWS MICROBIOLOGY

Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes

(2017)   GLYCOBIOLOGY

Cohort Profile: The National FINRISK Study

(2017) Katja Borodulin et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

Host Genetics and Gut Microbiome: Challenges and Perspectives

(2017) Alexander Kurilshikov et al.   TRENDS IN IMMUNOLOGY

Microbiome Datasets Are Compositional: And This Is Not Optional

(2017) Gregory B. Gloor et al.   Frontiers in Microbiology

Colon cancer and enterococcus bacteremia co-affection: A dangerous alliance

(2017) Raj Amarnani et al.   Journal of Infection and Public Health

ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins

(2016) Emily R. Davenport et al.   BMC GENOMICS

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Genetic Determinants of the Gut Microbiome in UK Twins

(2016) Julia K. Goodrich et al.   Cell Host & Microbe

Gut Microbiota and Celiac Disease

(2016) Giovanni Marasco et al.   DIGESTIVE DISEASES AND SCIENCES

Centrifuge: rapid and sensitive classification of metagenomic sequences

(2016) Daehwan Kim et al.   GENOME RESEARCH

The effect of heritability and host genetics on the gut microbiota and metabolic syndrome

(2016) Mi Young Lim et al.   GUT

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota

(2016) Jun Wang et al.   NATURE GENETICS

The effect of host genetics on the gut microbiome

(2016) Marc Jan Bonder et al.   NATURE GENETICS

Association of host genome with intestinal microbial composition in a large healthy cohort

(2016) Williams Turpin et al.   NATURE GENETICS

Cross-species comparisons of host genetic associations with the microbiome

(2016) Julia K. Goodrich et al.   SCIENCE

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Population-level analysis of gut microbiome variation

(2016) Gwen Falony et al.   SCIENCE

Functional Redundancy-Induced Stability of Gut Microbiota Subjected to Disturbance

(2016) Andrés Moya et al.   TRENDS IN MICROBIOLOGY

Blood type biochemistry and human disease

(2016) D. Rose Ewald et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome

(2016) Hailiang Xie et al.   Cell Systems

High taxonomic variability despite stable functional structure across microbial communities

(2016) Stilianos Louca et al.   Nature Ecology & Evolution

Altered fecal microbiota composition in patients with major depressive disorder

(2015) Haiyin Jiang et al.   BRAIN BEHAVIOR AND IMMUNITY

Genetic Characterization of Human Populations: From ABO to a Genetic Map of the British People

(2015) Walter Bodmer   GENETICS

The gut microbiota and host health: a new clinical frontier

(2015) Julian R Marchesi et al.   GUT

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

The Mediator complex: a central integrator of transcription

(2015) Benjamin L. Allen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Adaptation to Lactose in Lactase Non Persistent People: Effects on Intolerance and the Relationship between Dairy Food Consumption and Evalution of Diseases

(2015) Andrew Szilagyi   Nutrients

Human microbiomes and their roles in dysbiosis, common diseases, and novel therapeutic approaches

(2015) José E. Belizário et al.   Frontiers in Microbiology

Genetic Characterization of Human Populations: From ABO to a Genetic Map of the British People

(2015) Walter Bodmer   GENETICS

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Ecology of bacteria in the human gastrointestinal tract—identification of keystone and foundation taxa

(2015) Pål Trosvik et al.   Microbiome

Mucin glycan foraging in the human gut microbiome

(2015) Louise E. Tailford et al.   Frontiers in Genetics

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Forty-year trends in cardiovascular risk factors in Finland

(2014) K. Borodulin et al.   EUROPEAN JOURNAL OF PUBLIC HEALTH

Seasonal Variation in Human Gut Microbiome Composition

(2014) Emily R. Davenport et al.   PLoS One

Ancestry runs deeper than blood: The evolutionary history ofABOpoints to cryptic variation of functional importance

(2013) Laure Ségurel et al.   BIOESSAYS

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

A conserved Mediator–CDK8 kinase module association regulates Mediator–RNA polymerase II interaction

(2013) Kuang-Lei Tsai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Gut–brain axis: how the microbiome influences anxiety and depression

(2013) Jane A. Foster et al.   TRENDS IN NEUROSCIENCES

G protein-linked signaling pathways in bipolar and major depressive disorders

(2013) Hiroaki Tomita et al.   Frontiers in Genetics

Microbiota from the distal guts of lean and obese adolescents exhibit partial functional redundancy besides clear differences in community structure

(2012) Manuel Ferrer et al.   ENVIRONMENTAL MICROBIOLOGY

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

Complex Carbohydrate Utilization by the Healthy Human Microbiome

(2012) Brandi L. Cantarel et al.   PLoS One

The ABO blood group is a trans-species polymorphism in primates

(2012) L. Segurel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of lactase persistence: an example of human niche construction

(2011) P. Gerbault et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Secretor Genotype (FUT2 gene) Is Strongly Associated with the Composition of Bifidobacteria in the Human Intestine

(2011) Pirjo Wacklin et al.   PLoS One

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

How Accurate Is Self-Reported Dietary Energy Intake?

(2010) Dale A. Schoeller   NUTRITION REVIEWS

A Novel Probiotic Mixture Exerts a Therapeutic Effect on Experimental Autoimmune Encephalomyelitis Mediated by IL-10 Producing Regulatory T Cells

(2010) Shahram Lavasani et al.   PLoS One

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

(2009) M. T. Knuesel et al.   GENES & DEVELOPMENT

Identification of a GH110 Subfamily of α1,3-Galactosidases

(2008) Qiyong P. Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

(2008) Ron Firestein et al.   NATURE

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

(2008) B. L. Cantarel et al.   NUCLEIC ACIDS RESEARCH

Novel Association of ABO Histo-Blood Group Antigen with Soluble ICAM-1: Results of a Genome-Wide Association Study of 6,578 Women

(2008) Guillaume Paré et al.   PLoS Genetics