Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers

Genomic prediction of alcohol-related morbidity and mortality

(2020) Tuomo Kiiskinen et al.   Translational Psychiatry

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors

(2019) Andrew Lee et al.   GENETICS IN MEDICINE

Clinical use of current polygenic risk scores may exacerbate health disparities

(2019) Alicia R. Martin et al.   NATURE GENETICS

10-year performance of four models of breast cancer risk: a validation study

(2019) Mary Beth Terry et al.   LANCET ONCOLOGY

Comparative validation of breast cancer risk prediction models and projections for future risk stratification

(2019) Parichoy Pal Choudhury et al.   JNCI-Journal of the National Cancer Institute

5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study

(2019) Joni V Lindbohm et al.   Lancet Public Health

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

(2018) Fredrick R. Schumacher et al.   NATURE GENETICS

The personal and clinical utility of polygenic risk scores

(2018) Ali Torkamani et al.   NATURE REVIEWS GENETICS

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

(2018) Tyler M Seibert et al.   BMJ-British Medical Journal

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

(2018) Tyler M Seibert et al.   BMJ-British Medical Journal

Long-term Accuracy of Breast Cancer Risk Assessment Combining Classic Risk Factors and Breast Density

(2018) Adam R. Brentnall et al.   JAMA Oncology

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

(2018) Jonas B. Nielsen et al.   NATURE GENETICS

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

(2018) Wei Zhou et al.   NATURE GENETICS

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

(2018) Nasim Mavaddat et al.   AMERICAN JOURNAL OF HUMAN GENETICS

2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2019

(2018)   DIABETES CARE

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary

(2018) Scott M. Grundy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults

(2018) Michael Inouye et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Spencer L James et al.   LANCET

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

(2018) Anubha Mahajan et al.   NATURE GENETICS

Genomic basis of atrial fibrillation

(2017) Aneesh Bapat et al.   HEART

Cohort Profile: The National FINRISK Study

(2017) Katja Borodulin et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Association analysis identifies 65 new breast cancer risk loci

(2017) Kyriaki Michailidou et al.   NATURE

Genetic architecture: the shape of the genetic contribution to human traits and disease

(2017) Nicholas J. Timpson et al.   NATURE REVIEWS GENETICS

Genetic Risk Prediction of Atrial FibrillationClinical Perspective

(2016) Steven A. Lubitz et al.   CIRCULATION

Genomic prediction of coronary heart disease

(2016) Gad Abraham et al.   EUROPEAN HEART JOURNAL

2016 European Guidelines on cardiovascular disease prevention in clinical practice

(2016) Massimo F. Piepoli et al.   EUROPEAN HEART JOURNAL

Developing and evaluating polygenic risk prediction models for stratified disease prevention

(2016) Nilanjan Chatterjee et al.   NATURE REVIEWS GENETICS

Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States

(2016) Paige Maas et al.   JAMA Oncology

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

(2015) Bjarni J. Vilhjálmsson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials

(2015) Jessica L Mega et al.   LANCET

Systematic Review: Family History in Risk Assessment for Common Diseases

(2013) Brenda J. Wilson   ANNALS OF INTERNAL MEDICINE

Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome

(2013) Patrick Royston et al.   BMC Medical Research Methodology

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

(2013) David C. Goff et al.   CIRCULATION

Simple Risk Model Predicts Incidence of Atrial Fibrillation in a Racially and Geographically Diverse Population: the CHARGE‐AF Consortium

(2013) Alvaro Alonso et al.   Journal of the American Heart Association