The effect of host genetics on the gut microbiome

The features of mucosa-associated microbiota in primary sclerosing cholangitis

(2016) J. Torres et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

(2016) Tommi Vatanen et al.   CELL

Genetic Determinants of the Gut Microbiome in UK Twins

(2016) Julia K. Goodrich et al.   Cell Host & Microbe

O-011 Paneth Cell Phenotypes Define a Subtype of Pediatric Crohnʼs Disease Through Alterations in Host-Microbial Interactions

(2016) Ta-Chiang Liu et al.   INFLAMMATORY BOWEL DISEASES

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

(2016) Henner F. Farin et al.   NATURE

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

(2016) Bruno Lamas et al.   NATURE MEDICINE

Understanding human immune function using the resources from the Human Functional Genomics Project

(2016) Mihai G Netea et al.   NATURE MEDICINE

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Microbiota-Mediated Inflammation and Antimicrobial Defense in the Intestine

(2015) Silvia Caballero et al.   Annual Review of Immunology

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

(2015) Robert Caesar et al.   Cell Metabolism

The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood LipidsNovelty and Significance

(2015) Jingyuan Fu et al.   CIRCULATION RESEARCH

C-type lectins in immunity: recent developments

(2015) Ivy M Dambuza et al.   CURRENT OPINION IN IMMUNOLOGY

Genetic and environmental control of host-gut microbiota interactions

(2015) Elin Org et al.   GENOME RESEARCH

Gut microbiota composition associated with stool consistency

(2015) E F Tigchelaar et al.   GUT

Proton pump inhibitors affect the gut microbiome

(2015) Floris Imhann et al.   GUT

Genetic variants associated with motion sickness point to roles for inner ear development, neurological processes and glucose homeostasis

(2015) Bethann S. Hromatka et al.   HUMAN MOLECULAR GENETICS

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

MetaPhlAn2 for enhanced metagenomic taxonomic profiling

(2015) Duy Tin Truong et al.   NATURE METHODS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Interplay between enterobactin, myeloperoxidase and lipocalin 2 regulates E. coli survival in the inflamed gut

(2015) Vishal Singh et al.   Nature Communications

Variable alterations of the microbiota, without metabolic or immunological change, following faecal microbiota transplantation in patients with chronic pouchitis

(2015) J. Landy et al.   Scientific Reports

Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics

(2015) Ettje F Tigchelaar et al.   BMJ Open

Genome-Wide Association Studies of the Human Gut Microbiota

(2015) Emily R. Davenport et al.   PLoS One

Small intestinal permeability is increased in diarrhoea predominant IBS, while alterations in gastroduodenal permeability in all IBS subtypes are largely attributable to confounders

(2014) Z. Mujagic et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

(2014) Dirk Gevers et al.   Cell Host & Microbe

An Unconventional KITENIN/ErbB4-Mediated Downstream Signal of EGF Upregulates c-Jun and the Invasiveness of Colorectal Cancer Cells

(2014) J. A. Bae et al.   CLINICAL CANCER RESEARCH

Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands’

(2014) Patrick Deelen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Bacterial protein signals are associated with Crohn’s disease

(2014) Catherine Juste et al.   GUT

TheATG16L1–T300Aallele impairs clearance of pathosymbionts in the inflamed ileal mucosa of Crohn's disease patients

(2014) Mehdi Sadaghian Sadabad et al.   GUT

DAP1, a Negative Regulator of Autophagy, Controls SubAB-Mediated Apoptosis and Autophagy

(2014) Kinnosuke Yahiro et al.   INFECTION AND IMMUNITY

Whole-genome sequence variation, population structure and demographic history of the Dutch population

(2014) Laurent C Francioli et al.   NATURE GENETICS

Gene Ontology Consortium: going forward

(2014)   NUCLEIC ACIDS RESEARCH

Complex host genetics influence the microbiome in inflammatory bowel disease

(2014) Dan Knights et al.   Genome Medicine

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5

(2014) Stephanie Reikine et al.   Frontiers in Immunology

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

(2013) Brian W. Parks et al.   Cell Metabolism

Crohn's Disease–Associated Adherent Invasive Escherichia coli Modulate Levels of microRNAs in Intestinal Epithelial Cells to Reduce Autophagy

(2013) Hang Thi Thu Nguyen et al.   GASTROENTEROLOGY

ZNRF3 acts as a tumour suppressor by the Wnt signalling pathway in human gastric adenocarcinoma

(2013) Yehui Zhou et al.   JOURNAL OF MOLECULAR HISTOLOGY

Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico

(2013)   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

(2013) Klaus Bønnelykke et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Relative validity of the food frequency questionnaire used to assess dietary intake in the Leiden Longevity Study

(2013) Martinette T Streppel et al.   Nutrition Journal

Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens

(2013) Xiaoming Jia et al.   PLoS One

Characterization of the Gut-Associated Microbiome in Inflammatory Pouch Complications Following Ileal Pouch-Anal Anastomosis

(2013) Andrea D. Tyler et al.   PLoS One

Genome-wide mapping of gene–microbiota interactions in susceptibility to autoimmune skin blistering

(2013) Girish Srinivas et al.   Nature Communications

Estimating the Number of Species in Microbial Diversity Studies

(2013) John Bunge et al.   Annual Review of Statistics and Its Application

How Can Faecalibacterium prausnitzii Employ Riboflavin for Extracellular Electron Transfer?

(2012) M. Tanweer Khan et al.   ANTIOXIDANTS & REDOX SIGNALING

optiCall: a robust genotype-calling algorithm for rare, low-frequency and common variants

(2012) T. S. Shah et al.   BIOINFORMATICS

Gut microbiome composition is linked to whole grain-induced immunological improvements

(2012) Inés Martínez et al.   ISME Journal

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

(2012) Huai-Xiang Hao et al.   NATURE

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Improved whole-chromosome phasing for disease and population genetic studies

(2012) Olivier Delaneau et al.   NATURE METHODS

The influence of diet on the gut microbiota

(2012) Karen P. Scott et al.   PHARMACOLOGICAL RESEARCH

Murine Gut Microbiota Is Defined by Host Genetics and Modulates Variation of Metabolic Traits

(2012) Autumn M. McKnite et al.   PLoS One

Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

(2012) I. D. Iliev et al.   SCIENCE

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

(2012) Xochitl C Morgan et al.   GENOME BIOLOGY

Genetic adaptation of the antibacterial human innate immunity network

(2011) Ferran Casals et al.   BMC EVOLUTIONARY BIOLOGY

Self-reported energy intake by FFQ compared with actual energy intake to maintain body weight in 516 adults

(2011) Els Siebelink et al.   BRITISH JOURNAL OF NUTRITION

Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

(2011) R. J. Strawbridge et al.   DIABETES

A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3

(2011) Robert C. Kaplan et al.   HUMAN MOLECULAR GENETICS

The UniProt-GO Annotation database in 2011

(2011) E. C. Dimmer et al.   NUCLEIC ACIDS RESEARCH

Expression of KITENIN in human colorectal cancer and its relation to tumor behavior and progression

(2011) Seok Lee et al.   PATHOLOGY INTERNATIONAL

Genotype Imputation with Thousands of Genomes

(2011) Bryan Howie et al.   G3-Genes Genomes Genetics

DAP1, a Novel Substrate of mTOR, Negatively Regulates Autophagy

(2010) Itay Koren et al.   CURRENT BIOLOGY

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-wide association scans identified CTNNBL1 as a novel gene for obesity

(2008) Yong-Jun Liu et al.   HUMAN MOLECULAR GENETICS

Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall

(2008) Godfrey S. Getz et al.   JOURNAL OF LIPID RESEARCH