Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance
出版年份 2022 全文链接
标题
Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance
作者
关键词
-
出版物
NATURE CELL BIOLOGY
Volume 24, Issue 2, Pages 168-180
出版商
Springer Science and Business Media LLC
发表日期
2022-02-15
DOI
10.1038/s41556-022-00843-w
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mechanical Stiffness Controls Dendritic Cell Metabolism and Function
- (2021) Mainak Chakraborty et al. Cell Reports
- Actin cables and comet tails organize mitochondrial networks in mitosis
- (2021) Andrew S. Moore et al. NATURE
- Function and regulation of the divisome for mitochondrial fission
- (2021) Felix Kraus et al. NATURE
- Distinct fission signatures predict mitochondrial degradation or biogenesis
- (2021) Tatjana Kleele et al. NATURE
- Adhesion-mediated mechanosignaling forces mitohormesis
- (2021) Kevin M. Tharp et al. Cell Metabolism
- Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development
- (2021) Arianna Pocaterra et al. Communications Biology
- Applications and Approaches for 3D Precision-cut Lung Slices: Disease Modeling and Drug Discovery
- (2020) Hani N Alsafadi et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications
- (2020) Asish Dasgupta et al. FASEB JOURNAL
- Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination
- (2020) Marco Montagner et al. NATURE CELL BIOLOGY
- The cell biology of mitochondrial membrane dynamics
- (2020) Marta Giacomello et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanical Forces as Determinants of Disseminated Metastatic Cell Fate
- (2020) Marco Montagner et al. Cells
- In vitro Models of Breast Cancer Metastatic Dormancy
- (2020) Marco Montagner et al. Frontiers in Cell and Developmental Biology
- Lipid peroxidation and ferroptosis: The role of GSH and GPx4
- (2020) Fulvio Ursini et al. FREE RADICAL BIOLOGY AND MEDICINE
- Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
- (2020) Helmut Sies et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The NRF2/KEAP1 Axis in the Regulation of Tumor Metabolism: Mechanisms and Therapeutic Perspectives
- (2020) Emiliano Panieri et al. Biomolecules
- Intravital three-dimensional bioprinting
- (2020) Anna Urciuolo et al. Nature Biomedical Engineering
- Mechanical Adaptability of Tumor Cells in Metastasis
- (2020) Valentin Gensbittel et al. DEVELOPMENTAL CELL
- 3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis
- (2020) Nobuaki Takahashi et al. MOLECULAR CELL
- Heat stress activates YAP/TAZ to induce the heat shock transcriptome
- (2020) Min Luo et al. NATURE CELL BIOLOGY
- An expanded palette of improved SPLICS reporters detects multiple organelle contacts in vitro and in vivo
- (2020) Francesca Vallese et al. Nature Communications
- Translocating transcription factors in fluid shear stress-mediated vascular remodeling and disease
- (2019) Elizabeth Min et al. EXPERIMENTAL CELL RESEARCH
- Extracellular matrix mechanical cues regulate lipid metabolism through Lipin-1 and SREBP
- (2019) Patrizia Romani et al. NATURE CELL BIOLOGY
- F-actin dynamics regulates mammalian organ growth and cell fate maintenance
- (2019) Arianna Pocaterra et al. JOURNAL OF HEPATOLOGY
- Identification of a mechanogenetic link between substrate stiffness and chemotherapeutic response in breast cancer
- (2019) Scott H. Medina et al. BIOMATERIALS
- Materials Stiffness‐Dependent Redox Metabolic Reprogramming of Mesenchymal Stem Cells for Secretome‐Based Therapeutic Angiogenesis
- (2019) Haibo Yang et al. Advanced Healthcare Materials
- Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury
- (2019) Danchen Wu et al. FASEB JOURNAL
- Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture
- (2019) Giovanni Giuseppe Giobbe et al. Nature Communications
- NRF2 and the Hallmarks of Cancer
- (2018) Montserrat Rojo de la Vega et al. CANCER CELL
- Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension
- (2018) Kuang-Hueih Chen et al. CIRCULATION
- A polydnavirus-encoded ANK protein has a negative impact on steroidogenesis and development
- (2018) Marilena Ignesti et al. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Mechanosensing and fibrosis
- (2018) Daniel J. Tschumperlin et al. JOURNAL OF CLINICAL INVESTIGATION
- Caveolin-1 Controls Hyperresponsiveness to Mechanical Stimuli and Fibrogenesis-Associated RUNX2 Activation in Keloid Fibroblasts
- (2018) Chao-Kai Hsu et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells
- (2018) Mark A. Hawk et al. NATURE CELL BIOLOGY
- Mechanisms and impact of altered tumour mechanics
- (2018) Hamid Mohammadi et al. NATURE CELL BIOLOGY
- Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
- (2018) Laura Vera-Ramirez et al. Nature Communications
- Uncoupled mitochondria quickly shorten along their long axis to form indented spheroids, instead of rings, in a fission-independent manner
- (2018) Yoshihiro Miyazono et al. Scientific Reports
- Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy
- (2018) Thomas Bertero et al. Cell Metabolism
- Dormant tumour cells, their niches and the influence of immunity
- (2018) Erica T. Goddard et al. NATURE CELL BIOLOGY
- Metabolic shifts in residual breast cancer drive tumor recurrence
- (2017) Kristina M. Havas et al. JOURNAL OF CLINICAL INVESTIGATION
- Multiscale force sensing in development
- (2017) Nicoletta I. Petridou et al. NATURE CELL BIOLOGY
- Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis
- (2017) Rodrigo Romero et al. NATURE MEDICINE
- Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism
- (2017) Rongkun Tao et al. NATURE METHODS
- Global treadmilling coordinates actin turnover and controls the size of actin networks
- (2017) Marie-France Carlier et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanical forces direct stem cell behaviour in development and regeneration
- (2017) Kyle H. Vining et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanical force induces mitochondrial fission
- (2017) Sebastian Carsten Johannes Helle et al. eLife
- Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program
- (2016) Mireille Khacho et al. Cell Stem Cell
- The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease
- (2016) K. Atkins et al. CLINICAL SCIENCE
- Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model
- (2016) Sarah L Maguire et al. JOURNAL OF PATHOLOGY
- Early Evaluation of Relative Changes in Tumor Stiffness by Shear Wave Elastography Predicts the Response to Neoadjuvant Chemotherapy in Patients With Breast Cancer
- (2016) Hui Jing et al. JOURNAL OF ULTRASOUND IN MEDICINE
- Actin filaments as dynamic reservoirs for Drp1 recruitment
- (2016) Anna L. Hatch et al. MOLECULAR BIOLOGY OF THE CELL
- Reductive carboxylation supports redox homeostasis during anchorage-independent growth
- (2016) Lei Jiang et al. NATURE
- Internetwork competition for monomers governs actin cytoskeleton organization
- (2016) Cristian Suarez et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Dynamin controls extracellular level of Awd/Nme1 metastasis suppressor protein
- (2016) Patrizia Romani et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Dynamic actin cycling through mitochondrial subpopulations locally regulates the fission–fusion balance within mitochondrial networks
- (2016) Andrew S. Moore et al. Nature Communications
- Mitochondrial ROS Signaling in Organismal Homeostasis
- (2015) Gerald S. Shadel et al. CELL
- Evolution of Mitochondria as Signaling Organelles
- (2015) Navdeep S. Chandel Cell Metabolism
- Aerobic glycolysis tunes YAP/TAZ transcriptional activity
- (2015) E. Enzo et al. EMBO JOURNAL
- Inhibition of the autocrine IL-6–JAK2–STAT3–calprotectin axis as targeted therapy for HR−/HER2+breast cancers
- (2015) Ruth Rodriguez-Barrueco et al. GENES & DEVELOPMENT
- Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization
- (2015) Alexis J. Lomakin et al. NATURE CELL BIOLOGY
- Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state
- (2015) Fulvio Santacatterina et al. Oncotarget
- A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division
- (2015) Uri Manor et al. eLife
- Mitohormesis
- (2014) Jeanho Yun et al. Cell Metabolism
- Transient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fission
- (2014) Sunan Li et al. JOURNAL OF CELL BIOLOGY
- Mechanotransduction and extracellular matrix homeostasis
- (2014) Jay D. Humphrey et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Appreciating force and shape — the rise of mechanotransduction in cell biology
- (2014) Thomas Iskratsch et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
- (2014) John D. Hayes et al. TRENDS IN BIOCHEMICAL SCIENCES
- Preservation of micro-architecture and angiogenic potential in a pulmonary acellular matrix obtained using intermittent intra-tracheal flow of detergent enzymatic treatment
- (2013) Panagiotis Maghsoudlou et al. BIOMATERIALS
- An Integrin-Linked Machinery of Cytoskeletal Regulation that Enables Experimental Tumor Initiation and Metastatic Colonization
- (2013) Tsukasa Shibue et al. CANCER CELL
- Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission
- (2013) S. Koirala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2
- (2013) F. Korobova et al. SCIENCE
- HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers
- (2012) Marc L. Mendillo et al. CELL
- Fibroproliferative Disorders and Their Mechanobiology
- (2012) Chenyu Huang et al. CONNECTIVE TISSUE RESEARCH
- Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer
- (2012) Jalees Rehman et al. FASEB JOURNAL
- Arp2/3 complex–dependent actin networks constrain myosin II function in driving retrograde actin flow
- (2012) Qing Yang et al. JOURNAL OF CELL BIOLOGY
- Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles
- (2011) Abena S. Agyeman et al. BREAST CANCER RESEARCH AND TREATMENT
- Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia–reoxygenation stress
- (2011) X Liu et al. CELL DEATH AND DIFFERENTIATION
- 1-Integrin: A Potential Therapeutic Target in the Battle against Cancer Recurrence
- (2011) D. Barkan et al. CLINICAL CANCER RESEARCH
- MiD49 and MiD51, new components of the mitochondrial fission machinery
- (2011) Catherine S Palmer et al. EMBO REPORTS
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Metastatic Growth from Dormant Cells Induced by a Col-I-Enriched Fibrotic Environment
- (2010) D. Barkan et al. CANCER RESEARCH
- Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
- (2010) Fei Liu et al. JOURNAL OF CELL BIOLOGY
- Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
- (2009) Zachary T. Schafer et al. NATURE
- Inhibition of Metastatic Outgrowth from Single Dormant Tumor Cells by Targeting the Cytoskeleton
- (2008) D. Barkan et al. CANCER RESEARCH
- Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
- (2008) Ann Cassidy-Stone et al. DEVELOPMENTAL CELL
- Real-time imaging of the intracellular glutathione redox potential
- (2008) Marcus Gutscher et al. NATURE METHODS
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