Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization

Cortical Contractility Triggers a Stochastic Switch to Fast Amoeboid Cell Motility

(2015) Verena Ruprecht et al.   CELL

Confinement and Low Adhesion Induce Fast Amoeboid Migration of Slow Mesenchymal Cells

(2015) Yan-Jun Liu et al.   CELL

Actin Flows Mediate a Universal Coupling between Cell Speed and Cell Persistence

(2015) Paolo Maiuri et al.   CELL

Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways

(2015) Jeremy D. Rotty et al.   DEVELOPMENTAL CELL

Profilin Regulates F-Actin Network Homeostasis by Favoring Formin over Arp2/3 Complex

(2015) Cristian Suarez et al.   DEVELOPMENTAL CELL

Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase

(2015) Sunny S. Lou et al.   JOURNAL OF CELL BIOLOGY

Arp2/3 complex inhibition radically alters lamellipodial actin architecture, suspended cell shape, and the cell spreading process

(2015) John H. Henson et al.   MOLECULAR BIOLOGY OF THE CELL

Balance between cell−substrate adhesion and myosin contraction determines the frequency of motility initiation in fish keratocytes

(2015) Erin Barnhart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Homeostatic Actin Cytoskeleton Networks Are Regulated by Assembly Factor Competition for Monomers

(2014) Thomas A. Burke et al.   CURRENT BIOLOGY

Mesenchymal Chemotaxis Requires Selective Inactivation of Myosin II at the Leading Edge via a Noncanonical PLCγ/PKCα Pathway

(2014) Sreeja B. Asokan et al.   DEVELOPMENTAL CELL

Actin dynamics modulate mechanosensitive immobilization of E-cadherin at adherens junctions

(2014) W. Engl et al.   NATURE CELL BIOLOGY

Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia

(2014) Selwin K. Wu et al.   NATURE CELL BIOLOGY

Direct in Vivo RNAi Screen Unveils Myosin IIa as a Tumor Suppressor of Squamous Cell Carcinomas

(2014) D. Schramek et al.   SCIENCE

Competitive displacement of cofilin can promote actin filament severing

(2013) W. Austin Elam et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin

(2013) Stefan A. Koestler et al.   MOLECULAR BIOLOGY OF THE CELL

Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells

(2013) M. A. Nieto   SCIENCE

ADF/Cofilin Regulates Actomyosin Assembly through Competitive Inhibition of Myosin II Binding to F-Actin

(2012) O'Neil Wiggan et al.   DEVELOPMENTAL CELL

Functions of Nonmuscle Myosin II in Assembly of the Cellular Contractile System

(2012) Maria Shutova et al.   PLoS One

Cofilin under control of  -arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learning

(2012) C. G. Pontrello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Polarity as a Regulator of Cancer Cell Behavior Plasticity

(2011) Senthil K. Muthuswamy et al.   Annual Review of Cell and Developmental Biology

Analysis of the role of Ser1/Ser2/Thr9 phosphorylation on myosin II assembly and function in live cells

(2011) Jordan R Beach et al.   BMC CELL BIOLOGY

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

(2011) Kimihide Hayakawa et al.   JOURNAL OF CELL BIOLOGY

A pharmacological cocktail for arresting actin dynamics in living cells

(2011) Grace E. Peng et al.   MOLECULAR BIOLOGY OF THE CELL

Visualizing branched actin filaments in lamellipodia by electron tomography

(2011) Changsong Yang et al.   NATURE CELL BIOLOGY

Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows

(2010) Mirjam Mayer et al.   NATURE

Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

(2010) John T. Connelly et al.   NATURE CELL BIOLOGY

Dendritic Actin Filament Nucleation Causes Traveling Waves and Patches

(2010) Anders E. Carlsson   PHYSICAL REVIEW LETTERS

Mechanical modes of ‘amoeboid’ cell migration

(2009) Tim Lämmermann et al.   CURRENT OPINION IN CELL BIOLOGY

Phospholipase C–mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane

(2009) Jian-Jiang Hao et al.   JOURNAL OF CELL BIOLOGY

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulating the Conversion between Rounded and Elongated Modes of Cancer Cell Movement

(2008) Daniel R. Croft et al.   CANCER CELL

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

ACF7 Regulates Cytoskeletal-Focal Adhesion Dynamics and Migration and Has ATPase Activity

(2008) Xiaoyang Wu et al.   CELL

Rho-Kinase Phosphorylates PAR-3 and Disrupts PAR Complex Formation

(2008) Masanori Nakayama et al.   DEVELOPMENTAL CELL

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY