Cell cycle involvement in cancer therapy; WEE1 kinase, a potential target as therapeutic strategy
出版年份 2022 全文链接
标题
Cell cycle involvement in cancer therapy; WEE1 kinase, a potential target as therapeutic strategy
作者
关键词
Cell cycle, WEE1 kinase, Cancer, DNA damage, Checkpoint
出版物
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Volume -, Issue -, Pages 111776
出版商
Elsevier BV
发表日期
2022-02-19
DOI
10.1016/j.mrfmmm.2022.111776
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Inhibiting Wee1 and ATR kinases produces tumor-selective synthetic lethality and suppresses metastasis
- (2019) Amirali B. Bukhari et al. JOURNAL OF CLINICAL INVESTIGATION
- Antileukemic activity and mechanism of action of the novel PI3K and histone deacetylase dual inhibitor CUDC-907 in acute myeloid leukemia
- (2019) Xinyu Li et al. HAEMATOLOGICA
- Allosteric Regulation of Cyclin-B Binding by the Charge State of Catalytic Lysine in CDK1 Is Essential for Cell-Cycle Progression
- (2019) Shaunak Deota et al. JOURNAL OF MOLECULAR BIOLOGY
- Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation
- (2019) Maksym Tsytlonok et al. Nature Communications
- Inhibition of Wee1 sensitizes AML cells to ATR inhibitor VE-822-induced DNA damage and apoptosis
- (2019) Wenxiu Qi et al. BIOCHEMICAL PHARMACOLOGY
- Orchestration of the spindle assembly checkpoint by CDK1‐cyclin B1
- (2019) Daniel Hayward et al. FEBS LETTERS
- CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle
- (2019) Grzegorz Sarek et al. NATURE
- Anti-Tumor Effects of Wee1 Kinase Inhibitor with Radiotherapy in Human Cervical Cancer
- (2019) Yoo-Young Lee et al. Scientific Reports
- Identification of a rhodium(iii) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells
- (2018) Guan-Jun Yang et al. CHEMICAL COMMUNICATIONS
- Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non–Small Cell Lung Cancer
- (2018) Chellappagounder Thangavel et al. CLINICAL CANCER RESEARCH
- Cyclin A-cdk1-Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry
- (2018) Suzanne Vigneron et al. DEVELOPMENTAL CELL
- Multiple functions of p27 in cell cycle, apoptosis, epigenetic modification and transcriptional regulation for the control of cell growth: A double-edged sword protein
- (2018) Maryam Abbastabar et al. DNA REPAIR
- Combined Inhibition of ATR and WEE1 as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer
- (2018) Juan Jin et al. NEOPLASIA
- Persistent repair intermediates induce senescence
- (2018) F. M. Feringa et al. Nature Communications
- Cyclin-dependent protein serine/threonine kinase inhibitors as anticancer drugs
- (2018) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress
- (2018) Quentin Bayard et al. Nature Communications
- Identification, expression pattern and functional characterization of As-kip2 in diapause embryo restarting process of Artemia sinica
- (2017) Mengchen Zhang et al. GENE
- CDK4 protein is degraded by anaphase-promoting complex/cyclosome in mitosis and reaccumulates in early G1phase to initiate a new cell cycle in HeLa cells
- (2017) Huabo Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of repair pathway choice at two-ended DNA double-strand breaks
- (2017) Atsushi Shibata MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma
- (2017) Shaofang Wu et al. NEURO-ONCOLOGY
- JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21
- (2017) B Colleoni et al. ONCOGENE
- Control of oocyte meiotic maturation in C. elegans
- (2017) Gabriela Huelgas-Morales et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis
- (2017) Atsushi Okuma et al. Nature Communications
- Tributylphosphate (TBP) and tris (2-butoxyethyl) phosphate (TBEP) induced apoptosis and cell cycle arrest in HepG2 cells
- (2017) Guofa Ren et al. Toxicology Research
- The G2 checkpoint-a node-based molecular switch
- (2017) Mark C. de Gooijer et al. FEBS Open Bio
- Orchestration of DNA Damage Checkpoint Dynamics across the Human Cell Cycle
- (2017) Hui Xiao Chao et al. Cell Systems
- WEE1 inhibition targets cell cycle checkpoints for triple negative breast cancers to overcome cisplatin resistance
- (2017) Hongping Zheng et al. Scientific Reports
- A Strategy for Direct Chemical Activation of the Retinoblastoma Protein
- (2016) Cameron R. Pye et al. ACS Chemical Biology
- Small-Molecule PROTACS: New Approaches to Protein Degradation
- (2016) Momar Toure et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Targeting CDK4/6 in patients with cancer
- (2016) Erika Hamilton et al. CANCER TREATMENT REVIEWS
- Irreversible APC Cdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry
- (2016) Steven D. Cappell et al. CELL
- Cyclin D1, cancer progression, and opportunities in cancer treatment
- (2016) Shuo Qie et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Molecular mechanism of APC/C activation by mitotic phosphorylation
- (2016) Suyang Zhang et al. NATURE
- Molecular basis of APC/C regulation by the spindle assembly checkpoint
- (2016) Claudio Alfieri et al. NATURE
- Targeting the RB-E2F pathway in breast cancer
- (2016) J Johnson et al. ONCOGENE
- Cyclin-dependent protein kinase inhibitors including palbociclib as anticancer drugs
- (2016) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Cyclin-dependent kinase 1-dependent activation of APC/C ubiquitin ligase
- (2016) K. Fujimitsu et al. SCIENCE
- Targeting WEE1 Kinase in Cancer
- (2016) Christopher J. Matheson et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Interphase APC/C–Cdc20 inhibition by cyclin A2–Cdk2 ensures efficient mitotic entry
- (2016) Jamin B. Hein et al. Nature Communications
- Long non-coding RNA ANRIL promotes the invasion and metastasis of thyroid cancer cells through TGF-β/Smad signaling pathway
- (2016) Jian-Jie Zhao et al. Oncotarget
- A Dynamical Framework for the All-or-None G1/S Transition
- (2016) Alexis R. Barr et al. Cell Systems
- Regulation of the retinoblastoma–E2F pathway by the ubiquitin–proteasome system
- (2015) Satyaki Sengupta et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Conformational Equilibrium of CDK/Cyclin Complexes by Molecular Dynamics with Excited Normal Modes
- (2015) Nicolas Floquet et al. BIOPHYSICAL JOURNAL
- Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma
- (2015) Gry Irene Magnussen et al. BMC CANCER
- A role for homologous recombination proteins in cell cycle regulation
- (2015) Kaja Kostyrko et al. CELL CYCLE
- CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma
- (2015) M. E. Olanich et al. CLINICAL CANCER RESEARCH
- DNA damage checkpoint recovery and cancer development
- (2015) Haiyong Wang et al. EXPERIMENTAL CELL RESEARCH
- Model scenarios for switch-like mitotic transitions
- (2015) P.K. Vinod et al. FEBS LETTERS
- p16INK4A inhibits the pro-metastatic potentials of osteosarcoma cells through targeting the ERK pathway and TGF-β1
- (2015) Gabriela Silva et al. MOLECULAR CARCINOGENESIS
- Age dynamics of DNA damage and CpG methylation in the peripheral blood leukocytes of mice
- (2015) Ilya Velegzhaninov et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Phthalimide conjugation as a strategy for in vivo target protein degradation
- (2015) G. E. Winter et al. SCIENCE
- Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells
- (2015) Joyce P.Y. Mak et al. Oncotarget
- Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair
- (2015) Tasneem Kausar et al. NEOPLASIA
- Two Distinct Cdc2 Pools Regulate Cell Cycle Progression and the DNA Damage Response in the Fission Yeast S.pombe
- (2015) Thomas Caspari et al. PLoS One
- CDK inhibitors, p21Cip1 and p27Kip1, participate in cell cycle exit of mammalian cardiomyocytes
- (2014) Shoji Tane et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cdk1 Inactivation Terminates Mitotic Checkpoint Surveillance and Stabilizes Kinetochore Attachments in Anaphase
- (2014) María Dolores Vázquez-Novelle et al. CURRENT BIOLOGY
- PP2A delays APC/C-dependent degradation of separase-associated but not free securin
- (2014) S. Hellmuth et al. EMBO JOURNAL
- The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C
- (2014) Daisuke Izawa et al. NATURE
- A PP1–PP2A phosphatase relay controls mitotic progression
- (2014) Agnes Grallert et al. NATURE
- DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response
- (2014) Yu-Fen Lin et al. NUCLEIC ACIDS RESEARCH
- DNA damage checkpoints in nasopharyngeal carcinoma
- (2014) Randy Y.C. Poon ORAL ONCOLOGY
- ATR Suppresses Endogenous DNA Damage and Allows Completion of Homologous Recombination Repair
- (2014) Adam D. Brown et al. PLoS One
- A Data-Driven, Mathematical Model of Mammalian Cell Cycle Regulation
- (2014) Michael C. Weis et al. PLoS One
- Androgen Suppresses the Proliferation of Androgen Receptor-Positive Castration-Resistant Prostate Cancer Cells via Inhibition of Cdk2, CyclinA, and Skp2
- (2014) John M. Kokontis et al. PLoS One
- Changes in Oscillatory Dynamics in the Cell Cycle of Early Xenopus laevis Embryos
- (2014) Tony Y.-C. Tsai et al. PLOS BIOLOGY
- Cyclin-dependent kinases
- (2014) Marcos Malumbres GENOME BIOLOGY
- Mechanisms for Initiating Cellular DNA Replication
- (2013) Alessandro Costa et al. Annual Review of Biochemistry
- The ubiquitin proteasome system — Implications for cell cycle control and the targeted treatment of cancer
- (2013) Florian Bassermann et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Identification of the lamin A/C phosphoepitope recognized by the antibody P-STM in mitotic HeLa S3 cells
- (2013) Jeng-Ting Chen et al. BMC BIOCHEMISTRY
- New Structural Insights into Phosphorylation-free Mechanism for Full Cyclin-dependent Kinase (CDK)-Cyclin Activity and Substrate Recognition
- (2013) Fei Zheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Cdk1–APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch
- (2013) Qiong Yang et al. NATURE CELL BIOLOGY
- Control of cell cycle transcription during G1 and S phases
- (2013) Cosetta Bertoli et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Multisite phosphorylation networks as signal processors for Cdk1
- (2013) Mardo Kõivomägi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Phosphoinositide-3-kinases p110α and p110β mediate S phase entry in astroglial cells in the marginal zone of rat neocortex
- (2013) Rabea Müller et al. Frontiers in Cellular Neuroscience
- Signaling Pathways that Control Cell Proliferation
- (2013) R. J. Duronio et al. Cold Spring Harbor Perspectives in Biology
- Cisplatin Sensitivity Mediated by WEE1 and CHK1 Is Mediated by miR-155 and the miR-15 Family
- (2012) L. M. Pouliot et al. CANCER RESEARCH
- Separase Sensor Reveals Dual Roles for Separase Coordinating Cohesin Cleavage and Cdk1 Inhibition
- (2012) Norihisa Shindo et al. DEVELOPMENTAL CELL
- Sensor and effector kinases in DNA damage checkpoint regulate capacity for homologous recombination repair of fission yeast in G2 phase
- (2012) Shinji Yasuhira et al. DNA REPAIR
- Effect of positive feedback loops on the robustness of oscillations in the network of cyclin-dependent kinases driving the mammalian cell cycle
- (2012) Claude Gérard et al. FEBS Journal
- Modification of the DNA Damage Response by Therapeutic CDK4/6 Inhibition
- (2012) Jeffry L. Dean et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control
- (2012) A. Mocciaro et al. JOURNAL OF CELL SCIENCE
- Forced Mitotic Entry of S-Phase Cells as a Therapeutic Strategy Induced by Inhibition of WEE1
- (2012) Marieke Aarts et al. Cancer Discovery
- Phosphorylation of Nup98 by Multiple Kinases Is Crucial for NPC Disassembly during Mitotic Entry
- (2011) Eva Laurell et al. CELL
- Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
- (2011) L Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Eukaryotic DNA damage checkpoint activation in response to double-strand breaks
- (2011) Karen Finn et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cdc14 Phosphatases Preferentially Dephosphorylate a Subset of Cyclin-dependent kinase (Cdk) Sites Containing Phosphoserine
- (2011) Steven C. Bremmer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation
- (2011) Jun-Song Chen et al. JOURNAL OF CELL BIOLOGY
- Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
- (2011) M. Cargnello et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Stress-Stimulated Mitogen-Activated Protein Kinases Control the Stability and Activity of the Cdt1 DNA Replication Licensing Factor
- (2011) S. Chandrasekaran et al. MOLECULAR AND CELLULAR BIOLOGY
- Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited
- (2011) Tamara A. Potapova et al. MOLECULAR BIOLOGY OF THE CELL
- Coupling of T161 and T14 phosphorylations protects cyclin B–CDK1 from premature activation
- (2011) Katia Coulonval et al. MOLECULAR BIOLOGY OF THE CELL
- Temporal control of nuclear envelope assembly by phosphorylation of lamin B receptor
- (2011) Li-Chuan Tseng et al. MOLECULAR BIOLOGY OF THE CELL
- Ultrasensitivity and Positive Feedback to Promote Sharp Mitotic Entry
- (2011) Youlian Goulev et al. MOLECULAR CELL
- Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication
- (2011) C. S. Sorensen et al. NUCLEIC ACIDS RESEARCH
- Switches and latches: a biochemical tug-of-war between the kinases and phosphatases that control mitosis
- (2011) M. R. Domingo-Sananes et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Rising Cyclin-CDK Levels Order Cell Cycle Events
- (2011) Catherine Oikonomou et al. PLoS One
- Cyclin A2 Mutagenesis Analysis: A New Insight into CDK Activation and Cellular Localization Requirements
- (2011) Nawal Bendris et al. PLoS One
- Coordinate regulation of histone mRNA metabolism and DNA replication
- (2010) M. Murat Koseoglu et al. CELL CYCLE
- Centrosomal Localization of Cyclin E-Cdk2 Is Required for Initiation of DNA Synthesis
- (2010) Rebecca L. Ferguson et al. CURRENT BIOLOGY
- Cdc25 Phosphatases Are Required for Timely Assembly of CDK1-Cyclin B at the G2/M Transition
- (2010) Oleg Timofeev et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Quantitative Reconstitution of Mitotic CDK1 Activation in Somatic Cell Extracts
- (2010) Richard W. Deibler et al. MOLECULAR CELL
- Driving the cell cycle with a minimal CDK control network
- (2010) Damien Coudreuse et al. NATURE
- Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei
- (2010) Raquel A. Oliveira et al. NATURE CELL BIOLOGY
- Dissociation of CAK from Core TFIIH Reveals a Functional Link between XP-G/CS and the TFIIH Disassembly State
- (2010) Hany H. Arab et al. PLoS One
- Modulation of the Biological Properties of Aspirin by Formation of a Bioorganometallic Derivative
- (2009) Ingo Ott et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Centrosome-associated regulators of the G2/M checkpoint as targets for cancer therapy
- (2009) Yingmei Wang et al. Molecular Cancer
- A quantitative atlas of mitotic phosphorylation
- (2008) N. Dephoure et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started