标题
The acid sphingomyelinase/ceramide system in COVID-19
作者
关键词
-
出版物
MOLECULAR PSYCHIATRY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-10-05
DOI
10.1038/s41380-021-01309-5
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Dexamethasone use and mortality in hospitalized patients with coronavirus disease 2019: A multicentre retrospective observational study
- (2021) Nicolas Hoertel et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Association between antidepressant use and reduced risk of intubation or death in hospitalized patients with COVID-19: results from an observational study
- (2021) Nicolas Hoertel et al. MOLECULAR PSYCHIATRY
- Prospective Cohort of Fluvoxamine for Early Treatment of Coronavirus Disease 19
- (2021) David Seftel et al. Open Forum Infectious Diseases
- Fluoxetine Can Inhibit SARS-CoV-2 In Vitro
- (2021) Arthur Dechaumes et al. Microorganisms
- Association between Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) and Reduced Risk of Death in COVID-19 Patients: A Retrospective Cohort Study
- (2021) Gil Darquennes et al. Pharmaceuticals
- Drug synergy of combinatory treatment with remdesivir and the repurposed drugs fluoxetine and itraconazole effectively impairs SARS‐CoV‐2 infection in vitro
- (2021) Sebastian Schloer et al. BRITISH JOURNAL OF PHARMACOLOGY
- Metabolic Signatures Associated with Severity in Hospitalized COVID-19 Patients
- (2021) Judith Marín-Corral et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Clofazimine broadly inhibits coronaviruses including SARS-CoV-2
- (2021) Shuofeng Yuan et al. NATURE
- Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials
- (2021) Cathrine Axfors et al. Nature Communications
- The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 in human lung tissue
- (2021) Melissa Zimniak et al. Scientific Reports
- SARS-CoV-2 infection induces the activation of tissue factor–mediated coagulation via activation of acid sphingomyelinase
- (2021) Jue Wang et al. BLOOD
- Association Between FIASMAs and Reduced Risk of Intubation or Death in Individuals Hospitalized for Severe COVID‐19: An Observational Multicenter Study
- (2021) Nicolas Hoertel et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Repurposing antidepressants inhibiting the sphingomyelinase acid/ceramide system against COVID-19: current evidence and potential mechanisms
- (2021) Nicolas Hoertel et al. MOLECULAR PSYCHIATRY
- Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19
- (2021) Carmen Mirabelli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of drugs associated with reduced severity of COVID-19 – a case-control study in a large population
- (2021) Ariel Israel et al. eLife
- Fusion of lysosomes to plasma membrane initiates radiation-induced apoptosis
- (2020) Charles S. Ferranti et al. JOURNAL OF CELL BIOLOGY
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study
- (2020) Xiaobo Yang et al. Lancet Respiratory Medicine
- Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs
- (2020) Sangeun Jeon et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
- (2020) Qihui Wang et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
- (2020) Jun Lan et al. NATURE
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- Artificial intelligence approach fighting COVID-19 with repurposing drugs
- (2020) Yi-Yu Ke et al. Biomedical Journal
- Repurposing old drugs as antiviral agents for coronaviruses
- (2020) Cheng-Wei Yang et al. Biomedical Journal
- Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro
- (2020) Ka-Tim Choy et al. ANTIVIRAL RESEARCH
- Comorbidities and the risk of severe or fatal outcomes associated with coronavirus disease 2019: A systematic review and meta-analysis
- (2020) Yue Zhou et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Estimates of the severity of coronavirus disease 2019: a model-based analysis
- (2020) Robert Verity et al. LANCET INFECTIOUS DISEASES
- A stochastic agent-based model of the SARS-CoV-2 epidemic in France
- (2020) Nicolas Hoertel et al. NATURE MEDICINE
- Repurposing Therapeutics for Potential Treatment of SARS-CoV-2: A Review
- (2020) Jennifer Santos et al. Viruses-Basel
- In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication
- (2020) Franck Touret et al. Scientific Reports
- Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19
- (2020) et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Broad Anti-coronavirus Activity of Food and Drug Administration-Approved Drugs against SARS-CoV-2 In Vitro and SARS-CoV In Vivo
- (2020) Stuart Weston et al. JOURNAL OF VIROLOGY
- Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
- (2020) David E. Gordon et al. SCIENCE
- Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19
- (2020) Eric J. Lenze et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis
- (2020) Imad M. Tleyjeh et al. CLINICAL MICROBIOLOGY AND INFECTION
- Elevated plasma ceramide levels in post-menopausal women: a cross-sectional study
- (2019) Valentina Vozella et al. Aging-US
- Modulation of the sigma-1 receptor–IRE1 pathway is beneficial in preclinical models of inflammation and sepsis
- (2019) Dorian A. Rosen et al. Science Translational Medicine
- Acid sphingomyelinase plays a critical role in LPS- and cytokine-induced tissue factor procoagulant activity
- (2019) Jue Wang et al. BLOOD
- Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration
- (2018) Timothy A. Couttas et al. JOURNAL OF ALZHEIMERS DISEASE
- Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
- (2018) Min Hee Park et al. NEURON
- Drug repurposing: progress, challenges and recommendations
- (2018) Sudeep Pushpakom et al. NATURE REVIEWS DRUG DISCOVERY
- Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver
- (2017) Ha-Yeun Chung et al. Scientific Reports
- Secretory sphingomyelinase in health and disease
- (2015) Johannes Kornhuber et al. BIOLOGICAL CHEMISTRY
- Regulation of hematogenous tumor metastasis by acid sphingomyelinase
- (2015) A. Carpinteiro et al. EMBO Molecular Medicine
- Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis
- (2015) Huiming Peng et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Ceramide formation mediated by acid sphingomyelinase facilitates endosomal escape of caliciviruses
- (2015) Vinay Shivanna et al. VIROLOGY
- Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture
- (2014) Adriaan H. de Wilde et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Testing of Middle East Respiratory Syndrome Coronavirus Replication Inhibitors for the Ability To Block Viral Entry
- (2014) Qi Liu et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection
- (2014) Julie Dyall et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Interaction of new antidepressants with sigma-1 receptor chaperones and their potentiation of neurite outgrowth in PC12 cells
- (2014) Tamaki Ishima et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Defining a Role for Acid Sphingomyelinase in the p38/Interleukin-6 Pathway
- (2014) David M. Perry et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dose-Dependent Effects of Rosuvastatin on the Plasma Sphingolipidome and Phospholipidome in the Metabolic Syndrome
- (2014) Theodore W. K. Ng et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor
- (2014) T Omi et al. Cell Death & Disease
- Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study
- (2013) Lutz Nährlich et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Anti-ceramide antibody prevents the radiation gastrointestinal syndrome in mice
- (2012) Jimmy Rotolo et al. JOURNAL OF CLINICAL INVESTIGATION
- Ebolavirus Requires Acid Sphingomyelinase Activity and Plasma Membrane Sphingomyelin for Infection
- (2012) M. E. Miller et al. JOURNAL OF VIROLOGY
- Identification of Novel Functional Inhibitors of Acid Sphingomyelinase
- (2011) Johannes Kornhuber et al. PLoS One
- Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide
- (2011) Léon J. A. Spijkers et al. PLoS One
- DC-SIGN Mediated Sphingomyelinase-Activation and Ceramide Generation Is Essential for Enhancement of Viral Uptake in Dendritic Cells
- (2011) Elita Avota et al. PLoS Pathogens
- Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): A Novel Pharmacological Group of Drugs with Broad Clinical Applications
- (2010) Johannes Kornhuber et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Role of Sphingolipid Mediator Ceramide in Obesity and Renal Injury in Mice Fed a High-Fat Diet
- (2010) K. M. Boini et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Efficient Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by the Transmembrane Protease TMPRSS2
- (2010) S. Matsuyama et al. JOURNAL OF VIROLOGY
- Involvement of Ceramide in the Propagation of Japanese Encephalitis Virus
- (2010) H. Tani et al. JOURNAL OF VIROLOGY
- Therapeutic Efficacy and Safety of Amitriptyline in Patients with Cystic Fibrosis
- (2009) Joachim Riethmüller et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Pharmacology and Therapeutic Potential of Sigma1 Receptor Ligands
- (2009) E. Cobos et al. Current Neuropharmacology
- Quantitative modeling of selective lysosomal targeting for drug design
- (2008) Stefan Trapp et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis
- (2008) Volker Teichgräber et al. NATURE MEDICINE
- Identification of New Functional Inhibitors of Acid Sphingomyelinase Using a Structure−Property−Activity Relation Model
- (2007) Johannes Kornhuber et al. JOURNAL OF MEDICINAL CHEMISTRY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started