Inflammasome regulation by adaptor isoforms, ASC and ASCb, via differential self-assembly

Structure, Activation and Regulation of NLRP3 and AIM2 Inflammasomes

(2021) Meenakshi Sharma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nuclear Receptors in the Control of the NLRP3 Inflammasome Pathway

(2021) Hélène Duez et al.   Frontiers in Endocrinology

The Roles of the NLRP3 Inflammasome in Neurodegenerative and Metabolic Diseases and in Relevant Advanced Therapeutic Interventions

(2020) Rameez Hassan Pirzada et al.   Genes

Kinetic diversity of amyloid oligomers

(2020) Alexander J. Dear et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia

(2020) Lea L. Friker et al.   Cell Reports

UCSF ChimeraX : Structure visualization for researchers, educators, and developers

(2020) Eric F. Pettersen et al.   PROTEIN SCIENCE

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

(2019) Nathan Kelley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Single-Molecule Fluorescence Reveals the Oligomerization and Folding Steps Driving the Prion-like Behavior of ASC

(2018) Yann Gambin et al.   JOURNAL OF MOLECULAR BIOLOGY

SUMO-mediated regulation of NLRP3 modulates inflammasome activity

(2018) Rachael Barry et al.   Nature Communications

The inflammasome adapter ASC assembles into filaments with integral participation of its two Death Domains, PYD and CARD

(2018) Reinard Jeffrey T. Nambayan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammasome activation and assembly at a glance

(2017) Ankit Malik et al.   JOURNAL OF CELL SCIENCE

Salt-Mediated Oligomerization of the Mouse Prion Protein Monitored by Real-Time NMR

(2017) Ishita Sengupta et al.   JOURNAL OF MOLECULAR BIOLOGY

Scaling behaviour and rate-determining steps in filamentous self-assembly

(2017) Georg Meisl et al.   Chemical Science

ASC Pyrin Domain Self-associates and Binds NLRP3 Protein Using Equivalent Binding Interfaces

(2016) Javier Oroz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation

(2016) Deepika Sharma et al.   JOURNAL OF CELL BIOLOGY

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes

(2016) G.C.P. van Zundert et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism

(2016) Alvin Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism

(2016) Alvin Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of inflammasome activation

(2015) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Initiation and perpetuation of NLRP3 inflammasome activation and assembly

(2015) Eric I. Elliott et al.   IMMUNOLOGICAL REVIEWS

Activation and assembly of the inflammasomes through conserved protein domain families

(2014) Tengchuan Jin et al.   APOPTOSIS

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex

(2014) S. M. Man et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using chemical shift perturbation to characterise ligand binding

(2013) Mike P. Williamson   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Helical assembly in the death domain (DD) superfamily

(2012) Ryan Ferrao et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes

(2010) Nicole B Bryan et al.   Journal of Inflammation-London

Kinetics of Amyloid β Monomer-to-Oligomer Exchange by NMR Relaxation

(2010) Nicolas L. Fawzi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

Structure and Interdomain Dynamics of Apoptosis-associated Speck-like Protein Containing a CARD (ASC)

(2009) Eva de Alba   JOURNAL OF BIOLOGICAL CHEMISTRY

A Splice Variant of ASC Regulates IL-1βRelease and Aggregates Differently from Intact ASC

(2009) Kazuhiko Matsushita et al.   MEDIATORS OF INFLAMMATION

Protein aggregation kinetics, mechanism, and curve-fitting: A review of the literature

(2008) Aimee M. Morris et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS