Dioscin alleviates lung ischemia/reperfusion injury by regulating FXR-mediated oxidative stress, apoptosis, and inflammation

Oxidative stress and mitochondrial dysfunction mediated Cd-induced hepatic lipid accumulation in zebrafish Danio rerio

(2018) Ya-Xiong Pan et al.   AQUATIC TOXICOLOGY

Beneficial effects of bile acid receptor agonists in pulmonary disease models

(2017) Paolo Comeglio et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Daphnetin-mediated Nrf2 antioxidant signaling pathways ameliorate tert-butyl hydroperoxide ( t -BHP)-induced mitochondrial dysfunction and cell death

(2017) Hongming Lv et al.   FREE RADICAL BIOLOGY AND MEDICINE

1α,25-Dihydroxyvitamin D3 Ameliorates Seawater Aspiration-Induced Lung Injury By Inhibiting The Translocation Of NF-κB and RhoA

(2017) Minlong Zhang et al.   INFLAMMATION

Cardiopulmonary protective effects of the selective FXR agonist obeticholic acid in the rat model of monocrotaline-induced pulmonary hypertension

(2017) Linda Vignozzi et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Inhibition of Na-K-Cl cotransporter isoform 1 reduces lung injury induced by ischemia–reperfusion

(2017) Chou-Chin Lan et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Farnesoid X Receptor Activation Attenuates Intestinal Ischemia Reperfusion Injury in Rats

(2017) Laurens J. Ceulemans et al.   PLoS One

Activation of the Nuclear Receptor Fxr Improves Intestinal Cell Tolerance to Ischemia–reperfusion Injury

(2017) Xuan Wang et al.   SHOCK

Inhibition of nuclear factor-κB signal by pyrrolidine dithiocarbamate alleviates lipopolysaccharide-induced acute lung injury

(2017) Hongfu Yang et al.   Oncotarget

Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation

(2017) Hong Yao et al.   Frontiers in Pharmacology

Adipose Gene Expression Profile Changes With Lung Allograft Reperfusion

(2016) J. M. Diamond et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Attenuation of Pulmonary Ischemia-Reperfusion Injury by Adenosine A 2B Receptor Antagonism

(2016) Mary E. Huerter et al.   ANNALS OF THORACIC SURGERY

Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats

(2016) Huifen Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition

(2016) Yupeng Hu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Alda-1 Attenuates Lung Ischemia-Reperfusion Injury by Reducing 4-Hydroxy-2-Nonenal in Alveolar Epithelial Cells

(2016) Jie Ding et al.   CRITICAL CARE MEDICINE

Role of NRF2 in MiR-181c/AMP-Activated Protein Kinase Signaling in Cancer

(2016) Kyeong-Ah Jung et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human α1-antitrypsin improves early post-transplant lung function: Pre-clinical studies in a pig lung transplant model

(2016) Ilker Iskender et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Beneficial effect of low-level laser therapy in acute lung injury after i-I/R is dependent on the secretion of IL-10 and independent of the TLR/MyD88 signaling

(2016) J. L. Carvalho et al.   LASERS IN MEDICAL SCIENCE

Nrf2—a Promising Therapeutic Target for Defensing Against Oxidative Stress in Stroke

(2016) Rongrong Zhang et al.   MOLECULAR NEUROBIOLOGY

EspC, an Autotransporter Protein Secreted by Enteropathogenic Escherichia coli , Causes Apoptosis and Necrosis through Caspase and Calpain Activation, Including Direct Procaspase-3 Cleavage

(2016) Antonio Serapio-Palacios et al.   mBio

Overexpression of farnesoid X receptor in small airways contributes to epithelial to mesenchymal transition and COX-2 expression in chronic obstructive pulmonary disease

(2016) Bi Chen et al.   Journal of Thoracic Disease

Curcumin protects ANIT-induced cholestasis through signaling pathway of FXR-regulated bile acid and inflammation

(2016) Fan Yang et al.   Scientific Reports

AMPK activation by liquiritigenin inhibited oxidative hepatic injury and mitochondrial dysfunction induced by nutrition deprivation as mediated with induction of farnesoid X receptor

(2015) Eun Hye Jung et al.   EUROPEAN JOURNAL OF NUTRITION

Dioscin ameliorates cerebral ischemia/reperfusion injury through the downregulation of TLR4 signaling via HMGB-1 inhibition

(2015) Xufeng Tao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Silver nanowire interactions with primary human alveolar type-II epithelial cell secretions: contrasting bioreactivity with human alveolar type-I and type-II epithelial cells

(2015) Sinbad Sweeney et al.   Nanoscale

Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70

(2015) Meng Qi et al.   PHARMACOLOGICAL RESEARCH

CYP2J2 and EETs Protect against Oxidative Stress and Apoptosisin Vivoandin VitroFollowing Lung Ischemia/Reperfusion

(2014) Wenshu Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Relaxin protects against ischemia-reperfusion injury in rat lungs: role of ERK-1/2 and PI3 kinase

(2014) T. Dschietzig et al.   EUROPEAN HEART JOURNAL

Liver Kinase B1 Suppresses Lipopolysaccharide-induced Nuclear Factor κB (NF-κB) Activation in Macrophages

(2014) Zhaoyu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dioscin Attenuates Hepatic Ischemia-Reperfusion Injury in Rats Through Inhibition of Oxidative-Nitrative Stress, Inflammation and Apoptosis

(2014) Xufeng Tao et al.   TRANSPLANTATION

Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury

(2012) Jun Pu et al.   EUROPEAN HEART JOURNAL

FXR Protects Lung from Lipopolysaccharide-Induced Acute Injury

(2011) Lisheng Zhang et al.   MOLECULAR ENDOCRINOLOGY

Mitochondrial genome depletion dysregulates bile acid- and paracetamol-induced expression of the transporters Mdr1, Mrp1 and Mrp4 in liver cells

(2010) MJ Perez et al.   BRITISH JOURNAL OF PHARMACOLOGY

Anti-thrombotic activity and chemical characterization of steroidal saponins from Dioscorea zingiberensis C.H. Wright

(2010) Hua Li et al.   FITOTERAPIA

Application of Proteomic and Bioinformatic Techniques for Studying the Hepatoprotective Effect of Dioscin against CCl4-induced Liver Damage in Mice

(2010) Binan Lu et al.   PLANTA MEDICA

S81 Primary type II alveolar epithelial cells respond differentially to bacterial virulence factors

(2010) O. L. M. Nieto et al.   THORAX

Cytomegalovirus β2.7 RNA transcript protects endothelial cells against apoptosis during ischemia/reperfusion injury

(2009) Jing Zhao et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Spectral Monitoring of Surfactant Clearance during Alveolar Epithelial Type II Cell Differentiation

(2008) Robin J. Swain et al.   BIOPHYSICAL JOURNAL

FXR: a metabolic regulator and cell protector

(2008) Yan-Dong Wang et al.   CELL RESEARCH