Increased expression of complement components in tuberous sclerosis complex and focal cortical dysplasia type 2B brain lesions

Myelin Pathology Beyond White Matter in Tuberous Sclerosis Complex (TSC) Cortical Tubers

(2020) Angelika Mühlebner et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning

(2019) Carl M. Sellgren et al.   NATURE NEUROSCIENCE

Pathophysiology of neurodevelopmental mTOR pathway-associated epileptic conditions: Current status of biomedical research

(2019) Victoria Gruber et al.   CLINICAL NEUROPATHOLOGY

Identifying the role of complement in triggering neuroinflammation after traumatic brain injury

(2018) Ali Alawieh et al.   JOURNAL OF NEUROSCIENCE

Status epilepticus triggers long-lasting activation of complement C1q-C3 signaling in the hippocampus that correlates with seizure frequency in experimental epilepsy

(2018) Nicole D. Schartz et al.   NEUROBIOLOGY OF DISEASE

Local apoptotic-like mechanisms underlie complement-mediated synaptic pruning

(2018) Balázs A. Györffy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noninflammatory Changes of Microglia Are Sufficient to Cause Epilepsy

(2018) Xiaofeng Zhao et al.   Cell Reports

Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence

(2018) Andrea Arena et al.   BRAIN PATHOLOGY

Enhanced classical complement pathway activation and altered phagocytosis signaling molecules in human epilepsy

(2017) Season K. Wyatt et al.   EXPERIMENTAL NEUROLOGY

Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain

(2017) Maria I. Fonseca et al.   Journal of Neuroinflammation

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment

(2017) James D. Mills et al.   Scientific Reports

Complement activation at the motor end-plates in amyotrophic lateral sclerosis

(2016) Nawal Bahia El Idrissi et al.   Journal of Neuroinflammation

Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma

(2016) Pete A. Williams et al.   Molecular Neurodegeneration

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Novel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex

(2016) Angelika Mühlebner et al.   PLoS One

Complement C1q-C3-associated synaptic changes in multiple sclerosis hippocampus

(2015) Iliana Michailidou et al.   ANNALS OF NEUROLOGY

Complement emerges as a masterful regulator of CNS homeostasis, neural synaptic plasticity and cognitive function

(2014) Dimitrios C. Mastellos   EXPERIMENTAL NEUROLOGY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Epilepsy Related to Developmental Tumors and Malformations of Cortical Development

(2014) Eleonora Aronica et al.   Neurotherapeutics

TSC1 controls macrophage polarization to prevent inflammatory disease

(2014) Linnan Zhu et al.   Nature Communications

Evidence of Inflammatory System Involvement in Parkinson’s Disease

(2014) Yinxia Chao et al.   Biomed Research International

Evolving neurobiology of tuberous sclerosis complex

(2013) Peter B. Crino   ACTA NEUROPATHOLOGICA

TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement

(2013) Allison R Bialas et al.   NATURE NEUROSCIENCE

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Dendritic spine pathology in epilepsy: Cause or consequence?

(2012) M. Wong et al.   NEUROSCIENCE

Evaluation of the innate and adaptive immunity in type I and type II focal cortical dysplasias

(2010) Anand Iyer et al.   EPILEPSIA

Gene Expression Analysis of Tuberous Sclerosis Complex Cortical Tubers Reveals Increased Expression of Adhesion and Inflammatory Factors

(2009) Karin Boer et al.   BRAIN PATHOLOGY

The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response

(2008) Thomas Weichhart et al.   IMMUNITY

Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

(2007) K. Boer et al.   EPILEPSY RESEARCH