Amyloid-β induced membrane damage instigates tunneling nanotube-like conduits by p21-activated kinase dependent actin remodulation

Misfolded amyloid-β-42 impairs the endosomal–lysosomal pathway

(2020) Karen E. Marshall et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Bridging the gap: virus long distance spread via tunneling nanotubes

(2020) Robert J.J. Jansens et al.   JOURNAL OF VIROLOGY

Role of Membrane Tension Sensitive Endocytosis and Rho GTPases in the Uptake of the Alzheimer’s Disease Peptide Aβ(1-42)

(2020) Emelie Wesén et al.   ACS Chemical Neuroscience

Nucleolin regulates 14‐3‐3ζ mRNA and promotes cofilin phosphorylation to induce tunneling nanotube formation

(2020) Sunayana Dagar et al.   FASEB JOURNAL

Correlative cryo-electron microscopy reveals the structure of TNTs in neuronal cells

(2019) Anna Sartori-Rupp et al.   Nature Communications

Cofilin, a Master Node Regulating Cytoskeletal Pathogenesis in Alzheimer’s Disease

(2019) David E. Kang et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

(2018) Maitrayee Sardar Sinha et al.   ACTA NEUROPATHOLOGICA

Plasma membrane repair

(2018) Norma W. Andrews et al.   CURRENT BIOLOGY

Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cells

(2018) Joseph Jose Thottacherry et al.   Nature Communications

In vivo induction of membrane damage by β-amyloid peptide oligomers

(2018) Carl Julien et al.   Acta Neuropathologica Communications

Impact of high cholesterol in a Parkinson’s disease model: Prevention of lysosomal leakage versus stimulation of α-synuclein aggregation

(2017) Ida Eriksson et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The spread of prion-like proteins by lysosomes and tunneling nanotubes: Implications for neurodegenerative diseases

(2017) Guiliana Soraya Victoria et al.   JOURNAL OF CELL BIOLOGY

An In Vitro Model for Neuroscience: Differentiation of SH-SY5Y Cells into Cells with Morphological and Biochemical Characteristics of Mature Neurons

(2017) Lotta Agholme et al.   JOURNAL OF ALZHEIMERS DISEASE

α-synuclein transfer through tunneling nanotubes occurs in SH-SY5Y cells and primary brain pericytes from Parkinson’s disease patients

(2017) Birger Victor Dieriks et al.   Scientific Reports

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

(2016) Meryem Tardivel et al.   Acta Neuropathologica Communications

Extracellular vesicles are transferred from melanocytes to keratinocytes after UVA irradiation

(2016) Petra Wäster et al.   Scientific Reports

Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes

(2016) Elise Delage et al.   Scientific Reports

Selectivity of commonly used inhibitors of clathrin-mediated and caveolae-dependent endocytosis of G protein–coupled receptors

(2015) Shuohan Guo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Pseudorabies virus US3 triggers RhoA phosphorylation to reorganize the actin cytoskeleton

(2015) Thary Jacob et al.   JOURNAL OF GENERAL VIROLOGY

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques

(2015) Swetha Gowrishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance

(2014) Jakob Domert et al.   NEUROBIOLOGY OF DISEASE

Mitogen-activated protein kinase signaling pathways are involved in regulating α7 nicotinic acetylcholine receptor-mediated amyloid-β uptake in SH-SY5Y cells

(2014) W.N. Yang et al.   NEUROSCIENCE

The V-ATPase membrane domain is a sensor of granular pH that controls the exocytotic machinery

(2013) Sandrine Poëa-Guyon et al.   JOURNAL OF CELL BIOLOGY

Neuron-to-Neuron Transmission of Neurodegenerative Pathology

(2013) Martin Hallbeck et al.   NEUROSCIENTIST

Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis

(2013) David Freeman et al.   PLoS One

Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis

(2013) Ida Annunziata et al.   Nature Communications

Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of  -Amyloid

(2012) S. Nath et al.   JOURNAL OF NEUROSCIENCE

Identification of Novel Functional Inhibitors of Acid Sphingomyelinase

(2011) Johannes Kornhuber et al.   PLoS One

Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

(2010) Gunnar K. Gouras et al.   ACTA NEUROPATHOLOGICA

Tunneling-nanotube development in astrocytes depends on p53 activation

(2010) Y Wang et al.   CELL DEATH AND DIFFERENTIATION

Prion-like transmission of protein aggregates in neurodegenerative diseases

(2010) Patrik Brundin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

Microglia Mediate the Clearance of Soluble A  through Fluid Phase Macropinocytosis

(2009) S. Mandrekar et al.   JOURNAL OF NEUROSCIENCE

Virus entry by macropinocytosis

(2009) Jason Mercer et al.   NATURE CELL BIOLOGY

Prions hijack tunnelling nanotubes for intercellular spread

(2009) Karine Gousset et al.   NATURE CELL BIOLOGY

M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex

(2009) Koji Hase et al.   NATURE CELL BIOLOGY

An Isoform-Selective, Small-Molecule Inhibitor Targets the Autoregulatory Mechanism of p21-Activated Kinase

(2008) Sean W. Deacon et al.   CHEMISTRY & BIOLOGY

p21-activated Kinase-aberrant Activation and Translocation in Alzheimer Disease Pathogenesis

(2008) Qiu-Lan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis

(2008) Vincent Idone et al.   JOURNAL OF CELL BIOLOGY

Membrane nanotubes: dynamic long-distance connections between animal cells

(2008) Daniel M. Davis et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY