Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes

Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes

(2016) Saïda Abounit et al.   EMBO JOURNAL

Potential Role of the Formation of Tunneling Nanotubes in HIV-1 Spread in Macrophages

(2016) Michihiro Hashimoto et al.   JOURNAL OF IMMUNOLOGY

Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases

(2016) Saida Abounit et al.   Prion

Astrocyte-to-neuron intercellular prion transfer is mediated by cell-cell contact

(2016) Guiliana Soraya Victoria et al.   Scientific Reports

Senescent cells communicate via intercellular protein transfer

(2015) Anat Biran et al.   GENES & DEVELOPMENT

Prion aggregates transfer through tunneling nanotubes in endocytic vesicles

(2015) Seng Zhu et al.   Prion

Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer

(2015) Dominik Michael Frei et al.   Scientific Reports

Radiofrequency treatment alters cancer cell phenotype

(2015) Matthew J. Ware et al.   Scientific Reports

Erk regulation of actin capping and bundling by Eps8 promotes cortex tension and leader bleb-based migration

(2015) Jeremy S Logue et al.   eLife

The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration

(2015) Maddalena Costanzo et al.   BIOCHEMICAL JOURNAL

Dynamin1 Is a Novel Target for IRSp53 Protein and Works with Mammalian Enabled (Mena) Protein and Eps8 to Regulate Filopodial Dynamics

(2014) Ai Mei Chou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Membrane Nanotubes In Vivo: A Feature of MHC Class II + Cells in the Mouse Cornea

(2014) Holly R. Chinnery et al.   JOURNAL OF IMMUNOLOGY

Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function

(2014) Melanie Barzik et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors

(2014) David J Kast et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tunneling nanotube (TNT) formation is independent of p53 expression

(2013) V Andresen et al.   CELL DEATH AND DIFFERENTIATION

CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP

(2013) Andrea Disanza et al.   EMBO JOURNAL

Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes

(2013) M. Costanzo et al.   JOURNAL OF CELL SCIENCE

Myo10 is a key regulator of TNT formation in neuronal cells

(2013) K. Gousset et al.   JOURNAL OF CELL SCIENCE

Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance

(2013) Jennifer Pasquier et al.   Journal of Translational Medicine

Novel Binding Partners and Differentially Regulated Phosphorylation Sites Clarify Eps8 as a Multi-Functional Adaptor

(2013) Debbie L. Cunningham et al.   PLoS One

Membrane nanotubes in myeloid cells in the adult mouse cornea represent a novel mode of immune cell interaction

(2012) Yashar Seyed-Razavi et al.   IMMUNOLOGY AND CELL BIOLOGY

LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation

(2012) C. Schiller et al.   JOURNAL OF CELL SCIENCE

Wiring through tunneling nanotubes - from electrical signals to organelle transfer

(2012) S. Abounit et al.   JOURNAL OF CELL SCIENCE

Tunneling nanotube formation is essential for the regulation of osteoclastogenesis

(2012) Akira Takahashi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Tunneling nanotubes, an emerging intercellular communication route in development

(2012) Hans-Hermann Gerdes et al.   MECHANISMS OF DEVELOPMENT

Tunneling Nanotubes Provide a Unique Conduit for Intercellular Transfer of Cellular Contents in Human Malignant Pleural Mesothelioma

(2012) Emil Lou et al.   PLoS One

Multifaceted Roles of Tunneling Nanotubes in Intercellular Communication

(2012) Ludovica Marzo et al.   Frontiers in Physiology

Filopodia and adhesion in cancer cell motility

(2011) Antti Arjonen et al.   Cell Adhesion & Migration

The Eps8/IRSp53/VASP Network Differentially Controls Actin Capping and Bundling in Filopodia Formation

(2011) Federico Vaggi et al.   PLoS Computational Biology

Characterization of the role of dendritic cells in prion transfer to primary neurons

(2010) Christelle Langevin et al.   BIOCHEMICAL JOURNAL

Tunneling-nanotube development in astrocytes depends on p53 activation

(2010) Y Wang et al.   CELL DEATH AND DIFFERENTIATION

Myosin-X Induces Filopodia by Multiple Elongation Mechanism

(2010) Tomonobu M. Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tunnelling nanotubes

(2010) Karine Gousset et al.   Prion

Protruding membrane nanotubes: attachment of tubular protrusions to adjacent cells by several anchoring junctions

(2010) Maruša Lokar et al.   PROTOPLASMA

The key feature for early migratory processes

(2010) Claudia Schäfer et al.   Cell Adhesion & Migration

Molecular Basis for the Dual Function of Eps8 on Actin Dynamics: Bundling and Capping

(2010) Maud Hertzog et al.   PLOS BIOLOGY

Fas stimulation of T lymphocytes promotes rapid intercellular exchange of death signals via membrane nanotubes

(2009) Peter D Arkwright et al.   CELL RESEARCH

High Levels of Id1 Expression Define B1 Type Adult Neural Stem Cells

(2009) Hyung-song Nam et al.   Cell Stem Cell

Selective block of tunneling nanotube (TNT) formation inhibits intercellular organelle transfer between PC12 cells

(2009) Nickolay V. Bukoreshtliev et al.   FEBS LETTERS

Prions hijack tunnelling nanotubes for intercellular spread

(2009) Karine Gousset et al.   NATURE CELL BIOLOGY

M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex

(2009) Koji Hase et al.   NATURE CELL BIOLOGY

Eps8 Regulates Axonal Filopodia in Hippocampal Neurons in Response to Brain-Derived Neurotrophic Factor (BDNF)

(2009) Elisabetta Menna et al.   PLOS BIOLOGY

Tunneling nanotube (TNT)-like structures facilitate a constitutive, actomyosin-dependent exchange of endocytic organelles between normal rat kidney cells☆

(2008) Steffen Gurke et al.   EXPERIMENTAL CELL RESEARCH

The Cdc42 Effector IRSp53 Generates Filopodia by Coupling Membrane Protrusion with Actin Dynamics

(2008) Kim Buay Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

(2008) Stefanie Sowinski et al.   NATURE CELL BIOLOGY