Overexpression of miR-132-3p contributes to neuronal protection in in vitro and in vivo models of Alzheimer’s disease

MicroRNA miR-212 regulates PDCD4 to attenuate Aβ25–35-induced neurotoxicity via PI3K/AKT signaling pathway in Alzheimer’s disease

(2020) Yanjun Wang et al.   BIOTECHNOLOGY LETTERS

Developmental neurotoxicity in the context of multiple sevoflurane exposures: Potential role of histone deacetylase 6

(2019) Guohui Li et al.   NEUROTOXICOLOGY AND TERATOLOGY

miR-212-5p attenuates ferroptotic neuronal death after traumatic brain injury by targeting Ptgs2

(2019) Xiao Xiao et al.   Molecular Brain

miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients

(2019) Diana J. Cha et al.   Frontiers in Neuroscience

Environmental enrichment prevents Aβ oligomer-induced synaptic dysfunction through mirna-132 and hdac3 signaling pathways

(2019) Zhiyun Wei et al.   NEUROBIOLOGY OF DISEASE

MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways

(2018) Rachid El Fatimy et al.   ACTA NEUROPATHOLOGICA

Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons

(2018) Shan Huang et al.   FASEB JOURNAL

MiR-212 Attenuates MPP+-Induced Neuronal Damage by Targeting KLF4 in SH-SY5Y Cells

(2018) Yanfeng Song et al.   YONSEI MEDICAL JOURNAL

SIRT1, miR-132 and miR-212 link human longevity to Alzheimer’s Disease

(2018) A. Hadar et al.   Scientific Reports

Alzheimer’s disease

(2018) Richard Hodson   NATURE

miR-132/212 is induced by stress and its dysregulation triggers anxiety-related behavior

(2018) Sydney Aten et al.   NEUROPHARMACOLOGY

Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model

(2018) Karolina J. Janczura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA-132: a key noncoding RNA operating in the cellular phase of Alzheimer’s disease

(2017) Evgenia Salta et al.   FASEB JOURNAL

Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory

(2017) Philipp Mews et al.   NATURE

Downregulation of miR-132/212 impairs S-nitrosylation balance and induces tau phosphorylation in Alzheimer's disease

(2017) Yang Wang et al.   NEUROBIOLOGY OF AGING

Rapamycin upregulates glutamate transporter and IL-6 expression in astrocytes in a mouse model of Parkinson’s disease

(2017) Yunlong Zhang et al.   Cell Death & Disease

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Therapeutic effects of histone deacetylase inhibitors in a murine asthma model

(2016) Yuan Ren et al.   INFLAMMATION RESEARCH

miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregationin vivo

(2015) Pascal Y. Smith et al.   HUMAN MOLECULAR GENETICS

HDAC inhibitor–dependent transcriptome and memory reinstatement in cognitive decline models

(2015) Eva Benito et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease

(2014) J. Banzhaf-Strathmann et al.   EMBO JOURNAL

Histone Decacetylase Inhibitors Prevent Mitochondrial Fragmentation and Elicit Early Neuroprotection against MPP+

(2013) Min Zhu et al.   CNS Neuroscience & Therapeutics

Alteration of the microRNA network during the progression of Alzheimer's disease

(2013) Pierre Lau et al.   EMBO Molecular Medicine

De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease

(2013) Hon-Kit Andus Wong et al.   HUMAN MOLECULAR GENETICS

HDAC Inhibition Facilitates the Switch between Memory Systems in Young But Not Aged Mice

(2013) M. Dagnas et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-195 Protects Against Dementia Induced by Chronic Brain Hypoperfusion via Its Anti-Amyloidogenic Effect in Rats

(2013) J. Ai et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-98 induces an Alzheimer’s disease-like disturbance by targeting insulin-like growth factor 1

(2013) Yi-Kui Hu et al.   Neuroscience Bulletin

1–42 β-Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death

(2013) L Manterola et al.   Translational Psychiatry

Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target

(2012) G. Shaltiel et al.   Brain Structure & Function

Genes Are Often Sheltered from the Global Histone Hyperacetylation Induced by HDAC Inhibitors

(2012) John Halsall et al.   PLoS One

MicroRNA networks direct neuronal development and plasticity

(2011) N. F. M. Olde Loohuis et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

(2011) Maria Manczak et al.   HUMAN MOLECULAR GENETICS

Target Gene Repression Mediated by miRNAs miR-181c and miR-9 Both of Which Are Down-regulated by Amyloid-β

(2011) Nicole Schonrock et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

MicroRNA-137/181c Regulates Serine Palmitoyltransferase and In Turn Amyloid  , Novel Targets in Sporadic Alzheimer's Disease

(2011) H. Geekiyanage et al.   JOURNAL OF NEUROSCIENCE

Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance

(2010) Alessia Peserico et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Transgenic miR132 Alters Neuronal Spine Density and Impairs Novel Object Recognition Memory

(2010) Katelin F. Hansen et al.   PLoS One

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY