1–42 β-Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death

Rac1 Protein Regulates Glycogen Phosphorylase Activation and Controls Interleukin (IL)-2-dependent T Cell Proliferation

(2012) Onetsine Arrizabalaga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: Implications for early intervention and therapeutics

(2011) Peizhong Mao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits

(2011) Ger J.A. Ramakers et al.   HUMAN MOLECULAR GENETICS

Age-dependent Accumulation of Soluble Amyloid β (Aβ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein-α (sAPPα) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3β Pathway in Alzheimer Mouse Model

(2011) Sebastian Jimenez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP–treated PC12D cells

(2011) Akihiro Goto et al.   MOLECULAR BIOLOGY OF THE CELL

Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors

(2010) Elena Alberdi et al.   CELL CALCIUM

Rac and Rho GTPases in cancer cell motility control

(2010) Matteo Parri et al.   Cell Communication and Signaling

The Insulin/Akt Signaling Pathway Is Targeted by Intracellular β-Amyloid

(2009) Han-Kyu Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

(2009) Fernanda G. De Felice et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Onset Familial Alzheimer Disease With Spastic Paraparesis, Dysarthria, and Seizures and N135S Mutation in PSEN1

(2008) Leslie A. Rudzinski et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Protein Kinase C-  Mediates Neuronal Apoptosis in the Retinas of Diabetic Rats via the Akt Signaling Pathway

(2008) Y.-H. Kim et al.   DIABETES

Rho GTPases in cancer cell biology

(2008) Francisco M. Vega et al.   FEBS LETTERS

p21-activated Kinase-aberrant Activation and Translocation in Alzheimer Disease Pathogenesis

(2008) Qiu-Lan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dendritic Spine Loss and Synaptic Alterations in Alzheimer’s Disease

(2008) Marlen Knobloch et al.   MOLECULAR NEUROBIOLOGY

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

(2007) Fernanda G. De Felice et al.   NEUROBIOLOGY OF AGING